  Multi-Conjugate Adaptive Optics systems based on sodium Laser Guide Stars may
exploit Natural Guide Stars to solve intrinsic limitations of artificial
beacons (tip-tilt indetermination and anisoplanatism) and to mitigate the
impact of the sodium layer structure and variability. The sodium layer may also
have transverse structures leading to differential effects among Laser Guide
Stars. Starting from the analysis of the input perturbations related to the
Sodium Layer variability, modeled directly on measured sodium layer profiles,
we analyze, through a simplified end-to-end simulation code, the impact of the
low/medium orders induced on global performance of the European Extremely Large
Telescope Multi-Conjugate Adaptive Optics module MAORY.
