  Specific lipid environments are necessary for the establishment of protein
signalling platforms in membranes, yet their origin has been highly debated. We
present a continuum, exactly solvable model of protein induced local demixing
of lipid membranes. The coupling between a local composition and a local
thickness of the membrane induces lipid domains around inclusions with
hydrophobic mismatch, even for temperatures above the miscibility critical
point of the membrane. The model qualitatively explains the experimentally
observed formation of lipid domains induced by anchoring of reconstituted actin
in flat supported lipid bilayers.
