  Hemodynamic parameters have been estimated assuming a Newtonian constant
viscosity, even when blood exhibits shear-thinning behavior. This article
investigates the influence of blood rheology and hematocrit percentage on
estimating Wall Shear Stress (WSS) and Energy Loss ($E_L$) at different time
instants of the cardiac cycle, as well as the Oscillatory Shear Index (OSI). We
specifically focus on a hematocrit-dependent power-law non-Newtonian model,
considering a wide range of hematocrit values. The rheological parameters are
obtained from experimentally fitted data reported previously. This study
contributes to understanding the impact of blood rheology on hemodynamic
parameter estimations using both in-silico and in-vivo aortic 4D Flow magnetic
resonance images. Across all cases, we systematically compared WSS, $E_L$, and
OSI parameters using Newtonian and power-law models, highlighting the crucial
role of blood rheology in accurately assessing cardiovascular diseases.
