  Human-centricity is the core value behind the evolution of manufacturing
towards Industry 5.0. Nevertheless, there is a lack of architecture that
considers safety, trustworthiness, and human-centricity at its core. Therefore,
we propose an architecture that integrates Artificial Intelligence (Active
Learning, Forecasting, Explainable Artificial Intelligence), simulated reality,
decision-making, and users' feedback, focusing on synergies between humans and
machines. Furthermore, we align the proposed architecture with the Big Data
Value Association Reference Architecture Model. Finally, we validate it on
three use cases from real-world case studies.
