  Migrating cells choose their preferential direction of motion in response to
different signals and stimuli sensed by spanning their external environment.
However, the presence of dense fibrous regions, lack of proper substrate, and
cell overcrowding may hamper cells from moving in certain directions or even
from sensing beyond regions that practically act like physical barriers. We
extend the non-local kinetic model proposed by Loy and Preziosi (2019) to
include situations in which the sensing radius is not constant, but depends on
position, sensing direction and time as cells' behavior might be determined on
the basis of information collected before reaching physically limiting
configurations. We analyze how the actual possible sensing of the environment
influences the dynamics by recovering the appropriate macroscopic limits and by
integrating numerically the kinetic transport equation.
