  In this position paper, a large group of interdisciplinary experts outlines
response strategies against the spread of SARS-CoV-2 in the winter of 2021/2022
in Germany. We review the current state of the COVID-19 pandemic, from
incidence and vaccination efficacy to hospital capacity. Building on this
situation assessment, we illustrate various possible scenarios for the winter,
and detail the mechanisms and effectiveness of the non-pharmaceutical
interventions, vaccination, and booster. With this assessment, we want to
provide orientation for decision makers about the progress and mitigation of
COVID-19.
