- INTRODUCTION TO THE PHARMACOLOGY COURSE.
- PHARMACODYNAMICS: Mechanisms of action of drugs. Use of omic technology for the study of drug efficacy and toxicity.
- Pharmacokinetics: Chemical-physical properties of drugs, Absorption, Distribution, Metabolism, Elimination. The main pharmacokinetic parameters. Therapeutic drug monitoring. Variability factors of drug response. Abnormal responses to drug administration. Role of genetics and epigenetics. Definition of equivalent or generic medicine.
- CELLULAR AND MOLECULAR PHARMACOLOGY: The pharmacology of systems. Receptors and signal transduction. Classes of receptors. Ionic transport. Transmission systems (cholinergic, catecholaminergic, serotonergic, histaminergic, purinergic, excitatory amino acids, inhibitory amino acids, opioid peptides, nitrous neuropeptides and arachidonic acid). Mechanisms of cellular interaction through the production of extracellular vesicles. Use of transgenic animal models for understanding the mechanism of action of drugs and their toxicity.
- INFLAMMATION DRUGS: Non-steroidal anti-inflammatory drugs. Steroid anti-inflammatory drugs. Gold salts, Penicillamine, Synthetic Antimalarials, Sulfasalazine. Biological drugs.
- PHARMACOLOGY OF THE IMMUNE SYSTEM: Immunostimulants and Immunosuppressants.
- CARDIOVASCULAR AND BLOOD SYSTEMS DRUGS: Antihypertensive drugs. Drugs for the treatment of ischemic heart disease. Heart failure drugs. Drugs for the treatment of cardiac arrhythmias. Drugs for cardiovascular risk prevention. Pharmacological treatment of vasculopathies. Hemostasis drugs. Antianemic drugs.
–DRUGS for renal system: Drugs for the treatment of alterations in hydro-electrolyte exchange