  The role of hydrodynamic mixing in astrophysics is reviewed, emphasizing
connections with laser physics experiments and inertial confinement fusion
(ICF). Computer technology now allows two dimensional (2D) simulations, with
complex microphysics, of stellar hydrodynamics and evolutionary sequences, and
holds the promise for 3D. Careful validation of astrophysical methods, by
laboratory experiment, by critical comparison of numerical and analytical
methods, and by observation are necessary for the development of simulation
methods with reliable predictive capability. Recent and surprising results from
isotopic patterns in presolar grains, 2D hydrodynamic simulations of stellar
evolution, and laser tests and computer simulations of Richtmeyer-Meshkov and
Rayleigh-Taylor instabilities are discussed, and related to stellar evolution
and supernovae.
