  We introduce a novel method to design and implement a tunable dynamical
tissue phantom for laser speckle-based in-vivo blood flow imaging. This
approach relies on Stochastic Differential Equations (SDE) to control a
piezoelectric actuator which, upon illuminated with a laser source, generates
speckles of pre-defined probability density function and auto-correlation. The
validation experiments show that the phantom can generate dynamic speckles that
closely replicate both surfaces as well as deep tissue blood flow for a
reasonably wide range and accuracy.
