  We present a study of the photometric variability of spectroscopically
confirmed supergiants in NGC 300, comprising 28 epochs extending over a period
of five months. We find 15 clearly photometrically variable blue supergiants in
a sample of nearly 70 such stars, showing maximum light amplitudes ranging from
0.08 to 0.23 magnitudes in the V band, and one variable red supergiant. We show
their light curves, and determine semi-periods for two A2 Ia stars. Assuming
that the observed changes correspond to similar variations in the bolometric
luminosity, we test for the influence of this variability on the Flux-weighted
Gravity--Luminosity Relationship and find a negligible effect, showing that the
calibration of this relationship, which has the potential to measure
extragalactic distances at the Cepheid accuracy level, is not affected by the
stellar photometric variability in any significant way.
