  We propose a new kind of axion model derived from the Grand Unified Theory
(GUT) based on $SU(5)\times U(1)_{\rm PQ}$. We demonstrate that, given a
certain charge assignment and potential flavor models, the axion is naturally
hadrophobic and provides a novel explanation for the required condition using
isospin symmetry. This axion can be the QCD axion that solves the strong CP
problem. Furthermore, to satisfy the limit on the axion-electron coupling from
the tip of the red giant branch, we impose the condition of electrophobia to
determine a possible PQ charge assignment consistent with GUT. We then discuss
the possibility that the hadrophobic and electrophobic axion serves as an
inflaton and dark matter, as in the ALP miracle scenario. Interestingly, in the
viable parameter region, the strong CP phase must be suppressed, providing
another solution to the strong CP problem. This scenario is intimately linked
to flavor physics, dark matter searches, and stellar cooling. Detecting such an
axion with peculiar couplings in various experiments would serve as a probe for
GUT and the origin of flavor.
