As artificial intelligence (AI) permeates the healthcare industry, analytics leaders must ensure that AI remains ethical and beneficial to all patient populations. In absence of a formal regulatory or governing body to enforce AI standards, it’s up to healthcare professionals to safeguard ethics in healthcare AI.The potential for AI’s use in support of the pandemic response can have enormous payoffs. However, ensuring its ethical implementation may prove challenging if healthcare professionals are not familiar with the accuracy and limitations of AI-generated recommendations. Understanding how data scientists calculate algorithms, what data they use, and how to interpret it is critical to using AI in a meaningful and ethical manner to improve care delivery. By adhering to best practices for healthcare AI, health systems can guard against bias, ensure patient privacy, and maximize efficiencies while assisting humanity.