  We compute the four-point amplitude with external adjoint particles in
$\mathcal{N}=2$ SCQCD at two loops using $\mathcal{N}=1$ superspace Feynman
diagrams, extending the results of arXiv:1406.7283. We consider the
diagrammatic difference with the corresponding process of $\mathcal{N}=4$ SYM
finding a non vanishing result, which is a non trivial function of the
kinematic variables. This demonstrates that in $\mathcal{N}=2$ SCQCD, even in
the sector with external particles in the vector multiplet, the
amplitude/Wilson loop duality is inevitably broken at two loops.
