  In this talk we discuss SO(10) Yukawa unification and its ramifications for
phenomenology. The initial constraints come from fitting the top, bottom and
tau masses, requiring large $\tan\beta \sim 50$ and particular values for soft
SUSY breaking parameters. We perform a global $\chi^2$ analysis, fitting the
recently observed `Higgs' with mass of order 125 GeV in addition to fermion
masses and mixing angles and several flavor violating observables. We discuss
two distinct GUT scale boundary conditions for soft SUSY breaking masses. In
both cases we have a universal cubic scalar parameter, $A_0$. In the first case
we consider universal gaugino masses, and universal scalar masses, $m_{16}$,
for squarks and sleptons; while in the latter case we have non-universal
gaugino masses and either universal scalar masses, $m_{16}$, for squarks and
sleptons or D-term splitting of scalar masses. We discuss the spectrum of SUSY
particle masses and consequences for the LHC.
