  We have developed a coherent Raman imaging platform using broadband coherent
anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination
of speed, sensitivity, and spectral breadth. The system utilizes a unique
configuration of laser sources that probes the Raman spectrum over 3,000
cm$^{-1}$ and generates an especially strong response in the typically weak
Raman "fingerprint" region through heterodyne amplification of the anti-Stokes
photons with a large nonresonant background (NRB) while maintaining high
spectral resolution of $<$ 13 cm$^{-1}$. For histology and pathology, this
system shows promise in highlighting major tissue components in a
non-destructive, label-free manner. We demonstrate high-speed chemical imaging
in two- and three-dimensional views of healthy murine liver and pancreas
tissues and interfaces between xenograft brain tumors and the surrounding
healthy brain matter.
