  This paper presents the Derivatives Combination Predictor (DCP), a novel
model fusion algorithm for making long-term glucose predictions for diabetic
people. First, using the history of glucose predictions made by several models,
the future glucose variation at a given horizon is predicted. Then, by
accumulating the past predicted variations starting from a known glucose value,
the fused glucose prediction is computed. A new loss function is introduced to
make the DCP model learn to react faster to changes in glucose variations.
  The algorithm has been tested on 10 \textit{in-silico} type-1 diabetic
children from the T1DMS software. Three initial predictors have been used: a
Gaussian process regressor, a feed-forward neural network and an extreme
learning machine model. The DCP and two other fusion algorithms have been
evaluated at a prediction horizon of 120 minutes with the root-mean-squared
error of the prediction, the root-mean-squared error of the predicted
variation, and the continuous glucose-error grid analysis.
  By making a successful trade-off between prediction accuracy and
predicted-variation accuracy, the DCP, alongside with its specifically designed
loss function, improves the clinical acceptability of the predictions, and
therefore the safety of the model for diabetic people.
