  In this paper, a network of hypertension-related genes is constructed by
analyzing the correlations of gene expression data among the Dahl
salt-sensitive rat and two consomic rat strains. The numerical calculations
show that this sparse and assortative network has small-world and scale-free
properties. Further, 16 key hub genes (Col4a1, Lcn2, Cdk4, etc.) are determined
by introducing an integrated centrality and have been confirmed by
biological/medical research to play important roles in hypertension.
