  Optical coherence tomography (OCT) is commonly used to analyze retinal layers
for assessment of ocular diseases. In this paper, we propose a method for
retinal layer segmentation and quantification of uncertainty based on Bayesian
deep learning. Our method not only performs end-to-end segmentation of retinal
layers, but also gives the pixel wise uncertainty measure of the segmentation
output. The generated uncertainty map can be used to identify erroneously
segmented image regions which is useful in downstream analysis. We have
validated our method on a dataset of 1487 images obtained from 15 subjects (OCT
volumes) and compared it against the state-of-the-art segmentation algorithms
that does not take uncertainty into account. The proposed uncertainty based
segmentation method results in comparable or improved performance, and most
importantly is more robust against noise.
