May 20, 2013
Bone Marrow Culture
Bone marrow culture is an examination of the soft, fatty tissue found inside certain bones. This tissue, called bone marrow, produces blood cells. This test is done to find out if there is an infection inside the bone marrow.
Back to TopAlternative Names
Culture - bone marrow
Back to TopHow the Test Is Performed
The doctor removes a sample of your bone marrow from the back of your pelvic bone or breast bone. This is usually done with a small needle inserted into your bone, which is called a bone marrow aspiration or a biopsy.
The removed tissue is sent to a lab. It is placed into a special container called a culture dish. Every day, the laboratory specialist will look at the tissue under a microscope to see if any bacteria, fungi, or viruses have grown.
If any bacteria, fungi, or viruses are found, other tests may be done to learn which drugs will kill the organisms. Treatment can then be started based on these results.
Back to TopHow the Test Will Feel
You may feel pressure and pain as the marrow is being removed. (You may be given some numbing medicine, called anesthesia, before the procedure.)
Soreness at the site usually lasts from a few hours to 1-2 days.
Back to TopWhy the Test Is Performed
You may have this test if you have an unexplained fever or if your health care provider thinks you have an infection of the bone marrow.
Back to TopNormal Results
No growth of bacteria, viruses, or fungi in the culture is normal.
Back to TopWhat Abnormal Results Mean
Abnormal results suggest that you have an infection of the bone marrow. The infection may be from bacteria, viruses, or fungi.
Back to TopRisks
Back to TopConsiderations
Fluid (aspirate) or a piece of tissue (biopsy specimen) from the bone marrow may be sent to the laboratory for many different types of tests. These tests study how immature blood cells look, and how they are developing.
Back to TopReferences
Castro-Malaspina H, O'Reilly R. Aplastic anemia and related disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine . 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 171.
Murray PR, Witebsky FG. The clinician and the microbiology laboratory. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Disease . 7th ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 227.
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