Doobie, Doobie, Do
Proponents of medical marijuana argue that it can be a safe and effective treatment for the symptoms of cancer, AIDS, multiple sclerosis, pain, glaucoma, epilepsy, and other conditions. They cite dozens of peer-reviewed studies, prominent medical organizations, major government reports, and the use of marijuana as medicine throughout world history. We investigated several organizations and research information on the subject, here are excerpts from the NIH and National Institute on Drug Abuse.
What are cannabinoids?
Cannabinoids are chemicals related to delta-9-tetrahydrocannabinol (THC), marijuana’s main mind-altering ingredient that makes people "high." The marijuana plant contains more than 100 cannabinoids. Scientists as well as illegal manufacturers have produced many cannabinoids in the lab. Some of these cannabinoids are extremely powerful and have led to serious health effects when misused
How cannabinoids may be useful as medicine?
Currently, the two main cannabinoids from the marijuana plant that are of medical interest are THC and CBD. THC can increase appetite and reduce nausea. THC may also decrease pain, inflammation (swelling and redness), and muscle control problems. Unlike THC, CBD is a cannabinoid that doesn't make people "high." It may be useful in reducing pain and inflammation, controlling epileptic seizures, and possibly even treating mental illness and addictions.
Many researchers, including those funded by the National Institutes of Health (NIH), are continuing to explore the possible uses of THC, CBD, and other cannabinoids for medical treatment.
For instance, recent animal studies have shown that marijuana extracts may help kill certain cancer cells and reduce the size of others. Evidence from one cell culture study with rodents suggests that purified extracts from whole-plant marijuana can slow the growth of cancer cells from one of the most serious types of brain tumors. Research in mice showed that treatment with purified extracts of THC and CBD, when used with radiation, increased the cancer-killing effects of the radiation.8
Scientists are also conducting preclinical and clinical trials with marijuana and its extracts to treat symptoms of illness and other conditions, such as:
· diseases that affect the immune system, including:
· multiple sclerosis (MS), which causes gradual loss of muscle control
· substance use disorders
· mental disorders
CBD and Childhood Epilepsy
There is growing interest in the marijuana chemical cannabidiol (CBD) to treat certain conditions such as childhood epilepsy, a disorder that causes a child to have violent seizures. Therefore, scientists have been specially breeding marijuana plants and making CBD in oil form for treatment purposes. These drugs aren't popular for recreational use because they aren't intoxicating.
Cannabis and Arthritis
A study published in the journal Rheumatology from Dr. Sheng-Ming Dai of China’s Second Military Medical University found that CB2 receptors are found in unusually high levels in the joint tissue of arthritis patients. The use of cannabis is shown to fight inflammation in the joints by activating the pathways of CB2 receptors.
Canadian researcher Dr. Jason McDougall, a professor of pharmacology and anesthesia at Dalhousie University in Halifax, has undertaken a new study to find out if medical marijuana can help repair arthritic joints and relieve pain. The study is supported by the Arthritis Society and is awarding a grant for a comprehensive, three-year study to investigate if cannabis is not just dampening the pain in the brain, but also working to fight inflammation and repair the joint itself.
When asked to describe the nerves of an arthritis sufferer, McDougall told CBC Radio’s Information Morning the following information:
“[The nerves are like] wires that have been stripped of their coating. They’re all bare, they’re all raw and responsible for feeling a lot of pain. What we hypothesize is that by locally administering these cannabis-like molecules to those nerves, we’d actually be able to repair them and reduce the pain of arthritis.”
McDougall’s research is focused on non-psychoactive cannabinoids, but so far, his findings has shown that cannabis molecules can attach themselves to nerve receptors and control the firing of pain signals in the joint. Indeed, it’s been proven in certain anecdotal circumstances, such as the case of Katie Marsh of Madawaska, Maine. A sufferer of rheumatoid arthritis, she was on a prescription of prednisone and antibiotics and was encouraged by her doctors to try disease-modifying anti-rheumatic drugs (DMARDS), but the side effects were severe enough that she sought a natural way to ease her pain and swollen joints.
After seeking the advice of a physician that specializes in dietary cannabis, Marsh began juicing raw cannabis, blending it into a smoothie and consuming the whole raw plant. She began to see results almost immediately — within days, Marsh was off the prednisone and even pain killers. After 11 months of regular cannabis juicing, her condition is in remission.
From : https://www.leafly.com/news/science-tech/the-medical-minute-can-cannabis-help-repair-arthritic-joints
For further information and studies on the above and more, you can go to the National Institute of Health (NIH) and o