  Unique labeling of chiral stereo-centers must include their handedness. The
conventional method that has been developed to do this was originated by three
chemists: R.S. Cahn, C. Ingold, and V. Prelog (CIP) and is formally known as
R,S nomenclature. It requires knowledge of the spatial absolute configuration
of that center. Traditionally, experimental methods of extracting handedness go
through the absolute configuration and only then through the application of the
CIP convention. Here we show that a direct experimental method of determination
of the natural handedness by the polarization of tunneling electrons is almost
always compatible with the CIP convention. By the sole use of symmetry
arguments we show that the chiral molecule symmetry withdraws the need of fine
structure splitting. As a consequence, the polarization of electrons tunneling
through the molecular electric dipole direction uniquely determines their
handedness. The symmetry breaking argument that induces lack of fine-structure
splitting eliminates the need for a precise value of the spin-orbit
interaction.
