  A common problem in large-scale data analysis is to approximate a matrix
using a combination of specifically sampled rows and columns, known as CUR
decomposition. Unfortunately, in many real-world environments, the ability to
sample specific individual rows or columns of the matrix is limited by either
system constraints or cost. In this paper, we consider matrix approximation by
sampling predefined \emph{blocks} of columns (or rows) from the matrix. We
present an algorithm for sampling useful column blocks and provide novel
guarantees for the quality of the approximation. This algorithm has application
in problems as diverse as biometric data analysis to distributed computing. We
demonstrate the effectiveness of the proposed algorithms for computing the
Block CUR decomposition of large matrices in a distributed setting with
multiple nodes in a compute cluster, where such blocks correspond to columns
(or rows) of the matrix stored on the same node, which can be retrieved with
much less overhead than retrieving individual columns stored across different
nodes. In the biometric setting, the rows correspond to different users and
columns correspond to users' biometric reaction to external stimuli, {\em
e.g.,}~watching video content, at a particular time instant. There is
significant cost in acquiring each user's reaction to lengthy content so we
sample a few important scenes to approximate the biometric response. An
individual time sample in this use case cannot be queried in isolation due to
the lack of context that caused that biometric reaction. Instead, collections
of time segments ({\em i.e.,} blocks) must be presented to the user. The
practical application of these algorithms is shown via experimental results
using real-world user biometric data from a content testing environment.
