  We analyze the parameter space of the (mu > 0, A_0 = 0) CMSSM at large tan
beta with a small degree of non-universality originating from D-terms and
Higgs-sfermion splitting inspired by SO(10) GUT models. The effects of such
non-universalities on the sparticle spectrum and observables such as (g-2)_mu,
B(b -> X_s gamma), the SUSY threshold corrections to the bottom mass and
Omega_CDM h^2 are examined in detail and the consequences for the allowed
parameter space of the model are investigated. We find that even small
deviations to universality can result in large qualitative differences compared
to the universal case; for certain values of the parameters, we find, even at
low m_16, that radiative electroweak symmetry breaking fails as a consequence
of either |mu|^2 < 0 or m_(A^0)^2 < 0. We find particularly large departures
from the mSugra case for the neutralino relic density, which is sensitive to
significant changes in the position and shape of the A^0 resonance and a
substantial increase in the Higgsino component of the LSP. However, we find
that the corrections to the bottom mass are not sufficient to allow for Yukawa
unification.
