  Finite element analysis (FEA) can be used to evaluate applied interface
pressures and internal tissue strains for computational prosthetic socket
design. This type of framework requires realistic patient-specific limb
geometry and constitutive properties. In recent studies, indentations and
inverse FEA with MRI-derived 3D patient geometries were used for constitutive
parameter identification. However, long computational times and use of
specialized equipment presents challenges for clinical deployment. In this
study, we present a novel approach for constitutive parameter identification
using a combination of FEA, ultrasound indentation, and shear wave
elastography. Local shear modulus measurement using elastography during an
ultrasound indentation experiment has particular significance for biomechanical
modeling of the residual limb since there are known regional dependencies of
soft tissue properties such as varying levels of scarring and atrophy. Beyond
prosthesis design, this work has broader implications to the fields of muscle
health and monitoring of disease progression.
