  Extending the single photon transmission distance is a basic requirement for
the implementation of quantum communication on a global scale. In this work we
report the single photon exchange from a medium Earth orbit satellite (MEO) at
more than 7000 km of slanted distance to the ground station at the Matera Laser
Ranging Observatory. The single photon transmitter was realized by exploiting
the corner cube retro-reflectors mounted on the LAGEOS-2 satellite. Long
duration of data collection is possible with such altitude, up to 43 minutes in
a single passage. The mean number of photons per pulse ({\mu}sat) has been
limited to 1 for 200 seconds, resulting in an average detection rate of 3.0 cps
and a signal to noise ratio of 1.5. The feasibility of single photon exchange
from MEO satellites paves the way to tests of Quantum Mechanics in moving
frames and to global Quantum Information.
