Sickle cell disease (SCD) is a common inherited blood disorder in the United States, affecting an estimated 70,000 to 100,000 Americans. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. The 6 Most Common Types of Anemia, Anemia is a condition in which the body lacks the amount of red blood cells to keep up with the body’s demand for oxygen. The most serious type is called sickle cell anaemia. 1 … The genes inherited from the parents determines the type of hemoglobin the person makes in red blood cells (RBC). The reason why sickle cell seem to be … 1 0. Source(s): biology. The main causes of anemia are bleeding, hemolysis (excessive destruction of… . CDC considers SCD a major public health concern and is committed to conducting surveillance, raising awareness, and promoting health education. Both males and females have an equal chance of getting sickle cell as it is not a sex-linked disease. Sickle cell disease is the name for a group of inherited health conditions that affect the red blood cells. Anemia can be temporary or long term, and it can range from mild to severe. This implies that an individual will exhibit this condition only if both the alleles (homozygous) of the HBB gene, possessed by him/her, are mutated. Bone and joint disorders are the most common cause of chronic pain in patients who have sickle cell disease. Angel . 1 decade ago. SCD can lead to lifelong disabilities and reduce average life expectancy. Males. In the United States, it’s estimated that sickle cell anemia affects 70,000–100,000 people, mainly African Americans. The most common type is known as sickle cell anaemia (SCA). PS- I'm no pro :-) 1 1. 1 0. beckbabe88. This leads to a rigid, sickle-like shape under certain circumstances. These individuals usually perish at an early age. Sickle cell anaemia is a genetic condition caused by an alteration in a single DNA base, it its clinical manifestations are influenced by other genes and behavioral and environmental factors (Piel, Stienberg, Rees, 2017). Sickle cell disease is particularly common in people with an African or Caribbean family background. The genes responsible for sickle cell disease are located on chromosome 11. Anonymous. Sickle cell anemia is most common in people whose families come from Africa, South or Central America (especially Panama), Caribbean islands, Mediterranean countries (such as Turkey, Greece, and Italy), India, and Saudi Arabia. However, this does not mean that people with only one mutated allele (heterozygote) are not affected at all. Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents. Sickle cell anemia is a disease caused by the genetic inheritance of mutated alleles responsible for the condition. Autosomal means that the gene is on one of the first 22 chromosomes that do not determine gender, so that males and females are equally affected by the disease. Sickle cell anemia (SCA) is an autosomal recessive disorder. One of the most common genetic disorders is sickle cell anaemia (Sinicki). 1 decade ago.