The Overarching Role of Growth Hormone in Aging
A decline in the secretion of the growth hormone has been recorded with aging in the human body. This downward trajectory is primarily associated with physiological changes, which are available with young adult patients struggling with growth hormone deficiency. The typically recorded changes include a decline in lean body mass and improvement in muscle strength and body fat, especially in the visceral compartment. It’s essential to mention that both memory and cognitive function deteriorate slowly with age. Furthermore, deep sleep can shorten the period, along with a reduction in nighttime GH secretion. This effectively contributes to sleep disorders, becoming a noticeable clinical problem in old age.
Age-Related Changes in Growth Hormone Secretion
It’s essential to mention that the like of trophic hormones that emerge into the physiological scene at puberty, including sex steroids and HGH levels, dramatically impact the body’s composition and strength. The HGH levels gain a stable progression during young adult life, only then to take a downward curve, accompanied by loss of muscle mass and aerobic capacity, albeit with increased abdominal fat.
As mentioned already, the body experiences a progressive dip of about 15% per decade in growth hormone secretion upon reaching the third decade of life. Any GH secretion, irrespective of the body age, is typically characterized by lack of day-night GH rhythm, only due to loss of nocturnal sleep-related GH pulses. It’s essential to mention that Growth Hormone Binding Protein starts decreasing post the age of sixty years, at this moment improving bioavailable growth hormone. Medical professionals and researchers expect this decrease to parallel growth hormone receptors with age.
Decrease In HGH In Normal Aging: Similarities And Differences Between Adult Growth Hormone Deficiency
Despite not being a mirror reflection of aging, the Adult Growth Hormone Deficiency (AGHD) is generally considered as the top grade reference point for data on various symptoms of reduced Growth Hormone secretion, side effects of GH replacement post-treatment effects and appropriate dosing strategies for adults. There’s no denying that multiple aspects of ordinary aging mirror the AGHD syndrome features – even the loss of muscle and bone mass, increased visceral fat and cardiac capacity, diminishing exercise, thinning of the skin, and many psychological, cognitive problems and atherogenic alterations in lipid profile.
Here’s a further breakdown of the distinctive pointers of an average decrease in Growth Hormone secretion related to aging from true AGHD. It’s essential to mention that aging can be defined as a relative physiologic Growth Hormone deficiency- aging is by no means a disease in itself and drastically different from AGHD. The higher Growth Hormone secretion and physiological responses recorded in older adults compared to AGHD patients of similar age further prove the claim. If you have been tested for hormones and you have a deficiency in HGH, we recommend HGH for sale.
It’s only necessary to mention that biochemical tests for AGHD diagnosis are not genuine, as their accuracy is impacted by the pre-test probability of AGHD. Hence the medical practitioners and doctors must consider the clinical context to identify the likelihood of growth hormone deficiency.