  This paper proposes a methodology to extract a low-dimensional
integrate-and-fire model from an arbitrarily detailed single-compartment
biophysical model. The method aims at relating the modulation of maximal
conductance parameters in the biophysical model to the modulation of parameters
in the proposed integrate-and-fire model. The approach is illustrated on two
well-documented examples of cellular neuromodulation: the transition between
Type I and Type II excitability and the transition between spiking and
bursting.
