  Recently, the CMS Collaboration performed a search on a new resonance
decaying to $e^\pm\mu^\mp$ in the mass range of 110 GeV to 160 GeV. The search
also hints a possible excess at 146 GeV with a $3.8\sigma~(2.8\sigma)$ of local
(global) significance. Motivated by that, we try to interpret the results in
the context of the type-III two-Higgs-doublet-model. We find that the excess is
only moderately constrained by low-energy lepton-flavor-violation processes, in
particular the $\mu\to e \gamma$ decay. We also compare the CMS bounds across
the entire search region against constraints of $\mu\to e\gamma$ and $\mu\to e$
conversion in nuclei. Our finding indicates that the collider bounds can be
superior to those of low-energy processes for the scalar mass between $110
\text{ GeV}$ and $150 \text{ GeV}$, suggesting the importance of this mass
range for future searches.
