  Pasteur has demonstrated that the chiral components in a racemic mixture can
separate in homochiral crystals. But with a strong chiral discrimination the
chiral components in a concentrated mixture can also phase separate into
homochiral fluid domains, and the isomerization kinetics can then perform a
symmetry breaking into one thermodynamical stable homochiral system.
Glyceraldehyde has a sufficient chiral discrimination to perform such a
symmetry breaking. The requirement of a high concentration of the chiral
reactant(s) in an aqueous solution in order to perform and $\textit{maintain}$
homochirality; the appearance of phosphorylation of almost all carbohydrates in
the central machinery of life; the basic ideas that the biochemistry and the
glycolysis and gluconeogenesis contain the trace of the biochemical evolution,
all point in the direction of that homochirality was obtained just after- or at
a phosphorylation of the very first products of the formose reaction, at high
concentrations of the reactants in phosphate rich compartments in submarine
hydrothermal vents. A racemic solution of D,L-glyceraldehyde-3-phosphate could
be the template for obtaining homochiral D-glyceraldehyde-3-phosphate(aq) as
well as L-amino acids.
