  A nonlinear kinetic exclusion model is used to study osmosis and pressure
driven flows through nearly single file pores such as antibiotic channels,
aquaporins, zeolites and nanotubules. Two possible maxima in the steady state
flux as a function of pore-solvent affinity are found. For small driving
forces, the linear macroscopic osmotic and hydraulic permeabilities $P_{os}$
and $L_{p}$, are defined in terms of microscopic kinetic parameters. The
dependences of the flux on activation energies, pore length and radius, and
driving forces are explored and Arrhenius temperature dependences derived.
Reasonable values for the physical parameters used in the analyses yield
transport rates consistent with experimental measurements. Experimental
consequences and interpretations are examined, and a straightforward extension
to osmosis through disordered pores is given.
