  Recent experimental studies suggest that wet-dry cycles and coexisting phases
can each strongly alter chemical processes. The mechanisms of why and to which
degree chemical processes are altered when subject to evaporation and
condensation are unclear. To close this gap, we developed a theoretical
framework for non-dilute chemical reactions subject to non-equilibrium
conditions of evaporation and condensation. We find that such conditions can
change the half-time of the product's yield by more than an order of magnitude,
depending on the substrate-solvent interaction. We show that the cycle
frequency strongly affects the chemical turnover when maintaining the system
out of equilibrium by wet-dry cycles. There exists a resonance behavior in the
cycle frequency where the turnover is maximal. This resonance behavior enables
wet-dry cycles to select specific chemical reactions suggesting a potential
mechanism for chemical evolution in prebiotic soups at early Earth.
