  In this work, we examine in detail the difference between constraining the
electric charge fraction and isospin fraction when calculating the
deconfinement phase transition in the presence of net strangeness. We present
relations among charge and isospin fractions and the corresponding chemical
potentials and draw 3-dimensional QCD phase diagrams for matter out of weak
equilibrium. Finally, we briefly discuss how our results can be applied to
comparisons of matter created in heavy ion collisions and binary neutron star
mergers.
