  In this communication, we propose a model to study the non-equilibrium
process by which actin stress fibers develop force in contractile cells. The
emphasis here is on the non-equilibrium thermodynamics, which is necessary to
address the mechanics as well as the chemistry of dynamic cell contractility.
In this setting we are able to develop a framework that relates (a) the
dynamics of force generation within the cell and (b) the cell response to
external stimuli to the chemical processes occurring within the cell, as well
as to the mechanics of linkage between the stress fibers, focal adhesions and
extra-cellular matrix.
