  Reaction constants in traditional Michaelis-Menten type enzyme kinetics are
most often determined through a linear Lineweaver-Burk plot. While such a
graphical plot is sometimes good to achieve the end, it is always better to go
for a few numerical tests that can assess the quality of the data set being
used and hence offer more reliable measures of the quantities sought,
furnishing along with appropriate error estimates. In this context, we
specifically highlight how cases may appear with negative reaction constants
and explore the origin of such bizarre findings.
