  A recent theoretical model predicts that the modification of quark
distributions in the nuclear medium (EMC effect) depends on the flavor of the
quarks. We investigate $W$-boson production in proton-nucleus collision as a
possible tool to test this theoretical prediction. Several experimental
observables in $W$ production sensitive to the flavor-dependent EMC effect are
identified. Calculations for these experimental observables at the RHIC and LHC
energies are presented using the recent flavor-dependent EMC model.
