  We investigate the breakdown of collinear factorization for non-inclusive
observables in hadron-hadron collisions. For pure QCD processes, factorization
is violated at the three-loop level and it has a structure identical to that
encountered previously in the case of super-leading logarithms. In particular,
it is driven by the non-commutation of Coulomb/Glauber gluon exchanges with
other soft exchanges. Beyond QCD, factorization may be violated at the two-loop
level provided that the hard subprocess contains matrix element contributions
with phase differences between different colour topologies.
