  Multi-line molecular observations are an ideal tool for a systematic study of
the physico-chemical processes in the Interstellar Medium (ISM), given the wide
range of critical densities associated with different molecules and their
transitions, and the dependencies of chemical reactions on the energy budget of
the system. Recently high spatial resolution of typical shock tracers - SiO,
HNCO, and CH3OH - have been studied in the potentially shocked regions in two
nearby galaxies: NGC 1068 (an AGN-host galaxy) (Huang et al., Astron.
Astrophys., 2022, 666, A102; Huang et al., in prep.) and NGC 253 (a starburst
galaxy) (K.-Y. Huang et al., arXiv, 2023, preprint, arXiv:2303.12685, DOI:
10.48550/arXiv.2303.12685). This paper is dedicated to the comparative study of
these two distinctively different galaxies, with the aim of determining the
differences in their energetics and understanding large-scale shocks in
dfferent types of galaxies.
