  We reappraise the viability of asymmetric dark matter (ADM) realized as a
Dirac fermion coupling dominantly to the Standard Model fermions. Treating the
interactions of such a DM particle with quarks/leptons in an
effective-interactions framework, we derive updated constraints using mono-jet
searches from the Large Hadron Collider (LHC) and mono-photon searches at the
Large Electron-Positron (LEP) collider. We carefully model the detectors used
in these experiments, which is found to have significant impact. The constraint
of efficient annihilation of the symmetric part of the ADM, as well as other
observational constraints are synthesized to produce a global picture.
Consistent with previous work, we find that ADM with mass in the range $1-100$
GeV is strongly constrained, thus ruling out its best motivated mass range.
However, we find that leptophilic ADM remains allowed for $\gtrsim 10$ GeV DM,
including bounds from colliders, direct detection, and stellar heating. We
forecast that the Future Circular Collider for electron-positron collisions
(FCC-ee) will improve sensitivity to DM-lepton interactions by almost an order
of magnitude.
