  We investigate chemo-photothermal effects of gold nanorods (GNRs) coated
using mesoporous silica (mSiO2) loading doxorubicin (DOX). When the mesoporous
silica layer is embedded by doxorubicin drugs, a significant change in
absorption spectra enable to quantify the drug loading. We carry out
photothermal experiments on saline and livers of mice having GNRs@mSiO2 and
GNRs@mSiO2-DOX. We also inject the gold nanostructures into many
tumor-implanted mice and use laser illumination on some of them. By measuring
weight and size of tumors, the distinct efficiency of photothermal therapy and
chemotherapy on treatment is determined. We experimentally confirm the
accumulation of gold nanostructures in liver.
