  It is shown that the 750 GeV diphoton excess can be explained in extensions
of Two-Higgs-Doublet Models that do not involve large multiplicities of new
electromagnetically charged states. The key observation is that at moderate and
large $\tan\beta$ the total decay width of the 750 GeV Higgs is strongly
reduced as compared to the Standard Model. This allows for much more economical
choices of new states that enhance the diphoton signal to fit the data. In
particular, it is shown that one family of vector-like quarks and leptons with
SM charges is enough to explain the 750 GeV diphoton excess. Moreover, such
charge assignment can keep the 125 GeV Higgs signal rates exactly at the SM
values. The scenario can interpret the diphoton excess provided that the total
decay width of a hypothetical resonance that would be measured at the LHC turns
out to not exceed few GeV.
