  Wolumes is a fast and stand-alone computer program written in standard C that
allows the measure of atom volumes in proteins. Its algorithm is a simple
discretization of the space by means of a grid of points at 0.75 Angstroms from
each other and it uses a set of van der Waals radii optimized for protein
atoms. By comparing the computed values with distributions derived from a
non-redundant subset of the Protein Data Bank, the new methods allows to
identify atoms and residues abnormally large/small. The source code is freely
available, together with some examples.
