  A loop $(Q,\cdot,\backslash,/)$ is called a middle Bol loop if it obeys the
identity $x(yz\backslash x)=(x/z)(y\backslash x)$. To every right (left) Bol
loop corresponds a middle Bol loop via an isostrophism. In this paper, the
structure of the holomorph of a middle Bol loop is explored. For some special
types of automorphisms, the holomorph of a commutative loop is shown to be a
commutative middle Bol loop if and only if the loop is a middle Bol loop and
its automorphism group is abelian and a subgroup of both the group of middle
regular mappings and the right multiplication group. It was found that
commutativity (flexibility) is a necessary and sufficient condition for
holomorphic invariance under the existing isostrophy between middle Bol loops
and the corresponding right (left) Bol loops. The right combined holomorph of a
middle Bol loop and its corresponding right (left) Bol loop was shown to be
equal to the holomorph of the middle Bol loop if and only if the automorphism
group is abelian and a subgroup of the multiplication group of the middle Bol
loop. The obedience of an identity dependent on automorphisms was found to be a
necessary and sufficient condition the left combined holomorph of a middle Bol
loop and its corresponding left Bol loop to be equal to the holomorph of the
middle Bol loop.
