  Protein-protein interactions (PPIs) perform important roles on biological
functions. Researches of mutants on protein interactions can further understand
PPIs. In the past, many researchers have developed databases that stored
mutants on protein interactions, which are old and not updated till now. To
address the issue, we developed a kinetic and thermodynamic database of mutant
protein interactions (dbMPIKT) that can be freely accessible at our website.
This database contains 5291 mutants that integrated data from previous
databases and data from literatures for nearly three years. Furthermore, the
data were analyzed, involving mutation number, mutation type, protein pair
source and network map construction. On the whole, the database provides new
data to further improve the study on PPIs. Website:
http://210.45.212.128/lqy/index.php
