  We theoretically study the effect of uniaxial deformation of ladder-type
cuprate superconductors. Model construction based on first principles
calculation shows that the rung-to-leg ratio of the nearest neighbor hoppings
counterintuitively increases when the lattice is compressed in the longitudinal
(leg) direction. This leads to an enhancement of the superconducting transition
temperature, which intuitively is expected when compressed in the rung
direction. Such a trend is traced back to the on-site hybridization between
Cu$4s$ and Cu$d_{x^2-y^2}$ orbitals, which varies and changes sign upon lattice
deformation.
