  Accurate detection of arterial input function is a crucial step in obtaining
perfusion hemodynamic parameters using dynamic susceptibility contrast-enhanced
magnetic resonance imaging. It is required as input for perfusion
quantification and has a great impact on the result of the deconvolution
operation. To improve the reproducibility and reliability of arterial input
function detection, several semi- or fully automatic methods have been
proposed. This study provides an overview of the current state of the field of
arterial input function detection. Methods most commonly used for semi- and
fully automatic arterial input function detection are reviewed, and their
advantages and disadvantages are listed.
