  Phantom eye devices are designed to mimic the optical properties of the human
eye; however, the retinal structures are typically emulated with synthetic
tissues. Thus, it is currently impossible to exploit phantom eye devices for
fluorescence microscopy experiments on cultures, or ex-vivo tissues, although
these ophthalmic measurements would be of importance for many applications such
as the testing of retinal biomarkers. Here we report and describe the
development of a phantom eye designed to host biological samples, such as
retinal cultures differentiated from human induced pluripotent stem cells. We
characterized the imaging performance of the humanized phantom eye on standard
biomarkers such as Alexa Fluor 532 and Alexa fluor 594.
