  In this article I study the distribution of spiral galaxies in the Sloan
Digital Sky Survey (SDSS) to investigate whether the universe has an overall
handedness. A preference for spiral galaxies in one sector of the sky to be
left-handed or right-handed spirals would indicate a preferred handedness. The
SDSS data show a strong signal for such an asymmetry with a probability of
occurring by chance ~3.0 x 10-4. The asymmetry axis is at (RA,Dec) ~(202d,25d)
with an uncertainty ~15d. The axis appears to be correlated with that of the
quadrupole and octopole moments in the WMAP microwave sky survey, an unlikely
alignment that has been dubbed "the axis of evil". Our Galaxy is aligned with
its spin axis within 8.4d of this spiral axis.
