  COVID-19 has quickly spread across the globe, becoming a pandemic. This
disease has a variable impact in different countries depending on their
cultural norms, mitigation efforts and health infrastructure. In India, a
majority of people rely upon traditional Indian medicine to treat human
maladies due to less-cost, easier availability and without any side-effect.
These medicines are made by herbal plants. This study aims to assess the Indian
herbal plants in the pursuit of potential COVID-19 inhibitors using in silico
approaches. We have considered 18 extracted compounds of 11 different species
of these plants. Our calculated lipophilicity, aqueous solubility and binding
affinity of the extracted compounds suggest that the inhibition potentials in
the order; harsingar > aloe vera > giloy > turmeric > neem > ashwagandha > red
onion > tulsi > cannabis > black pepper. On comparing the binding affinity with
hydroxychloroquine, we note that the inhibition potentials of the extracts of
harsingar, aloe vera and giloy are very promising. Therefore, we believe that
these findings will open further possibilities and accelerate the works towards
finding an antidote for this malady.
