  The paper discusses the features of the behavior of pion production cross
section as a function of the atomic mass of the target nucleus for the reaction
of fragmentation of the incident deuterons in the pions produced in the
so-called "twice-cumulative" kinematic region. A distinctive feature of the
twice-cumulative pions is that for their production the target nucleus must be
heavier than hydrogen. The simulation results show that the dependence of the
cross sections for pion production in the twice-cumulative region differs from
the analogous dependence for the cumulative region. The paper discusses the
reasons for such differences. In this work we present simulation results for
some models of nuclear structure on small nucleon-nucleon distances.
