  This paper describes a method for identification of the informative variables
in the information system with discrete decision variables. It is targeted
specifically towards discovery of the variables that are non-informative when
considered alone, but are informative when the synergistic interactions between
multiple variables are considered. To this end, the mutual entropy of all
possible k-tuples of variables with decision variable is computed. Then, for
each variable the maximal information gain due to interactions with other
variables is obtained. For non-informative variables this quantity conforms to
the well known statistical distributions. This allows for discerning truly
informative variables from non-informative ones. For demonstration of the
approach, the method is applied to several synthetic datasets that involve
complex multidimensional interactions between variables. It is capable of
identifying most important informative variables, even in the case when the
dimensionality of the analysis is smaller than the true dimensionality of the
problem. What is more, the high sensitivity of the algorithm allows for
detection of the influence of nuisance variables on the response variable.
