  Optical tomographic cross-sectional images of biological samples were made
possible by interferometric imaging techniques such as Optical Coherence
Tomography (OCT). Owing to its unprecedented view of the sample, OCT has become
a gold standard, namely for human retinal imaging in the clinical environment.
In this Letter, we present Optical Incoherence Tomography (OIT): a completely
digital method extending the possibility to generate tomographic retinal
cross-sections to non-interferometric imaging systems such as en-face
AO-ophthalmoscopes. We demonstrate that OIT can be applied to different imaging
modalities using back-scattered and multiply-scattered light including systems
without inherent optical sectioning. We show that OIT can be further used to
guide focus position when the user is "blind" focusing, allowing precise
imaging of translucent retinal structures, the vascular plexuses and the
retinal pigment epithelium using respectively split detection, motion contrast,
and autofluorescence techniques.
