  We report the discovery of a large, sudden, and persistent increase in the
spin-down rate of B0540-69, a young pulsar in the Large Magellanic Cloud, using
observations from the Swift and RXTE satellites. The relative increase in the
spin-down rate of 36% is unprecedented for B0540-69. No accompanying change in
the spin rate is seen, and no change is seen in the pulsed X-ray emission from
B0540-69 following the change in the spin-down rate. Such large relative
changes in the spin-down rate are seen in the recently discovered class of
'intermittent pulsars', and we compare the properties of B0540-69 to such
pulsars. We consider possible changes in the magnetosphere of the pulsar that
could cause such a large change in the spin-down rate.
