Korean artist Kang Duck-Bong makes PVC pipe sculptures that look like they’re moving.
(via colossal)Tags: art Kang Duck-Bong
In this transcript of a talk given to the attendees of the Joint Summits on Translational Science, Carl Zimmer highlights an important aspect of understanding the human body and how to treat its many maladies: the ecosystem of microbes.
Tags: biology Carl Zimmer science
The microbes in your body at this moment outnumber your cells by ten to one. And they come in a huge diversity of species — somewhere in the thousands, although no one has a precise count yet. By some estimates there are twenty million microbial genes in your body: about a thousand times more than the 20,000 protein-coding genes in the human genome. So the Human Genome Project was, at best, a nice start. If we really want to understand all the genes in the human body, we have a long way to go.
Now you could say “Who cares? They’re just wee animalcules.” Those wee animacules are worth caring about for many reasons. One of the most practical of those reasons is that they have a huge impact on our “own” health. Our collection of microbes-the microbiome-is like an extra organ of the human body. And while an organ like the heart has only one function, the microbiome has many.
When food comes into the gut, for example, microbes break some of them down using enzymes we lack. Sometimes the microbes and our own cells have an intimate volley, in which bacteria break down a molecule part way, our cells break it down some more, the bacteria break it down even more, and then finally we get something to eat.
Another thing that the microbiome does is manage the immune system. Certain species of resident bacteria, like Bacteroides fragilis, produce proteins that tamp down inflammation. When scientists rear mice that don’t have any germs at all, they have a very difficult time developing a normal immune system. The microbiome has to tutor the immune system in how to do its job properly. It also acts like an immune system of its own, fighting off invading microbes, and helping to heal wounds.
While the microbiome may be an important organ, it’s a peculiar one. It’s not one solid hunk of flesh. It’s an ecosystem, made up of thousands of interacting species.
Monty Python member Terry Jones is set to direct a sci-fi comedy that will feature other Python members “voicing key roles”. Gilliam, Cleese, and Palin have all signed on and they’re working on getting Eric Idle.
Members of Monty Python’s Flying Circus are reteaming for “Absolutely Anything,” a sci-fi farce combining CGI and live action, with Terry Jones to direct and Mike Medavoy to produce.
Plans are for filming to begin in the U.K. this spring, with the Pythons voicing key roles as a a group of aliens who endow an earthling with the power to do “absolutely anything” to see what a mess he’ll make of things — which is precisely what happens. There’s also a talking dog named Dennis who seems to understand more about the mayhem that ensues than anyone else does. Robin Williams will voice the character.
“It’s not a Monty Python picture, but it certainly has that sensibility,” Jones told Variety.
(via ★vuokko)Tags: Absolutely Anything Monty Python movies
Typographica shares their favorite typefaces of 2011.
(via ★essl) Tags: best of best of 2011 lists typography
The idea is simple: I invite a group of writers, educators, type makers and type users to look back at 2011 and pick the release that excited them most.
Maybe I’m just way over-cautious but this guy does almost kill himself while bungee jumping off a bridge using a jury-rigged climbing rope and harness, right? This is just totally batshit crazy:
Skip ahead to about 1:30…everything before that is just filler. (via ★bryce)Tags: video
Aaron Cohen calls this “the best story you’ll read about a burglary you’ll read this week” and I think he’s right.
Tags: crime John Davidson
When John Davidson’s apartment gets robbed, he learns that the easiest way to get his stuff back is to have one drug dealer lie to another drug dealer while he lies to the police.
Posters for Oscar nominated movies that maybe tell the truth of each movie a bit more than the conventional posters. For instance, Iron Lady becomes Total Bitch, Tree of Life becomes Wuh?, and The Girl with the Dragon Tattoo becomes All the Rape, No Subtitles.
(via ★vuokko)Tags: design movies remix
That’s right, two exclamation points because this blows my mind. John Tyler was the 10th President of the United States. He was born in 1790 and took office in 1841. His son, Lyon Gardiner Tyler, was born in 1853, when Tyler was 63 years old1. Lyon had six children with two different wives2, two of whom were Lyon Gardiner Tyler, Jr. (born 1924 when Lyon Sr. was 71) and Harrison Ruffin Tyler (born 1928 when Lyon Sr. was 75). They are reportedly both still living in their 80s.
Someone needs to come up with a term for this sort of thing (history bridges? no.). There’s also this 1956 game show appearance of a Lincoln assassination eyewitness and Supreme Court Justice Oliver Wendell Holmes (1841-1935) shaking hands during his lifetime with both John Quincy Adams (b 1767) and John F Kennedy (d 1963), one man spanning 200 years of American history. (via ★mattbucher)
 Tyler actually had two children after Lyon…Robert was born when he was 65 and Pearl followed at 70. ↩
 Lyon’s second wife was 36 years his junior and actually younger than each of his three previous children. ↩Tags: history John Tyler
Adrian Chen has an interview with a renegade IT guy named Martin who does social media, hacking, and other tech stuff for “High Net-worth Individuals” and criminals. One of things he does is set up drug rings with prepaid cell phones and a rotating collection of SIM cards a la the Barksdale/Bell drug crew in The Wire.
With Martin’s system, each crewmember gets a cell phone that operates using a prepaid SIM card; they also get a two-week plastic pill organizer filled with 14 SIM cards where the pills should be. Each SIM card, loaded with $50 worth of airtime, is attached to a different phone number and stores all contacts, text messages and call histories associated with that number, like a removable hard drive. This makes a new SIM card effectively a new phone. Every morning, each crewmember swaps out his phone’s card for the card in next day’s compartment in the pill organizers. After all 14 cards are used, they start over at the first one.
Of course, it would be hugely annoying for a crewmember to have to remember the others’ constantly changing numbers. But he doesn’t have to, thanks to the pill organizers. Martin preprograms each day’s SIM card with the phone numbers the other members have that day. As long they all swap out their cards every day, the contacts in the phones stay in sync. (They never call anyone but each other on the phones.) Crewmembers will remind each other to “take their medicine,” Martin said.
That’s clever. The “take their medicine” detail reads like it’s straight out of the movies.Tags: Adrian Chen crime The Wire
Economist Jason Barr and his colleagues measured the bedrock depth in Manhattan and correlated it with building height. In doing so, they busted the long-held belief that there were no skyscrapers between Midtown and the Financial District because of insufficient bedrock.
What the economists found was that some of the tallest buildings of their day were built around City Hall, where the bedrock reaches its deepest point in the city, about 45 meters down, between there and Canal Street, at which point the bedrock begins to rise again toward the middle of the island. Indeed, Joseph Pullitzer built his record-setting New York World Building, a 349-foot colossus, at 99 Park Row, near the nadir, as did Frank Woolworth a decade later.
(via @bobulate)Tags: architecture cities economics NYC
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