  In this paper, we couple together the dust evolution code two-pop-py with the
thermochemical disk modelling code ProDiMo. We create a series of
thermochemical disk models that simulate the evolution of dust over time from
0.018 Myr to 10 Myr, including the radial drift, growth, and settling of dust
grains. We examine the effects of this dust evolution on the mid-infrared gas
emission, focussing on the mid-infrared spectral lines of C2H2, CO2, HCN, NH3,
OH, and H2O that are readily observable with Spitzer and the upcoming E-ELT and
JWST.
  The addition of dust evolution acts to increase line fluxes by reducing the
population of small dust grains. We find that the spectral lines of all species
except C2H2 respond strongly to dust evolution, with line fluxes increasing by
more than an order of magnitude across the model series as the density of small
dust grains decreases over time. The C2H2 line fluxes are extremely low due to
a lack of abundance in the infrared line-emitting regions, despite C2H2 being
commonly detected with Spitzer, suggesting that warm chemistry in the inner
disk may need further investigation. Finally, we find that the CO2 flux
densities increase more rapidly than the other species as the dust disk
evolves. This suggests that the flux ratios of CO2 to other species may be
lower in disks with less-evolved dust populations.
