  An estimate of the one-loop correction to the power spectrum of the
primordial curvature perturbation is given, assuming it is generated during a
phase of single-field, slow-roll inflation. The loop correction splits into two
parts, which can be calculated separately: a purely quantum-mechanical
contribution which is generated from the interference among quantized field
modes around the time when they cross the horizon, and a classical contribution
which comes from integrating the effect of field modes which have already
passed far beyond the horizon. The loop correction contains logarithms which
may invalidate the use of naive perturbation theory for cosmic microwave
background (CMB) predictions when the scale associated with the CMB is
exponentially different from the scale at which the fundamental theory which
governs inflation is formulated.
