  We argue that the diphoton excess recently reported by ATLAS and CMS can be
explained, along with several anomalies seen in the flavor sector, in models
where a Standard-Model singlet scalar resonance with mass $M \approx 750$ GeV
is produced in gluon fusion via loops containing a scalar color- triplet
leptoquark $\phi$. For a leptoquark mass $M_\phi \lesssim$ 1 TeV, the
production cross section is naturally in the 10 fb range. A large $S \to \gamma
\gamma$ branching ratio can be obtained by coupling the scalar S to new
color-singlet fermions $\chi$ with electroweak scale masses, which can be part
of an $SU(2)_L$ multiplet, whose neutral component has the right mass and
quantum numbers to be a dark matter candidate. Our model reveals a connection
between flavor anomalies, the nature of dark matter and a new scalar, which
acts as a mediator to the dark sector. The loop-mediated decay $S \to
\tau^+\tau^-$ could be a striking signature of this model.
