  Hyperfine structure lines of highly-charged ions may open a new window in
observations of hot rarefied astrophysical plasmas. In this paper we discuss
spectral lines of isotopes and ions abundant at temperatures 10^5-10^7 K,
characteristic for warm-hot intergalactic medium, hot interstellar medium,
starburst galaxies, their superwinds and young supernova remnants. Observations
of these lines will allow to study bulk and turbulent motions of the observed
target and will broaden the information about the gas ionization state,
chemical and isotopic composition.
  The most prospective is the line of the major nitrogen isotope having
wavelength 5.65 mm (Sunyaev and Churazov 1084). Wavelength of this line is
well-suited for observation of objects at z=0.15-0.6 when it is redshifted to
6.5-9 mm spectral band widely-used in ground-based radio observations, and, for
example, for z>=1.3, when the line can be observed in 1.3 cm band and at lower
frequencies. Modern and future radio telescopes and interferometers are able to
observe the absorption by 14-N VII in the warm-hot intergalactic medium at
redshifts above z=0.15 in spectra of brightest mm-band sources. Sub-millimeter
emission lines of several most abundant isotopes having hyperfine splitting
might also be detected in spectra of young supernova remnants.
