  RKappa is a framework for the development, simulation and analysis of
rule-base models within the mature statistically empowered R environment. It is
designed for model editing, parameter identification, simulation, sensitivity
analysis and visualisation. The framework is optimised for high-performance
computing platforms and facilitates analysis of large-scale systems biology
models where knowledge of exact mechanisms is limited and parameter values are
uncertain. The RKappa software is an open source (GLP3 license) package for R,
which is freely available online ( https://github.com/lptolik/R4Kappa ).
