  Using the PIONIER visitor instrument that combines the light of the four
Auxiliary Telescopes of ESO's Very Large Telescope Interferometer, we measure
precisely the diameters of several symbiotic and related stars: HD 352, HD
190658, V1261 Ori, ER Del, FG Ser, and AG Peg. These diameters - in the range
of 0.6 to 2.3 milli-arcseconds - are used to assess the filling factor of the
Roche lobe of the mass-losing giants and provide indications on the nature of
the ongoing mass transfer. We also provide the first spectroscopic orbit of ER
Del, based on CORAVEL and HERMES/Mercator observations. The system is found to
have an eccentric orbit with a period of 5.7 years. In the case of the
symbiotic star FG Ser, we find that the diameter is changing by 13% over the
course of 41 days, while the observations of HD 352 are indicative of an
elongation. Both these stars are found to have a Roche filling factor close to
1, as is most likely the case for HD 190658 as well, while the three other
stars have factors below 0.5-0.6. Our observations reveal the power of
interferometry for the study of interacting binary stars - the main limitation
in our conclusions being the poorly known distances of the objects.
