  We report on studies of exclusive and inclusive semileptonic b -> ul\nu and b
-> cl\nu decays in 9.7 million B\barB events accumulated with the CLEO detector
in symmetric e^+e^- collisions produced in the Cornell Electron Storage Ring
(CESR). Various experimental techniques, including the inference of neutrino
candidates using the hermeticity of the CLEO detector and the study of spectral
moments, are used in conjunction with theoretical calculations to provide
estimates of the CKM matrix elements |V_ub| and |V_cb|.
