  Type IIB AdS$_6$ solutions with orientifold 7-planes are constructed. The
geometry is a warped product of AdS$_6$ and S$^2$ over a Riemann surface
$\Sigma$ and the O7-planes correspond to a particular type of puncture on
$\Sigma$. The solutions are identified as near-horizon limits of $(p,q)$
5-brane webs with O7-planes. The dual 5d SCFTs have relevant deformations to
linear quiver gauge theories which have $SO(\cdot)$ or $USp(\cdot)$ nodes or
$SU(\cdot)$ nodes with hypermultiplets in symmetric or antisymmetric
representations, in addition to $SU(\cdot)$ nodes with fundamental
hypermultiplets. The S$^5$ free energies are obtained holographically and
matched to field theory computations using supersymmetric localization to
support the proposed dualities.
