  Gene expression data, or transcription data, are surrogates for actual
protein concentrations in the cells. In addition protein-protein interactions
are static diagrams of all the protein-protein interactions in the cell. These
interactions may consist of covalent bonding or maybe just secondary bonding
such as hydrogen bonding. Given these two surrogate data types we show a
technique to compute the Gibbs free energy of a cell. We apply this to yeast
cell cycle and to cancer.
