  We argue that in large classes of string compactifications with a MSSM-like
structure substantial flavor violating SUSY-breaking soft terms are generically
induced. We specify to the case of flavor dependent soft-terms in type
IIB/F-theory SU(5) unified models, although our results can be easily extended
to other settings. The Standard Model (SM) degrees of freedom reside in a local
system of 7-branes wrapping a 4-fold S in the extra dimensions. It is known
that in the presence of closed string 3-form fluxes SUSY-breaking terms are
typically generated. We explore the generation dependence of these soft terms
and find that non-universalities arise whenever the flux varies over the 4-fold
S. These non-universalities are parametrically suppressed by
(M_{GUT}/M_{Pl})^{1/3}. They also arise in the case of varying open string
fluxes, in this case parametrically suppressed by \alpha_{GUT}^{1/2}. For a
standard unification scheme with M_{GUT} = 10^{16} GeV and \alpha_{\rm GUT} =
1/24 these suppressions are very mild. Although limits from the kaon mass
difference \Delta m_K are easily obeyed for squark masses above the present LHC
limits, constraints from the CP-violation parameter \epsilon_K imply squark
masses in the multi-TeV region. The constraints from BR(\mu \rightarrow
e\gamma) turn out to be the strongest ones, with slepton masses of order ~10
TeV or heavier required to obey the experimental limits. These sfermion masses
are consistent with the observed large value m_H ~ 126 GeV of the Higgs mass.
We discuss under what conditions such strong limits may be relaxed allowing for
SUSY particle production at LHC.
