  Cosmic-ray observations provide a powerful probe of dark matter annihilation
in the Galaxy. In this paper we derive constraints on heavy dark matter from
the recent precise AMS-02 antiproton data. We consider all possible
annihilation channels into pairs of standard model particles. Furthermore, we
interpret our results in the context of minimal dark matter, including
higgsino, wino and quintuplet dark matter. We compare the cosmic-ray antiproton
limits to limits from $\gamma$-ray observations of dwarf spheroidal galaxies
and to limits from $\gamma$-ray and $\gamma$-line observations towards the
Galactic center. While the latter limits are highly dependent on the dark
matter density distribution and only exclude a thermal wino for cuspy profiles,
the cosmic-ray limits are more robust, strongly disfavoring the thermal wino
dark matter scenario even for a conservative estimate of systematic
uncertainties.
