  This paper describes the COMBINE software package used for statistical
analyses by the CMS Collaboration. The package, originally designed to perform
searches for a Higgs boson and the combined analysis of those searches, has
evolved to become the statistical analysis tool presently used in the majority
of measurements and searches performed by the CMS Collaboration. It is not
specific to the CMS experiment, and this paper is intended to serve as a
reference for users outside of the CMS Collaboration, providing an outline of
the most salient features and capabilities. Readers are provided with the
possibility to run COMBINE and reproduce examples provided in this paper using
a publicly available container image. Since the package is constantly evolving
to meet the demands of ever-increasing data sets and analysis sophistication,
this paper cannot cover all details of COMBINE. However, the online
documentation referenced within this paper provides an up-to-date and complete
user guide.
