  Suppose $G$ is a finite group. The set of all centralizers of $2-$element
subsets of $G$ is denoted by $2-Cent(G)$. A group $G$ is called
$(2,n)-$centralizer if $|2-Cent(G)| = n$ and primitive $(2,n)-$centralizer if
$|2-Cent(G)| = |2-Cent(\frac{G}{Z(G)})| = n$, where $Z(G)$ denotes the center
of $G$. The aim of this paper is to present the main properties of
$(2,n)-$centralizer groups among them a characterization of $(2,n)-$centralizer
and primitive $(2,n)-$centralizer groups, $n \leq 9$, are given.
