  A new measurement of the cosmic ray antiproton-to-proton flux ratio between 1
and 100 GeV is presented. The results were obtained with the PAMELA experiment,
which was launched into low-earth orbit on-board the Resurs-DK1 satellite on
June 15th 2006. During 500 days of data collection a total of about 1000
antiprotons have been identified, including 100 above an energy of 20 GeV. The
high-energy results are a ten-fold improvement in statistics with respect to
all previously published data. The data follow the trend expected from
secondary production calculations and significantly constrain contributions
from exotic sources, e.g. dark matter particle annihilations.
