  X-ray data indicate that complexes of ribosomes with cognate and near cognate
tRNAs are very similar structurally, and this was the ground for a suggestion
that the ribosome discriminates correct codon-anticodon pair because of its
higher stability. Here an alternative explanation of kinetic proofreading is
suggested, and intramolecular oscillations in tRNAs play a keystone role in it.
Resonance of the oscillations allows the cognate codon-anticodon pair to be
conserved due to fast energy transfer to other part of the tRNA molecule. This
mechanism can potentially discriminate correct pair from an incorrect one even
if they have similar stabilities.
