  KLYPVE-EUSO (K-EUSO) is a planned orbital detector of ultra-high-energy
cosmic rays (UHECRs), which is to be deployed on board the International Space
Station. K-EUSO is expected to have a uniform exposure over the celestial
sphere and register from 120 to 500 UHECRs at energies above 57 EeV in a 2-year
mission. We employed the TransportCR and CRPropa 3 packages to estimate
prospects of detecting a large-scale anisotropy of ultra-high-energy cosmic
rays from a nearby source with K-EUSO. Nearby active galactic nuclei Centaurus
A, M82, NGC 253, M87 and Fornax A were considered as possible sources of
UHECRs. A minimal model for extragalactic cosmic rays and neutrinos by
Kachelriess, Kalashev, Ostapchenko and Semikoz (2017) was chosen for
definiteness. We demonstrate that an observation of $\gtrsim300$ events will
allow detecting a large-scale anisotropy with a high confidence level providing
the fraction of from-source events is $\simeq$10-15%, depending on a particular
source. The threshold fraction decreases with an increasing sample size. We
also discuss if an overdensity originating from a nearby source can be observed
at around the ankle in case a similar anisotropy is found beyond 57 EeV. The
results are generic and hold for other future experiments with a uniform
exposure of the celestial sphere.
