  The fields of study encompassed by cyber science and engineering are broad
and poorly defined at this time. As national governments and research
communities increase their recognition of the importance, urgency and technical
richness of these disciplines, a question of priorities arises: what specific
sub-areas of research should be the foci of attention and funding? In this
paper we point to an approach to answering this question. We explore results of
a recent workshop that postulated possible game-changers or disruptive changes
that might occur in cyber security within the next 15 years. We suggest that
such game-changers may be useful in focusing attention of research communities
on high-priority topics. Indeed, if a drastic, important change is likely to
occur, should we not focus our research efforts on the nature and ramifications
of the phenomena pertaining to that change? We illustrate each of the
game-changers examples of related current research, and then offer
recommendations for advancement of cyber science and engineering with respect
to each of the six game-changers.
