There is a factor in MS that is often misunderstood or more likely overlooked because of the language used.
Skull design in European decent people is different structurally than other skulls. The spaces and position of the brain within the skull predisposes it problems related to fluid flow and contact between the brain and skull at the skull base.
This is where Dr. Flanagan is second to none in his understanding of issues found in de-generative diseases such as MS.
The fluid flows are different with ethnicity. The shapes and passages are different and for this reason for instance the MS form Devics Disease is more common in Asian decent people whereas there is more Optic involvement with African design of skulls.(Correct me if I got that wrong please Dr. F, memory fade).This is well documented yet overlooked in understanding the fluid flows of blood and CSF.
When there are the added malformations within veins, mainly valves then there an increase of causation of diseases that are associated with brain flow of blood and CSF.
There is a lot of information that needs to be cross referenced and then discussed in the context of MS and each of the other de-generative diseases.
Keep thinking and talking