  This review mainly focuses on the relation between antioxidants with cancer
therapy. Antioxidants have been reported to play an essential role to reduce
free radical species. Free radicals commonly cause oxidative damage which is a
common factor in the aging process, and also the vital factor of formation, and
development of major disease specially cancer. Although, since last many
decades several antioxidants belong to natural and synthetic origin have been
tested in clinical trials against oxidative stress, however these clinical
trials end up with undesirable effects. This review also complied with the most
recent findings of oxidative stress, highlighting of free racial production,
and its related oxidative damage at cellular and molecular level, with the new
and existing natural and synthetic classes of free radical scavenger and their
related clinical trials.
