  Cosmic Ray nuclei in the energy range 100 MeV/nuc - 100 GeV/nuc provide
crucial information about the physical properties of the Galaxy. They can also
be used to answer questions related to astroparticle physics. This paper
reviews the results obtained in this direction, with a strong bias towards the
work done by the authors at {\sc lapth}, {\sc isn} and {\sc iap}. The
propagation of these nuclei is studied quantitatively in the framework of a
semi-analytical two-zone diffusion model taking into account the effect of
galactic wind, diffuse reacceleration and energy losses. The parameters of this
model are severely constrained by an analysis of the observed B/C ratio. These
constraints are then used to study other species such as radioactive species
and light antinuclei. Finally, we focus on the astroparticle subject and we
study the flux of antiprotons and antideuterons that might be due to neutralino
annihilations or primordial black hole evaporation. The question of the spatial
origin of all these species is also addressed.
