  Contrary to common belief, there are perspectives for generalizing the notion
of positive and negative frequency in minisuperspace quantum cosmology, even
when the wave equation does not admit symmetries. We outline a strategy in
doing so when the potential is positive. Also, an underlying unitarity
structure shows up. Starting in the framework of the Klein-Gordon type
quantization, I am led to a result that relies on global features on the model,
and that is possibly related to structures encountered in the refined algebraic
quantization scheme.
