R&D; Systems Antibody Types
Polyclonal antibodies offer multiple epitope recognition. Anti-sera and whole immunoglobulin (Ig) preparations contain a large amount of non-specific Ig, which could lead to non-specific antibody binding. Antigen column affinity chromatography eliminates non-specific IgG making these specific IgG preparations, in general, 10-fold more potent.
MonoclonalMonoclonal antibodies offer monospecificity, recognizing a single epitope. All new R&D; Systems' monoclonal antibodies are derived from hybridoma culture supernatants rather than ascites fluid and are purified using either protein A or protein G columns.