  We report evidence for direct CP violation in the decay B0 -> K+-pi-+ with
253/fb of data collected with the Belle detector at the KEKB e+e- collider.
Using 275 million B B_bar pairs we observe a B -> K+-pi-+ signal with 2140+-53
events. The measured CP violating asymmetry is Acp(K+-pi-+) = -0.101+-0.025
(stat)+-0.005 (syst), corresponding to a significance of 3.9 sigma including
systematics. We also search for CP violation in the decays B+- -> K+-pi0 and
B+- -> pi+-pi0. The measured CP violating asymmetries are Acp(K+-pi0) =
0.04+-0.05(stat)+-0.02(syst) and Acp(pi+-pi0) = -0.02+-0.10(stat)+-0.01(syst),
corresponding to the intervals -0.05 < Acp(K+-pi0) < 0.13 and
-0.18<Acp(pi+-pi0)<0.14 at 90% confidence level.
