  We investigate the science goals achievable with the upcoming generation of
ground-based Cosmic Microwave Background polarization experiments and calculate
the optimal sky coverage for such an experiment including the effects of
foregrounds. We find that with current technology an E-mode measurement will be
sample-limited, while a B-mode measurement will be detector-noise-limited. We
conclude that a 300 sq deg survey is an optimal compromise for a two-year
experiment to measure both E and B-modes, and that ground-based polarization
experiments can make an important contribution to B-mode surveys. Focusing on
one particular experiment, QUaD, a proposed bolometric polarimeter operating
from the South Pole, we find that a ground-based experiment can make a high
significance measurement of the acoustic peaks in the E-mode spectrum, and will
be able to detect the gravitational lensing signal in the B-mode spectrum. Such
an experiment could also directly detect the gravitational wave component of
the B-mode spectrum if the amplitude of the signal is close to current upper
limits. We also investigate how a ground-based experiment can improve
constraints on the cosmological parameters. We estimate that by combining two
years of QUaD data with the four-year WMAP data, an optimized ground-based
polarization experiment can improve constraints on cosmological parameters by a
factor of two. If the foreground contamination can be reduced, the measurement
of the tensor-to-scalar ratio can be improved by up to a factor of six over
that obtainable from WMAP alone.
