  A computer-aided detection (CADe) system for microcalcification cluster
identification in mammograms has been developed in the framework of the
EU-founded MammoGrid project. The CADe software is mainly based on wavelet
transforms and artificial neural networks. It is able to identify
microcalcifications in different kinds of mammograms (i.e. acquired with
different machines and settings, digitized with different pitch and bit depth
or direct digital ones). The CADe can be remotely run from GRID-connected
acquisition and annotation stations, supporting clinicians from geographically
distant locations in the interpretation of mammographic data. We report the
FROC analyses of the CADe system performances on three different dataset of
mammograms, i.e. images of the CALMA INFN-founded database collected in the
Italian National screening program, the MIAS database and the so-far collected
MammoGrid images. The sensitivity values of 88% at a rate of 2.15 false
positive findings per image (FP/im), 88% with 2.18 FP/im and 87% with 5.7 FP/im
have been obtained on the CALMA, MIAS and MammoGrid database respectively.
