  Pool sequencing is an efficient method for capturing genome-wide allele
frequencies from multiple individuals, with broad applications such as studying
adaptation in Evolve-and-Resequence experiments, monitoring of genetic
diversity in wild populations, and genotype-to-phenotype mapping. Here, we
present grenedalf, a command line tool written in C++ that implements common
population genetic statistics such as $\theta$, Tajima's D, and FST for Pool
sequencing. It is orders of magnitude faster than current tools, and is focused
on providing usability and scalability, while also offering a plethora of input
file formats and convenience options.
