In Poland, twenty-five cases of diphtheria, mostly among adults (including five foreigners) in the region adjacent to the eastern border were registered in the years 1992-1996.
In 1993-1994, because of the threat of diphtheria infection, 41 healthy members of the medical staff of the University Hospital of Infectious Diseases in Krak6w, mainly women aged 25-57 years were immunized with Td and d vaccines with a 6-month interval between courses.
Prior to vaccination, 17 (41%) individuals showed a lack of diphtheria antibodies as determined with a passive haemagglutination test. 14 of them were aged 30-49 years.
Six months after the 2nd dose of vaccine, all seronegative persons had developed a protective level of antibodies.
Moreover, all vaccinated subjects showed a statistically significant increase of the antibody titre between the first and last serological examinations.
Mots-clés Pascal : Corynebacterium diphtheriae, Corynebacteriaceae, Actinomycetes, Bactérie, Homme, Diphtérie, Bactériose, Infection, Vaccination, Personnel sanitaire, Milieu hospitalier, Prévention, Immunoprotection, Epidémiologie, Prévalence, Pologne, Europe
Mots-clés Pascal anglais : Corynebacterium diphtheriae, Corynebacteriaceae, Actinomycetes, Bacteria, Human, Diphtheria, Bacteriosis, Infection, Vaccination, Health staff, Hospital environment, Prevention, Immunoprotection, Epidemiology, Prevalence, Poland, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0351200
Code Inist : 002B05B02A. Création : 14/12/1999.