  We discuss pore dynamics in osmotically stressed vesicles. A set of equations
which govern the liposomal size, internal solute concentration, and pore
diameter is solved numerically. We find that dependent on the internal solute
concentration and vesicle size, liposomes can stay pore-free, nucleate a short
lived pore, or nucleate a long-lived pore. The phase diagram of pore stability
is constructed, and the different scaling regimes are deduced analytically.
