  We have studied the possible isospin corrections on the skewness and kurtosis
of net-baryon and net-charge fluctuations in the isospin asymmetric matter
formed in relativistic heavy-ion collisions at RHIC-BES energies, based on a
3-flavor polyakov-looped Nambu-Jona-Lasinio model. With typical
scalar-isovector and vector-isovector couplings leading to the splitting of $u$
and $d$ quark chiral phase transition boundaries and critical points, we have
observed dramatic isospin effects on the susceptibilities, especially those of
net-charge fluctuations. Reliable experimental measurements at even lower
collision energies are encouraged to confirm the observed isospin effects.
