  Several lines of evidence point to a relationship between gamma-ray bursts
(GRBs) and the high mass stars that explode as supernovae. Arguments that GRB
sources accelerate cosmic rays (CRs) are summarized. High-energy neutrino
detection from individual GRBs would mean that they are hadronically dominated,
that is, that the amount of energy deposited in the form of nonthermal hadrons
in GRB blast waves greatly exceeds the radiated energy inferred from their
photon emission spectra. Such a detection would make GRBs the favored candidate
sources of ultra-high energy and super-GZK CRs. Cascade radiation induced by
high-energy hadrons could be detected from GRBs with gamma-ray telescopes.
