Guillain-Barre syndrome is an exotic disorder faced by the minority. It happens when the immune system gets confused enough to affect body’s nerves. When the limbs become extremely weak and sensitive, it may be the first symptom. The pain and uncomfortable feeling spread to other parts of the body very soon. The worst outcome is the complete body paralysis. Many people die of shock; others just can’t stand the sharp pain. A medical emergency is the result of the most serious case, so you should be ready to call emergency. Immediate hospitalization is needed.