  The cosmic-ray lithium and beryllium ($^{6}$Li, $^{7}$Li, $^{7}$Be, $^{9}$Be,
$^{10}$Be) isotopic composition has been measured with the satellite-borne
experiment PAMELA, which was launched into low-Earth orbit on-board the
Resurs-DK1 satellite on June 15th 2006. The rare lithium and beryllium isotopes
in cosmic rays are believed to originate mainly from the interaction of high
energy carbon, nitrogen and oxygen nuclei with the interstellar medium (ISM),
but also on "tertiary" interactions in the ISM (i.e. produced by further
fragmentation of secondary beryllium and boron). In this paper the isotopic
ratios $^{7}$Li/$^{6}$Li and $^{7}$Be/($^{9}$Be + $^{10}$Be) measured between
150 and 1100 MeV/n using two different detector systems from July 2006 to
September 2014 will be presented.
