The total oral dose of alendronate was calculated by multiplying the daily dose by the amount of days it was taken. Comparisons of interest had been specified a priori. Consequently, when you compare groups with respect to the quantity of normal-appearing osteoclasts, we tested only the hypothesis that the number of such osteoclasts was higher in the group getting 10 mg of alendronate per day than in the placebo group. Pearson correlation coefficients were used to test for an association between your number of osteoclasts and the quantity of alendronate administered. Patients for whom treatment with alendronate was halted after 2 years were excluded, although very similar results were attained when all patients were included. All cell counts, including zeroes, were included in the analyses.‘Our findings imply the better your asthma is normally controlled, the much more likely you are with an appropriate response to a virus,’ said Dr. Michelle Gill, assistant professor of pediatrics and inner medicine at UT Southwestern and lead author of the study appearing on the web and in the June edition of The Journal of Immunology. ‘When people with asthma come in contact with an allergic result in and a respiratory virus, the allergen may actually hinder the immune response to the virus. This interruption in the antiviral response may donate to exacerbations of asthma that are generally connected with respiratory viral infections.’ More than half of the 20 million people diagnosed with asthma in the U.S., including 2.5 million children, have been identified as having allergic asthma.