  In biochemical signaling, information is often encoded in oscillatory
signals. However, the advantages of such a coding strategy over an amplitude
encoding scheme of constant signals remain unclear. Here we study the dynamics
of a simple model gene promoter in response to oscillating and constant
transcription factor signals. We find that in biologically-relevant parameter
regimes an oscillating input can produce a more constant protein level than a
constant input. Our results suggest that oscillating signals may be used to
minimize noise in gene regulation.
