  A fundamental design rule that nature has developed for biological machines
is the intimate correlation between motion and function. One class of
biological machines is molecular motors in living cells, which directly convert
chemical energy into mechanical work. They coexist in every eukaryotic cell,
but differ in their types of motion, the filaments they bind to, the cargos
they carry, as well as the work they perform. Such natural structures offer
inspiration and blueprints for constructing DNA-assembled artificial systems,
which mimic their functionality. In this article, we describe two groups of
cytoskeletal motors, linear and rotary motors. We discuss how their artificial
analogues can be built using DNA nanotechnology. Finally, we summarize ongoing
research directions and conclude that DNA origami has a bright future ahead.
