  In microvascular transport, where both blood and drug carriers are involved,
plasma skimming has a key role on changing hematocrit level and drug carrier
concentration in capillary beds after continuous vessel bifurcation in the
microvasculature. While there have been numerous studies on modeling the plasma
skimming of blood, previous works lacked in consideration of its interaction
with drug carriers. In this paper, a generalized plasma skimming model is
suggested to predict the redistributions of both the cells and drug carriers at
each bifurcation. In order to examine its applicability, this new model was
applied on a single bifurcation system to predict the redistribution of red
blood cells and drug carriers. Furthermore, this model was tested at
microvascular network level under different plasma skimming conditions for
predicting the concentration of drug carriers. Based on these results, the
applicability of this generalized plasma skimming model is fully discussed and
future works along with the model's limitations are summarized.
