Doctor insights on:
Autoimmune Bone Marrow Disease
The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
Bone marrow disease: The symptoms are related to the abnormality of the bone marrow function -i.e. Decrease production of the blood cell counts-or increase level of blood cells counts if something supresses bone marrow function-anemia, decrease WBC and platelet can happen. -symptoms will include fatigue, infection, fever, bleeding. If the cell count is too much-clots, fatigue, feeling sluggish can happen. ...Read more
It varies greatly: Bone marrow has lots of reserve, so it can be partly diseased, yet the body has no effect. But once the bone marrow is completely diseased or damaged, then the body will have all kinds of effects in the form of anemia (low hemoglobin), low WBC and low platelet counts and the complications of infections and bleeding as a result of low blood counts. ...Read more
No.: The very definition of a disease is that it is a condition which adversely affects health. So if you really have a disease in the marrow it's likely to make you feel sick sooner or later. ...Read more
Good question: Great question. Difficult to describe in 400 characters. Here is a great explanation: http://goo. Gl/rpdpp. ...Read more
What is the prognosis for someone whose cold agglutin disease is suspected to have been caused by a virus, with negative for lymphoma bone marrow test?
Prognosis good: Cold agglutinins often come and go with a mycoplasma like chest cold. I trust this is not actually a cryoglobulin. ...Read more
Many: The main lethal disease treated with stem cell transplants are hematologic malignancies such as leukemia, lymphoma and myeloma. Bone marrow failure (aplastic anemia) is also treated with stem cell transplants. Some life-threatening genetic disease can also be treated with a transplant. ...Read more
Is myelofibrosis a terminal disease? Does it just keep progressing until all bone marrow is replaced by scar tissue that can't produce blood?
Progressive: Yes, you described it well. New treatments are becoming available all the time, and they could extend your life! Get treated! ...Read more
No clear results.: There is not level 1 evidence to show bone marrow transplant increases survival in patients with sickle cell disease. Although there are several reports with success a systematic randomized trial remains to be done. Bone marrow transplant is a procedure with multiple complications. After the procedure the recipient has to take meds for life. Cost/effective therapy analyses are not present. ...Read more
What diseases cause bone marrow to produce the right cells but not fast enough in a 8 year old boy with low red/white cells, low platelets + neoutroph?
Viral: Viral diseases often. Blood disorders can cause the same in early stages. Some conditions are inherited. ...Read more
Will my bone marrow test show up for leukemia lupus etc, while I am on these IV treatments for my blood platelet disease?
Microscope: The cells from the marrow are analyzed under a microscope by a pathologist who can tell when the cells have abnormal growth and appearance. ...Read more
It is a mild form of leukemia and may not cause symptoms. Some patients do develop complications. There is no cure through conventional treatments. In some cases bone marrow transplant may be warranted and can cure the disease. See this site for more info.
http://www. Mayoclinic. Org/diseases-conditions/thrombocythemia/basics/definition/con-20034386 ...Read more
Blood related.: A bone marrow transplant gives someone a new immune system, and new cells from which to make red cells, white cells and platelets. Bmt can cure genetic hemoglobin disease like thalassemia major, where a person cannot make red cells. Bmt can cure congenital neutropenias (very low white cells). Immune system defects such as severe combined immune deficiency (scid) are candidates too. ...Read more
My mom in law bone marrow report says low grade unclassified b cell lymphoproliferative disorder what does it suggest is it something serious?
Is it safe to have cosmetic filler like botera if you have chronic myeloproliferative disorder. This is a bone marrow disorder?
Probably safe: Most dermal fillers are non allergenic and are inert. They should not react or have problems with medical issues. They are also inject superficially and not internally. ...Read more
A person has pnh, normocellular bone marrow, but has falling neutrophils and platelets. No mds or other clonal disorder. R/o what else?
My mom in law bone marrow report says low grade unclassified b cell lymphoproliferative disorder what does it suggest is it a blood cancer?
Yes, more w/u needed: Yes, low grade b cell lymphoproliferative disorder a.K.A lymphoma is a type of blood cancer. There are many types of b cell lymphoproliferative disorder from the low grade/less agressive to high grade/more agressive. Here, I think, more work up needs to be done- particularly to classify what type of lymphoproliferative disorder this is and also how much tumor burden and prognostication. D/w md. ...Read more
All childhood blood disorders that cause bone marrow to produce cells but slowly, low red cells white and platelets, B12 and iron are all in range?
Many conditions: Pancytopenia, or decrease in rbc, wbc, and platelets can be genetic, like Fanconi anemia or Dyskeratosis congenital, that include other abnormalities. Acquired pancytopenia, besides low B12 and Folate, (folic acid) can be caused by a toxin, drugs, radiation, a viral infection, malnutrition and myelodysplastic syndrome (MDS). If a cause is not found, it is said to be idiopathic. I hope it resolves. ...Read more
Register as a Donor: You can register in any blood bank by asking about the national marrow donor program (nmdp) also called: be the match registry. It is simple to register as a potential donor by giving a sample of body cells, usually taken from inside of your cheek. Once they find your body cells match someone in need they will call you to donate your blood stem cells or marrow stem cells. ...Read more
Bone marrow tests are performed for many reasons, but the commonest ones are:
detecting bone marrow involvement by a cancer - many cancers, notably lymphomas spread from their primary site to different organs of the body, including the bone marrow
detecting cancers of the blood leukemias
finding the cause of anemia.
Bone marrow infiltration by other diseases ...Read more
HLA type: Every cell in your body has human leukocyte antigens (hlas) on the surface that act like a cell i.D. These allow your immune cells to recognize your cells as part of you and not foreign cells that need to be attacked. The bone marrow donor's hlas should match the patient's hlas as closely as possible so the donor's immune system doesn't attack the patient! Hla is determined by a blood test. ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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