  Inclusive bottom hadron decays are analyzed based on the heavy quark
effective field theory (HQEFT). Special attentions in this paper are paid to
the b\to u transitions and nonspectator effects. As a consequence, the CKM
quark mixing matrix elements |V_ub| and |V_cb| are reliably extracted from the
inclusive semileptonic decays B\to X_u e \nu and B\to X_c e \nu. Various
observables, such as the semileptonic branch ratio B_SL, the lifetime
differences among B^-, B^0, B_s and \Lambda_b hadrons, the charm counting n_c,
are predicted and found to be consistent with the present experimental data.
