Although we understand stem cell’s role in the body, the subtleties of extracellular communication remain a difficult system to analyze. An international group of researchers has recently discovered an intricate cell-to-cell communications system used by stem cells. The findings will help scientists develop new stem cell-based treatment options for peripheral artery disease, a condition which affects about 12 million people in the United States alone.
Past research had been focused on developing different tissues from stem cells. Current research suggests a novel therapeutic use of stem cells that heal tissue by homing in on damaged tissues and encouraging more cells to help out in the revascularization process.
“We have provided the first comprehensive snapshot of the communication proteins’ stem cells and their exosomes use to talk to other cells,” said Johnathon Anderson, lead author of the study, “It has enabled us to fundamentally grasp how stem cells use this newly identified communication system to heal damaged tissues that have reduced or cut off blood flow in individuals suffering from peripheral arterial disease.”
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