Forsyth scientists suggest linkages between obesity and oral bacterial infection
... study, the researchers demonstrated that the salivary
bacterial composition of overweight women differs ...
Summary of Study
In order to measure the salivary
bacterial populations of overweight women, ... seven of the 40 species studied occurred in the salivary
bacteria of subjects in the overweight group. In ...
Keeping chromosomes from cuddling up
... II affects chromosomes, the researchers used the salivary
glands from normal Drosophila melanogaster fruit flies. Fruit fly salivary
glands are unusual, because they have many copies ... positions.
The scientists then looked at the salivary
glands at the two temperatures to see what ...
Green tea may delay onset of type 1 diabetes
... EGCG reduced the severity and delayed onset of salivary
gland damage associated with Sjogren's syndrome, ... the abnormality at the molecular level in the salivary
gland. It also significantly lowered the serum ... so the immune cells attack the pancreas and salivary
glands until they are no longer functional."
Nitrates in vegetables protect against gastric ulcers
In the body the blood circulation transports nitrates to the salivary
glands, where they are concentrated. When we have eaten nitrate-rich food ... ulcers.
In the body the blood circulation transports nitrates to the salivary
glands, where they are concentrated. When we have eaten nitrate-rich food ...
Komodo even more deadly than thought: Research
... wrong," says research co-author, Dr Stephen Wroe from the University of New South Wales, Australia. "The dragon is truly poisonous. It has modified salivary
glands that deliver both hypertensive and anti-blood-clotting agents, which, in combination with lightweight but sophisticated cranial and dental ...
American Chemical Society Weekly PressPac -- April 1, 2009
... bite into the skin. Until now, however, nobody had identified the specific chemicals involved in this devious action.
The scientists collected salivary
glands from hundreds of adult female black flies and isolated the proteins using high-tech analytical gear. They identified 72 different proteins, ...
Taste, odor intervention improves cancer therapy, according to Virginia Tech, Wake Forest study
... and spices to enhance flavors in some cases, practice good oral hygiene, and use agents such as sugar free gums and sour tasting drops to stimulate salivary
Dietrich explained their study of the literature, and synopsis of it, is meant to increase the recognition by oncologists and ...
Tufts University professor receives IADR Pharmacology/Therapeutics/Toxicology Award
... clinical trials involving various aspects of dry mouth (xerostomia), including
drug therapy for patients with Sjgren's syndrome, devices to stimulate salivary
flow, and understanding why patients with dry
mouth are susceptible to tooth decay. She has spearheaded numerous other areas of therapeutic research ...
American Chemical Society's weekly PressPac -- Jan. 14, 2009
... tests for diabetes screening, detection, and monitoring, the researchers say. MTS
ARTICLE #2 FOR IMMEDIATE RELEASE
"Proteomic Identification of salivary
Biomarkers of Type-2 Diabetes"
DOWNLOAD FULL TEXT ARTICLE http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/pr8003776
American Chemical Society's Weekly PressPac -- Jan. 7, 2009
... development of central nervous system in early infancy that are involved in ASD. MTS
ARTICLE #3 FOR IMMEDIATE RELEASE
"Hypo-Phosphorylation of salivary
Peptidome as a Clue to the Molecular Pathogenesis of Autism Spectrum Disorders"
DOWNLOAD FULL TEXT ARTICLE ...
Saliva proteins could help detection of oral cancer
... the proteomic components of saliva in healthy subjects. This work, also supported by NIDCR, demonstrates the first translational utility of the salivary
proteome for oral cancer detection.
Researchers collected saliva samples from 64 patients with oral squamous cell carcinoma and 64 healthy ...
Athletes' 'sweat and tears' linked to asthma
... to methacholine compared with those who were responsive. Additionally, a significant correlation was found between sweat secretion and unstimulated salivary
gland flow rates and tear secretion.
"There were many Olympic hopefuls whose competitive chances were potentially limited by exercise-induced ...
CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients
... of chemoradiation-induced oral mucositis.
Oral Mucositis: A Common and Debilitating Condition
Oral complications including mucositis and salivary
gland dysfunction are common and often debilitating side effects of cancer therapy. OM is estimated to affect more than 400,000 cancer patients each ...
Cold Spring Harbor Protocols features classic approaches for analyzing chromosomes
... Polytene Chromosomes by Immunostaining" takes advantage of the formidable size and structure of the large polytene chromosomes found in Drosophila salivary
glands. These easily dissected chromosomes allow mapping of chromosomal protein distributions at very high resolution. The protocol, written by ...
Saliva can help diagnose heart attack, study shows
... thrombosis and acute coronary syndrome. They found these proteins were in higher concentrations in saliva of heart attack victims, and that specific salivary
proteins were as accurate in the diagnosis of heart attack as those found in blood serum using current testing methods.
These are truly exciting ...
Monkey malaria widespread in humans and potentially fatal
Malaria, which kills more than one million people each year, is caused when Plasmodium parasites are passed into the bloodstream from the salivary
glands of mosquitoes. Some types, such as P. falciparum, found most commonly in Africa, are more deadly than others. P. malariae, found in tropical ...
Research sheds light on the mechanics of gene transcription
... Webb that allows high-precision 3D imaging in living cells, the researchers observed polytene chromosomes -- giant, multistranded chromosomes in the salivary
gland tissue of fruit flies that have hundreds of sets of the genome instead of the usual two sets in conventional cells.
They activated heat shock ...
Tips from the Journals of the American Society for Microbiology
... by a high fever and rash. Studies indicate that by age 3 the majority of children have been infected by HHV-6, after which the virus persists in the salivary
glands into adulthood. The virus may remain dormant or reactivate in immunocompetent or immunocompromised individuals.
Over a span of four ...
Extra gene copies were enough to make early humans' mouths water
... That's one interpretation of a discovery, published online September 9 in Nature Genetics, which indicates that humans carry extra copies of the salivary
Humans have many more copies of this gene than any of their ape relatives, the study found, and they use the copies to flood their ...
Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring
... Device for Reducing Psychosocial Stress
Vivek Shetty, D.D.S., Dr. Med.Dent., University of California, Los Angeles
Biosensor of Psychosocial Stress
Improved Measures of Diet and Physical Activity
Tom Baranowski, Ph.D., Baylor College of ...
The insect vector always bites twice
... cases, the parasite moves back into the vector’s salivary
glands in order to be transmitted to the human ... or uninfected, exposed to bites. Comparison of salivary
protein immunogenic profiles obtained showed that ... of these species.
Starting from immunogenic salivary
proteins, simple and effective prevention tools ...
LIAI scientists make important finding on cytomegalovirus transmission
... have shown that cytomegalovirus (CMV) in the salivary
glands can be reduced ?and in some cases ... exploits IL-10-mediated immune regulation in the salivary
glands." LIAI scientists Ian Humphreys, Ph.D., ... chronic virus infections." Ware noted that the salivary
glands are a primary source of transmission for ...
Study: Well-known protein helps stem cells become secretory cells
... regulates secretion levels in the fruit fly's salivary
gland and its skin-like outer layer.
Described ... of events leading to secretion in the fruit fly's salivary
gland and epidermis, its skin-like outer layer. ... a graduate student, to focus on secretion in the salivary
gland, the largest glandular organ in the fruit ...
Biomarkers isolated from saliva successfully predict oral and breast cancer
... that such biomarkers found in saliva, called salivary
transcriptomes, can be exploited for robust, ... predictive power of 95 percent by using only the salivary
transcriptome samples and 88 percent by using ... cell carcinomas," said Wong. "For oral cancer, salivary
transcriptome has a slight edge of that of serum ...
Researchers use multiphoton microscopy to watch chromosomes in action
... in living cells.
Yao used multiphoton microscopy (MPM) to image living salivary
gland tissue of Drosophila (fruit flies). Unlike other methods, which ... crisp, clear images, even in thicker tissue samples like Drosophila salivary
The research was ultimately possible thanks to the unique ...
Gene that helps mosquitoes fight off malaria parasite identified
... As the parasite matures, it moves from the mosquito's midgut to its salivary
glands. Once in the salivary
glands, the Plasmodium can be injected into another human when the ...
Forsyth scientists find three bacteria associated with oral cancer
... genetic activity in oral tissues.
The current paper, "The salivary
Microbiota as a Diagnostic Indicator of Oral Cancer," reports on a study, ... as diagnostic indicators for OSCC. And, in fact, we found that elevated salivary
counts of the three bacteria correctly identified 80% of individuals with ...
Researchers identify protein crucial for survival of Lyme-disease bacterium
... the bacteria to replicate in large numbers and migrate to the tick's salivary
glands, where they are transmitted into animals or humans during the ... they should to sustain the numbers needed to move from the midgut to the salivary
glands. We don't understand the mechanism for that yet, and that will be ...
Simple home spit test to spot deadly pre-eclampsia
... levels of urate, a salt of uric acid, increased levels of which are thought to be due to impaired kidney excretion in pre-eclampsia.
urate test is simple, non-invasive, quick and cheap and can be done at any time. As a metabolic test independent of blood pressure, it may obviate ...
Multiple malaria infection inhibits spread of parasite
... stomach the gametes are released and fertilisation takes place. The parasite develops further until the final stage (the sporozoite) in the salivary
gland. The sporozoite can be transmitted with the saliva to a person if he/she is bitten by this mosquito. There the parasite reproduces rapidly and ...
Scientists explore how complex organs develop from a simple bud
... delve into tubulogenesis ?a process that is intimately tied to branching morphogenesis. Another contains research aimed at helping patients whose salivary
glands have been injured by radiation therapy or autoimmune rejection. An investigation into the morphogenesis of the prostate gland and seminal ...
Three-dimensional, miniature endoscope opens new diagnostic possibilities
... and minimize tissue damage," Tearney adds. "The device's size and flexibility should allow safer navigation through such delicate structures as the salivary
ducts, the fallopian tubes and the pancreatic duct. Fetal and pediatric procedures may also benefit from this tool. Eventually, SEE could give rise ...
Malaria vaccine prompts victims' immune system to eliminate parasite from mosquitoes
... mosquito gut, after which the parasite imbeds itself in the gut lining. There, it passes through discrete stages, before migrating to the insect's salivary
glands, where it is passed on to the next host through a mosquito bite.
The protein Pfs25 (Plasmodium falciparum surface protein 25) is found ...
New understanding of parasite cell structures may provide treatments for serious tropical diseases
... Africa. The parasite is transmitted to humans through the bite of the tsetse fly, in which the trypanosome transfers from the mid-gut to the salivary
glands where it enters the human bloodstream when the fly bites.
"We found that putting these cells under stress similar to that initially ...
'Banana-jawed' fossil mammal linked to rare sound-producing skill
"Our team had long speculated on the cavity's purpose, " Simons said. "One idea we proposed, for example, was that the chamber contained enlarged salivary
"Our current findings narrow down the possibilities," he said. "Among the most plausible explanations is that the hollow jaw was a ...
Researchers discover how malaria parasite disperses from red blood cells
... species of the parasite Plasmodium, the most common and deadly of which is Plasmodium falciparum. P. falciparum spends part of its life cycle in the salivary
glands of mosquitoes and is transmitted to human beings through the bite of infected mosquitoes. The parasite infects red blood cells. Called a ...
Visceral Leishmaniasis: Successful Vaccine Trial In Dogs
... Leishmania infantum. A flagellate protozoan, it uses as vector an insect resembling a midge, the sand fly, colonizing the intestine and then the salivary
glands. The female insect feeds on mammals?blood. It can thus pass the parasite on to humans by a single bite. Once in the blood stream, L. infantum ...
Researchers find first evidence of venom system in extinct mammal
... exists, said Craig Scott, a PhD student at the U of A and co-author of the paper in Nature.
Currently, there are two types of living mammals with salivary
venom-injecting capabilities: the Caribbean Solenodon (found primarily in Cuba) and the North American short-tailed shrew.
The fossil that Fox's ...
Disease diagnosis, biodefense among UH chemical research projects
... in lowering blood pressure, treating cancer and increasing oxygen absorption in lung tissue. Czernuszewicz's research is focused on the roles of salivary
nitrophorins in storing and releasing NO and binding histamine by using resonance Raman spectroscopic techniques as a probe of molecular structure. ...