  We construct the most general non-extremal deformation of the D-instanton
solution with maximal rotational symmetry. The general non-supersymmetric
solution carries electric charges of the SL(2,R) symmetry, which correspond to
each of the three conjugacy classes of SL(2,R). Our calculations naturally
generalise to arbitrary dimensions and arbitrary dilaton couplings.
  We show that for specific values of the dilaton coupling parameter, the
non-extremal instanton solutions can be viewed as wormholes of non-extremal
Reissner-Nordstr\"om black holes in one higher dimension. We extend this result
by showing that for other values of the dilaton coupling parameter, the
non-extremal instanton solutions can be uplifted to non-extremal non-dilatonic
p-branes in p+1 dimensions higher.
  Finally, we attempt to consider the solutions as instantons of (compactified)
type IIB superstring theory. In particular, we derive an elegant formula for
the instanton action. We conjecture that the non-extremal D-instantons can
contribute to the R^8-terms in the type IIB string effective action.
