  Magnetic resonance fingerprinting (MRF) is one novel fast quantitative
imaging framework for simultaneous quantification of multiple parameters with
pseudo-randomized acquisition patterns. The accuracy of the resulting
multi-parameters is very important for clinical applications. In this paper, we
derived signal evolutions from the anomalous relaxation using a fractional
calculus. More specifically, we utilized time-fractional order extension of the
Bloch equations to generate dictionary to provide more complex system
descriptions for MRF applications. The representative results of phantom
experiments demonstrated the good accuracy performance when applying the
time-fractional order Bloch equations to generate dictionary entries in the MRF
framework. The utility of the proposed method is also validated by in-vivo
study.
