Mammalian cell death after exposure to radiation after a dose D of radiation often follows the linear-quadratic model.
Create an XY table. Enter radiation doses into X and number of dead cells into Y. After entering data, click Analyze, choose nonlinear regression, choose the panel of linear-quadratic equations, and choose Linear quadratic: Y is number of cells dead.
Consider constraining Y0, the number of cells alive when X=0, to a constant value.
X: Dose of radiation
Y: Number of cells surviving
A: Coefficient for linear killing
B: Coefficient for quadratic killing
Y0: Number of cells alive when X=0.