  In the last years several proof of principle experiments have demonstrated
the advantages of quantum technologies respect to classical schemes. The
present challenge is to overpass the limits of proof of principle
demonstrations to approach real applications. This letter presents such an
achievement in the field of quantum enhanced imaging. In particular, we
describe the realization of a sub-shot noise wide field microscope based on
spatially multi-mode non-classical photon number correlations in twin beams.
The microscope produces real time images of 8000 pixels at full resolution, for
(500micrometers)2 field-of-view, with noise reduced to the 80% of the shot
noise level (for each pixel), suitable for absorption imaging of complex
structures. By fast post-elaboration, specifically applying a quantum enhanced
median filter, the noise can be further reduced (less than 30% of the shot
noise level) by setting a trade-off with the resolution, demonstrating the best
sensitivity per incident photon ever achieved in absorption microscopy.
