  We introduce the {Destructive Object Handling} (DOH) problem, which models
aspects of many real-world allocation problems, such as shipping explosive
munitions, scheduling processes in a cluster with fragile nodes, re-using
passwords across multiple websites, and quarantining patients during a disease
outbreak. In these problems, objects must be assigned to handlers, but each
object has a probability of destroying itself and all the other objects
allocated to the same handler. The goal is to maximize the expected value of
the objects handled successfully.
  We show that finding the optimal allocation is
$\mathsf{NP}$-$\mathsf{complete}$, even if all the handlers are identical. We
present an FPTAS when the number of handlers is constant. We note in passing
that the same technique also yields a first FPTAS for the weapons-target
allocation problem \cite{manne_wta} with a constant number of targets. We study
the structure of DOH problems and find that they have a sort of phase
transition -- in some instances it is better to spread risk evenly among the
handlers, in others, one handler should be used as a ``sacrificial lamb''. We
show that the problem is solvable in polynomial time if the destruction
probabilities depend only on the handler to which an object is assigned; if all
the handlers are identical and the objects all have the same value; or if each
handler can be assigned at most one object.
  Finally, we empirically evaluate several heuristics based on a combination of
greedy and genetic algorithms. The proposed heuristics return fairly high
quality solutions to very large problem instances (upto 250 objects and 100
handlers) in tens of seconds.
