  We present new multi-wavelength observations of the dwarf Seyfert 1 galaxy
POX 52 in order to investigate the properties of the host galaxy and the active
nucleus, and to examine the mass of its black hole, previously estimated to be
~ 10^5 M_sun. Hubble Space Telescope ACS/HRC images show that the host galaxy
has a dwarf elliptical morphology (M_I = -18.4 mag, Sersic index n = 4.3) with
no detected disk component or spiral structure, confirming previous results
from ground-based imaging. X-ray observations from both Chandra and XMM show
strong (factor of 2) variability over timescales as short as 500 s, as well as
a dramatic decrease in the absorbing column density over a 9 month period. We
attribute this change to a partial covering absorber, with a 94% covering
fraction and N_H = 58^{+8.4}_{-9.2} * 10^21 cm^-2, that moved out of the line
of sight in between the XMM and Chandra observations. Combining these data with
observations from the VLA, Spitzer, and archival data from 2MASS and GALEX, we
examine the spectral energy distribution (SED) of the active nucleus. Its shape
is broadly similar to typical radio-quiet quasar SEDs, despite the very low
bolometric luminosity of L_bol = 1.3 * 10^43 ergs/s. Finally, we compare black
hole mass estimators including methods based on X-ray variability, and optical
scaling relations using the broad H-beta line width and AGN continuum
luminosity, finding a range of black hole mass from all methods to be M_bh =
(2.2-4.2) * 10^5 M_sun, with an Eddington ratio of L_bol/L_edd = 0.2-0.5.
