  The most general two-Higgs doublet model (2HDM) includes potentially large
sources of flavor changing neutral currents (FCNCs) that must be suppressed in
order to achieve a phenomenologically viable model. The flavor alignment ansatz
postulates that all Yukawa coupling matrices are diagonal when expressed in the
basis of mass-eigenstate fermion fields, in which case tree-level Higgs
mediated FCNCs are eliminated. In this work, we explore models with the flavor
alignment condition imposed at a very high energy scale, which results in the
generation of Higgs-mediated FCNCs via renormalization group running from the
high energy scale to the electroweak scale. Using the current experimental
bounds on flavor changing observables, constraints are derived on the aligned
2HDM parameter space. In the favored parameter region, we analyze the
implications for Higgs boson phenomenology.
