  Cell division is an essential biological process, and regulation of cell
division is of relevance for many important fields of biology and medicine.
Introducing exogenous substances, such as nanoparticles, into the nucleus, has
been experimentally studied to regulate the division of cells. Herein we
considered this phenomenon from a general view of energetics. Through analyzing
the thermodynamics during the cell division process, we investigated the
optimal symmetry for cell division and the effect of nanoparticles on the
energy barriers. The presence of nanoparticles inside cell nucleus might arrest
cells before cytokinesis or other stages, thereby regulate the cell division.
