  Currently there are many clinical trials using paper case report forms as the
primary data collection tool. Cloud Computing platforms provide big potential
for increasing efficiency through a web-based data collection interface,
especially for large-scale multi-center trials. Traditionally, clinical and
biological data for multi-center trials are stored in one dedicated,
centralized database system running at a data coordinating center (DCC). This
paper presents C-PASS-PC, a cloud-driven prototype of multi-center proactive
surveillance system for prostate cancer. The prototype is developed in PHP,
JQuery and CSS with an Oracle backend in a local Web server and database server
and deployed on Google App Engine (GAE) and Google Cloud SQL-MySQL. The
deploying process is fast and easy to follow. The C-PASS-PC prototype can be
accessed through an SSL-enabled web browser. Our approach proves the concept
that cloud computing platforms such as GAE is a suitable and flexible solution
in the near future for multi-center clinical trials.
