The LifeOne Formula – Formulation
and Immune Enhancing Effects
Cancer rates increase
when the immune system is suppressed from immunodeficiency
diseases. Children with immunodeficiency diseases have
an increased rate of lymphoma, leukemia and Hodgkin’s
disease. HIV positive patients with immunosuppression
have many types of cancer including Kaposi’s sarcoma,
non-Hodgkin’s lymphoma, cervical cancer, and Hodgkin’s
disease. Organ transplant patients and autoimmune disease
patients have an increased incidence of cancer due to
the use of immunosuppressive drugs. Researchers believe
the immune system plays an important role in prevention
of cancer by recognizing, and destroying cancer cells.
The use of natural compounds in the treatment of cancer
and AIDS is growing throughout the world. Most of these
compounds have low toxicity and benefit the whole patient.
immune system is amazingly complex. For ease of description,
it can be divided into two parts; humoral activity,
concerned primarily with production of antibodies,
and cellular immunity, involving the interaction of
multiple cells that process information, recognize
“self” and “other”, and effectively destroy foreign
regards to HIV infection, we are primarily concerned
with immune cells and proteins coating the outside
of the cells and proteins coating the outside of the
cells which are the target of the HIV virus. This
protein, CD4, is on several cells of the immune system.
cell with the highest concentration of CD4 is named
the CD4+ T cell. The CD8+ cell is also rich in CD4
CD4+ cell is the primary target of HIV but all the
other cells exhibiting the CD4 protein are also adversely
primary function of the CD4+ cell is as a helper cell
that facilitates the functions of many other cells
of the immune system.
cells are the NK, natural killer cells, which recognize
and destroy cells presented to them that are coated
with foreign proteins. They may also suppress immune
responses. Initially, in the acute HIV infection,
CD8+ cell numbers increase as the immune system is
activated. Also acutely, the number of CD8+ cells
may remain elevated or return to normal levels. Apparently,
overwhelmed by the sheer numbers of viral particles,
large populations of CD8+ cells simply disappear followed
by a decrease in absolute numbers of CD8+ T lymphocytes
as the disease enters the chronic phase.
cells are another subpopulation of NK cells with the
function of destroying foreign invaders.
of development or failure of function of one or more
of these T Cell subsets may result in immunodeficiency
or autoimmune diseases.
the immune system remains in a state of equilibrium,
becoming active when presented with an invading organism.
When the threat is cleared by an intact immune system,
it returns to a state of normalcy.
HIV infected immune system is chronically activated.
Chronic exposure of the immune system to a particular
viral invader over an extended period may ultimately
lead to an inability to sustain an adequate immune
response to that invader. Furthermore, the ability
of the immune system to respond to a broad spectrum
of viruses and other threats may be compromised if
the immune system is in a state of chronic activation.
John Boik states in
his book “Natural Compounds In
Cancer Therapy” that there are seven procancer
events in the development of cancer. These events are:
order for a product, whether it is a pharmaceutical or
a natural product, to be optimally effective it must inhibit
these seven procancer events. The actions that inhibit
these seven procancer events are:
of genetic instability
expression of genes
of genetic instability
of abnormal expression of genes
of abnormal signal transduction
of normal cell-to cell communication
of tumor angiogenesis
of invasion and metastasis
of the immune system
ESTROGEN, TESTOSTERONE and CANCER
There is a positive
correlation between the proliferation of cancer cells
and the production of insulin, sex hormones, and lactic
acid. As cancer cells proliferate, local inflammation
and chaotic cellular development occurs, which causes
a low-oxygen (hypoxic) environment. This local
hypoxic state causes the excess production of lactic
acid and inefficient utilization of glucose, which in
turn stimulates angiogenesis (new blood vessels) to
try to feed the area with more glucose and oxygen. The
cancer cells consume glucose at a rate 3 to 5 times
higher than normal cells. As cancer cells proliferate,
serum glucose levels increase causing an increase of
serum insulin levels. Insulin has also been shown in
cancer cell cultures to be a growth factor, which causes
proliferation of the cell growth. Inhibition of the
abnormal production of lactic acid and insulin is an
important aspect of any cancer treatment.
estrogen and testosterone, have shown to be a cancer
growth factor, not only for reproductive organs (breast,
prostate, and ovarian cancers), but for other types
of cancers (pancreatic, lymphatic, skin, kidney, colon
and lung cancers) as well. Normalizing of hormone production
is therefore an important objective of a cancer treatment.
COMPOUNDS, CANCER and HIV
A number of natural
compounds have been show to possess properties that
are useful in the treatment of cancer and HIV. Obviously
those compounds that have the greatest number of properties
that inhibit the seven procancer events would be the
most desirable and effective to use. Research has also
shown that inhibition of the seven procancer events
will also inhibit HIV virus proliferation by inhibiting
the virus absorption process, cell-to-cell fusion, virus
growth, virus transmission, and immune stimulation.
Compounds that have
been shown to have a broad effect in treating cancer
and HIV are:
flavonoid from the Passion Flower that has antioxidant
6 of the 7 procancer events
Tumor Necrosis Factor (TNF) cytotoxicity to cancer cells
abnormal hormone action, binds estrogen receptors, alters
steroid hormone metabolism, normalizes testosterone
and other androgen levels
HIV expression and invasion in cell cultures, inhibits
HIV-1 transactivation, exhibits anti –HIV activity
Chinese herbal mushroom with anticancer effects
stimulates the immune system
the cytotoxicity of natural killer cells
the invasion of cancer cells (metastasis and local proliferation)
4 of the 7 procancer events
survival rates in post chemotherapy cancer patients
and anti-viral agent for HIV therapy
is a phytochemical from cruciferous vegetables (broccoli,
Brussels sprouts, cabbage)
a strong anti-estrogen effect on cancer cells
adhesion, motility, and invasiveness of cancer cells
5 of the 7 procancer events
phenolic compound found in grapes
as an antioxidant
platelet aggregation and reduces inflammation
6 of the 7 procancer events
abnormal estrogen action
anti-HIV activity: inhibits viral replication and proliferation
as a potent antioxidant
cancer cell proliferation in vitro
metastasis in vivo
5 of the 7 procancer events
transactivation of type 1 human immunodeficiency virus
long terminal repeat. Tat is a protein secreted by the
HIV1-infected cells that may have additional action
on the pathogenesis of AIDS
flavonoid that induces cell apoptosis
Strong anti-inflammatory that stabilizes basophils
and mast cells
Reduces cholesterol and LDL
Inhibits 6 of the 7 procancer events
flavonoid containing epigallocatechin gallate (EGCG),
the primary anticancer agent
as an antioxidant
and in-vivo anticancer activity
6 of 7 procancer events
activities of HIV-1 transcripts
organic form of selenium, which is better utilized by
Acts as an antioxidant
Inhibits 6 of the 7 procancer events
In-vitro and in-vivo studies show anticancer effects
Strong immune stimulator
Helps restore plasma selenium levels that are low in
cancer and HIV patients
Ingredients: Water, Liposomal Matrix (Lecithin
Complex with Phosphadidyl Choline and Phosphatidylserine),
Natural Flavors, Stevia, Sodium Benzoate and Potassium
Sorbate (as preservatives)
benefits cancer therapy resulting in lower dosages of
drugs or compounds. Many natural compounds need synergism
with other compounds to be effective against cancer,
HIV, and other immunodeficiency diseases. It is best
to use several natural compounds together in a mixture
to enhance the synergetic action of each compound.
unique property of a liposomal delivery system is a
higher cellular uptake and a prolonged circulation of
therapeutic agents. Use of a liposomal delivery system
is essential to maximize the actions of natural compounds.
is apparent in reviewing the research that the proper
mixture of natural compounds applied at a therapeutic
level, combined with the appropriate delivery system,
can effectively allow your body to reverse the destructive
capacities of cancer, HIV, and other immunodeficiency
The Truth about Sodium Benzoate and LifeOne Formula
Sodium benzoate is a type of salt that occurs naturally in some foods but is more likely to be chemically produced and added as a food preservative. When it used as a preservative, sodium benzoate is typically added to foods in small amounts only. The FDA allows a maximum concentration of 0.1% as a preservative. Food may take on a bitter taste if more is added.
Sodium benzoate has been the subject of extensive experimentation: it has been tested in long term and short-term feeding experiments in man, dogs, and rats and mice. In one experiment in Germany, four generations of rats were continuously exposed to 0.05 or 1 percent sodium benzoate in their diet. Scientists did not observe any harmful effects on growth, life span, or internal organs. No tumors were detected. All evidence points to sodium benzoate as a safe preservative, except for rare instances of allergic reaction. It also needs to be noted that this sodium benzoate was not combined with acidic food or ascorbic acid. It is this failure in experimentation that is causing such widespread concern of its use. Even in much longer term studies it has been found safe. That is because benzoate is a natural metabolite of the body. It is when the pH surrounding this preservative is low (acidic) that the production of benzene and other difficulties take place.
The reason sodium benzoate is listed in the ingredients of numerous foods is because it works well at killing a wide variety of bacteria, yeast and fungi. You will almost always see it used as a preservative in foods with a high acid content. This is because sodium benzoate will only work when the pH balance of the foods or drinks is less than 3.6. Because it becomes active only at a low pH it is most commonly used un foods such as most sodas, vinegar, fruit juice, and in mixed ingredients like salad dressing. It is also used to stop the fermentation process in wines.
Sodium benzoate naturally occurs in several natural fruits such as apples, plums and cranberries. A few sweet spices contain small amounts of sodium benzoate, including cloves and cinnamon. The presence of sodium benzoate in these foods does not necessarily act to preserve them. Many contain levels higher than the FDA recommended concentration of 0.1%.
The most common fear is that the use of sodium benzoate with citric acid or ascorbic acid, (vitamin C), can produce benzene which is highly carcinogenic, and may cause genetic mutations. This is true and I was one of the first to make the same complaint. It needs to be remembered however that this only occurs when the pH is below 3.8, which is acidic. In LifeOne it never reaches that pH nor anywhere near it. For this reason and others, no benzene is produced.
We are often asked why we do not use other preservatives like citric acid. The answer is simple, but the implications are too numerous and complicated to go into in this short article. We do not use citric acid and other like preservatives because it would change the pH of LifeOne and for several reasons that is unacceptable. LifeOne is kept very close to the normal pH of blood at just over 7.
Since LifeOne uses an extremely small amount of sodium benzoate, some have questioned its safety. Whether you believe the charges that are currently being thrown about concerning its safety, knowledge of the how and why it is used is a legitimate question.
1. Though the FDA sets the limit of sodium benzoate at 0.1%, LifeOne formula uses a minute fraction of that amount.
2. Since sodium benzoate is only activated at a pH of less than 3.8, it can never become active in LifeOne because LifeOne has a pH of over 7.
3. The sodium is released in the water phase and does not react with anti oxidants. Since it cannot react with the antioxidants it cannot produce benzene.
4. If you doubled the dose of LifeOne you would be getting less sodium benzoate than you would in an organic apple.
5. Since LifeOne is often stored for periods of times in warm climates without the benefit of refrigeration and because many USA users of LifeOne may leave their bottles out on the counter for days at a time it is necessary to be as safe as possible to see that the bottles do not become contaminated by as wide a range of bacteria, molds, and fungi as possible. By being added in a miniscule amount in the water phase of production we are able to accomplish this without jeopardizing the users’ health in any way.
6. It prevents oxidation that starts a chain reaction between glycerin and or oxidative B's into aldehydes like Octanal C8 H16 O, Decanal C11 H22 O which can be extremely dangerous aldehydes when ingested.
7. 1954 Dr. W.H. Stein reported in the Journal of the American Chemical Society that benzoate is a natural metabolite of the human body through endogenous formation of benzoate through the phenylalanine-tyrosine pathway. In other words we produce it naturally in our own bodies’, so fear of the substance needs to be tempered with knowledge of its use and properties.
8. When compared to the possibility of contracting bacterium clostridium botulinum or other serious bacteria, molds or fungi it seems much safer than doing nothing, or ruining the product for the properties that make it so effective.
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the same day.
LifeOne Formula by LifeOne Sales, LLP are all natural
Due to the nature of the LifeOne Formula, all sales
No Returns can be accepted on the LifeOne Formula
once the products reach your shipping address.