  SKCM is the most dangerous one of skin cancer, its high degree of malignant,
is the leading cause of skin cancer. And the level of radiation treatment and
chemical treatment is minimal, so the mortality is high. Because of its complex
molecular and cellular heterogeneity, the existing prediction model of skin
cancer risk is not ideal. In this study, we developed an immune-related lncRNAs
model to predict the prognosis of patients with SKCM. Screening for
SKCM-related differential expression of lncRNA from TCGA. Identified
immune-related lncRNAs and lncRNA-related mRNA based on the co-expression
method. Through univariate and multivariate analysis, an immune-related lncRNA
model is established to analyze the prognosis of SKCM patients. A 4-lncRNA skin
cancer prediction model was constructed, including MIR155HG, AL137003.2,
AC011374.2, and AC009495.2. According to the model, SKCM samples were divided
into a high-risk group and low-risk group, and predict the survival of the two
groups in 30 years. The area under the ROC curve is 0.749, which shows that the
model has excellent performance. We constructed a 4-lncRNA model to predict the
prognosis of patients with SKCM, indicating that these lncRNAs may play a
unique role in the carcinogenesis of SKCM.
