  In this paper we investigate the effect of anisotropic growth on Glagov
remodeling in different cases: pure radial, pure circumferential, pure axial
and general anisotropic growth. We use the theory of morphoelasticity on an
axisymmetric arterial domain. For each case we explore their specific effect on
the Glagov curves and stress and provide the changes in collagen fibers angles
in the intima, media and adventitia. In addition, we compare the strain energy
produced by growth in radial, circumferential and axial direction and deduce
that anisotropic growth generally leads to lower strain energy than isotropic
growth. Therefore, we explore an anisotropic growth regime and use the
resulting model to simulate vessel remodeling. We compare the Glagov curves,
stress, energies and fiber angles in the anisotropic case with those of the
isotropic case. Our results show that the anisotropic growth produces a
remodeling curve more consistent with Glagov's experimental data with gentler
outward remodeling and more realistic stress profiles.
