  For glucose electrochemical sensors, a comprehensive electronics interface is
designed and constructed in 0.18 um, CMOS process technology, and 1.5 V supply
voltage. This interface includes a programmable readout amplifier and bandgap
reference voltage potentiostat circuit. The programmable transimpedance
amplifier (PTIA), the proposed readout circuit, provides a large dynamic range
and low noise. The overall transimpedance increase for the PTIA is 17.3-50.5
kohm. For an input current range of 4.2-180 uA, the PTIA response has a linear
output voltage range of 0.55-1.44 V. The output rms noise value is calculated
to be 5.101 Vrms, and the overall power consumption of the design is 2.33 mW.
The THD percentage spans from 7.6 to 10.2 in the current range mentioned above.
All bandgap reference voltage potentiostat measurements are made using the
reference potential of 0.6 V. The working electrode was a glassy carbon
electrode (GCE) loaded with a CuO/Cu0:76CO2:25O4 (copper cobaltite) coating. An
electrochemical glucose sensing setup has been used to measure glucose
concentrations between 1 and 10 mM, and an emulated circuit has been used to
verify the viability of the proposed glucose sensing design. The suggested
glucose sensor architecture has a total size of 0.0684 mm2.
