  We propose an entanglement criterion, specially designed for mixed states,
based on uncertainty relation and the Wigner-Yanase skew information. The
variances in this uncertainty relation does not involve any classical mixing
uncertainty, and thus turns out to be purely of quantum mechanical nature. We
show that any mixed entangled state can be characterized by our criterion. We
demonstrate its utility for several generalized mixed entangled state including
Werner states and it turns out to be stronger than any other known criterion in
identifying the correct domain of relevant parameters for entanglement. The
proposed criterion reduces to the Schrodinger-Robertson inequality for pure
states.
