  We describe the impact on PDF extractions of the 'Physical Scheme', a
heavy-quark mass scheme that accounts for the effects of intrinsic heavy-quarks
and provides a way to smoothly transition over the heavy-quark thresholds. The
modifications made to the conventional $\overline{\text{MS}}$ scheme splitting
functions and $\alpha_s$ running will be emphasised, collectively giving rise
to a new Physical Scheme PDF evolution. We also present the analytic formulae
for the DIS coefficient functions at NLO in the Physical Scheme and show
results for the $F_2$ charm DIS structure function. Motivated by the upcoming
statistics from the High-Luminosity LHC, embodying the next phase of the
precision physics era at the LHC, as well as in time from the Electron-Ion
collider, we end by highlighting the need to quantify the effect of these
corrections on PDF extractions over a wide range of momentum fractions $x$ and
scales $Q^2$ and propose the use of $\texttt{xFitter}$ for doing so.
