  Obstructive sleep apnea (OSA) is a complex disease with complex etiology,
which requires multidisciplinary cooperation in diagnosis and treatment.
Mandibular retrognathia is strongly associated with OSA. Orthodontists can
either correct the mandibular retrognathia of pediatric OSA via various kinds
of orthodontic appliances, following adenoidectomy and tonsillectomy, or
enlarge upper airway by mandibular advancement device (MAD) through
repositioning the mandible and tongue of adult OSA patients. This mini review
was to investigate the therapy of MAD to adult OSA as well as orthodontic
treatment to pediatric OSA.
