  We describe the development of, and early experiences with, comprehensive
Digital Phenotyping platform: Health Outcomes through Positive Engagement and
Self-Empowerment (HOPES). HOPES is based on the open-source Beiwe platform but
adds a much wider range of data collection, including the integration of
wearable data sources and further sensor collection from the smartphone.
Requirements were in part derived from a concurrent clinical trial for
schizophrenia. This trial required development of significant capabilities in
HOPES in security, privacy, ease-of-use and scalability, based on a careful
combination of public cloud and on-premises operation. We describe new data
pipelines to clean, process, present and analyze data. This includes a set of
dashboards customized to the needs of the research study operations and for
clinical care. A test use of HOPES is described by analyzing the digital
behaviors of 20 participants during the SARS-CoV-2 pandemic.
