  It is well known that in low energy supersymmetry the ratio of the gaugino
mass to the gauge coupling squared, M/alpha, is renormalization group invariant
to one-loop. We present a systematic analysis of the corrections to this ratio,
including standard two-loop corrections from gauge and Yukawa couplings,
corrections due to an additional U(1)' gaugino, threshold corrections,
superoblique corrections, corrections due to extra matter, GUT and Planck scale
corrections, and ``corrections'' from messenger sectors with supersymmetry
breaking communicated via gauge-mediation. We show that many of these effects
induce corrections at the level of a few to tens of percent, but some could
give much larger corrections, drastically disrupting the renormalization group
extrapolation of the ratio to higher scales. Our analysis is essentially
model-independent, and therefore can be used to determine the ambiguities in
extrapolating the ratio in any given model between the weak scale and higher
scales.
