  Complex computer simulators are increasingly used across fields of science as
generative models tying parameters of an underlying theory to experimental
observations. Inference in this setup is often difficult, as simulators rarely
admit a tractable density or likelihood function. We introduce Adversarial
Variational Optimization (AVO), a likelihood-free inference algorithm for
fitting a non-differentiable generative model incorporating ideas from
generative adversarial networks, variational optimization and empirical Bayes.
We adapt the training procedure of generative adversarial networks by replacing
the differentiable generative network with a domain-specific simulator. We
solve the resulting non-differentiable minimax problem by minimizing
variational upper bounds of the two adversarial objectives. Effectively, the
procedure results in learning a proposal distribution over simulator
parameters, such that the JS divergence between the marginal distribution of
the synthetic data and the empirical distribution of observed data is
minimized. We evaluate and compare the method with simulators producing both
discrete and continuous data.
