  Preliminary results are presented for nucleon isovector charges and twist-2
matrix elements which have been obtained employing an improved analysis
strategy to deal with excited-state contamination. The set of CLS $N_f=2+1$
gauge ensembles in this study has been extended compared to our 2018
calculation, including an ensemble at physical quark masses. Besides the
addition of new ensembles, the number of gauge configurations and measurements
has been increased on several of the existing ensembles and the analysis has
been extended to include additional source-sink separations. The ensembles
cover a range of the light quark mass corresponding to $M_\pi\approx
0.130\,\mathrm{MeV} \ldots 350\,\mathrm{MeV}$, four values of the lattice
spacing $a\approx0.05\,\mathrm{fm}\ldots0.09\,\mathrm{fm}$ and a large range of
volumes. Results at the physical point are computed for each observable from a
combined chiral, continuum and finite-volume extrapolation.
