  The solid content of circumstellar disks is inherited from the interstellar
medium: dust particles of at most a micrometer in size. Protoplanetary disks
are the environment where these dust grains need to grow at least 13 orders of
magnitude in size. Our understanding of this growth process is far from
complete, with different physics seemingly posing obstacles to this growth at
various stages. Yet, the ubiquity of planets in our galaxy suggests that planet
formation is a robust mechanism. This chapter focuses on the earliest stages of
planet formation, the growth of small dust grains towards the gravitationally
bound "planetesimals", the building blocks of planets. We will introduce some
of the key physics involved in the growth processes and discuss how they are
expected to shape the global behavior of the solid content of disks. We will
consider possible pathways towards the formation of larger bodies and conclude
by reviewing some of the recent observational advances in the field.
