  Oblique plane microscopy, OPM, is a form of lightsheet microscopy that
permits volumetric imaging of biological samples at high temporal and spatial
resolution. However, the imaging geometry of OPM, and related variants of light
sheet microscopy, distorts the coordinate frame of the presented image sections
with respect to real space coordinate frame in which the sample is moved to
navigate to regions of interest. This makes live viewing and practical
operation of such microscopes difficult. We present an open-source software
package that utilises GPU acceleration and multiprocessing to transform the
display of OPM imaging data in real time to produce live views that mimic that
produced by standard widefield microscopes. Image stacks can be acquired,
processed and plotted at rates of several Hz, making live operation of OPMs,
and similar microscopes, more user friendly and intuitive.
