  We study an optimal control problem for a non-autonomous SEIRS model with
incidence given by a general function of the infective, the susceptible and the
total population, and with vaccination and treatment as control variables. We
prove existence and uniqueness results for our problem and, for the case of
mass-action incidence, we present some simulation results designed to compare
an autonomous and corresponding periodic model, as well as the controlled
versus uncontrolled models.
