  Preliminary site testing datasets suggest that Dome C in Antarctica is one of
the best sites on Earth for astronomical observations in the 200 to 500 micron
regime, i.e. for far-infrared (FIR) and submillimetre (submm) astronomy. We
present an overview of potential science cases that could be addressed with a
large telescope facility at Dome C. This paper also includes a presentation of
the current knowledge about the site characterics in terms of atmospheric
transmission, stability, sky noise and polar constraints on telescopes. Current
and future site testing campaigns are finally described.
