  We have undertaken a search for variable stars in the metal-rich globular
cluster NGC 6388 using time-series BV photometry. Twenty-eight new variables
were found in this survey, increasing the total number of variables found near
NGC 6388 to ~57. A significant number of the variables are RR Lyrae (~14), most
of which are probable cluster members. The periods of the fundamental mode RR
Lyrae are shown to be unusually long compared to metal-rich field stars. The
existence of these long period RRab stars suggests that the horizontal branch
of NGC 6388 is unusually bright. This implies that the metallicity-luminosity
relationship for RR Lyrae stars is not universal if the RR Lyrae in NGC 6388
are indeed metal-rich. We consider the alternative possibility that the stars
in NGC 6388 may span a range in [Fe/H]. Four candidate Population II Cepheids
were also found. If they are members of the cluster, NGC 6388 would be the most
metal-rich globular cluster to contain Population II Cepheids. The mean V
magnitude of the RR Lyrae is found to be 16.85+/-0.05 resulting in a distance
of 9.0 to 10.3 kpc, for a range of assumed values of <M_V> for RR Lyrae. We
determine the reddening of the cluster to be E(B-V)=0.40+/-0.03 mag, with
differential reddening across the face of the cluster. We discuss the
difficulty in determining the Oosterhoff classification of NGC 6388 and NGC
6441 due to the unusual nature of their RR Lyrae, and address evolutionary
constraints on a recent suggestion that they are of Oosterhoff type II.
