  We predict a scheme for the creation of isotropic three-dimensional droplets
in Rydbeg-dressed Bose gases, which contain both repulsive contact interactions
and attractive van der Waals interactions causing the quantum fluctuation
effect non-negligible. We present detailed beyond mean-field calculations with
Lee-Huang-Yang correction and demonstrate the existence of isotropic droplets
under realistic experimental conditions. Stable droplets possess flat-top
density distribution, and their chemical potentials decrease with the particle
number expansion towarding a critical value. We distinguish droplets from
bright solitons through peak density, width of condensate and quantum depletion
calculations. We summarize a phase diagram of realizing droplets, and
subsequently highlight the stability of droplets by real time evolution as well
as collisions. Our work provides a novel platform for investigating excitation
spectrum and superfluid nature of droplets.
