  Ultraviolet absorption from interstellar 12CO and 13CO was detected toward
rho Oph A and chi Oph. The measurements were obtained at medium resolution with
the Goddard High Resolution Spectrograph on the Hubble Space Telescope. Column
density ratios, N(12CO)/N(13CO), of 125 \pm 23 and 117 \pm 35 were derived for
the sight lines toward rho Oph A and chi Oph, respectively. A value of 1100 \pm
600 for the ratio N(12C16O)/N(12C18O) toward rho Oph A was also obtained.
Absorption from vibrationally excited H_2 (v" = 3) was clearly seen toward this
star as well.
  The ratios are larger than the isotopic ratios for carbon and oxygen
appropriate for ambient interstellar material. Since for both carbon and oxygen
the more abundant isotopomer is enhanced, selective isotopic photodissociation
plays the key role in the fractionation process for these directions. The
enhancement arises because the more abundant isotopomer has lines that are more
optically thick, resulting in more self shielding from dissociating radiation.
A simple argument involving the amount of self shielding [from N(12CO)] and the
strength of the ultraviolet radiation field premeating the gas (from the amount
of vibrationally excited H_2) shows that selective isotopic photodissociation
controls the fractionation seen in these two sight lines, as well as the sight
line to zeta Oph.
