  Let $R$ be a ring with $char(R)\neq2$ whose unit group are denoted by
$\mathcal{U}(R)$, $G$ a group with involution $*$, and
$\sigma:G\rightarrow\mathcal{U}(R)$ a nontrivial group homomorphism, with $ker\
\sigma=N$, satisfying $xx^*\in N$ for all $x\in G$. Let $RG$ be the group ring
of $G$ over $R$ and define the involution $\sigma*$ in $RG$ by $\left(
\sum_{x\in G}\alpha_xx\right)^{\sigma*}=\sum_{x\in G}\sigma(x)\alpha_xx^*$. In
this paper, we will classify the group rings $RG$ such that $\mathcal{S}$ is
anticommutative, where $\mathcal{S}$ is the largest subset of $(RG)^+=\left\{
\alpha\in RG: \alpha^{\sigma *}=\alpha\right\}$ that can satisfy
anticommutativity under $char(R)\neq2$.
