  This report investigates design enhancements of Fiber Optic Surface Plasmon
Resonance (FO-SPR) biosensors with Gold and Silver metallic films. The effect
of adding a Graphene coating on the sensitivity and detection accuracy of
FO-SPR biosensors is studied. We also compare the results for the addition of
five layers of Graphene on both Gold-based and Silver-based FO-SPR biosensors
in order to determine the optimum sensor design. Our results indicate that the
sensitivity of the biosensor increases when a Graphene coating is added, while
the detection accuracy decreases. Results also demonstrate that the sensitivity
due to adding Graphene sheets increases more for Silver-based biosensor when
compared to Gold-based biosensors.
