  Quantum key distribution is on the verge of real world applications, where
perfectly secure information can be distributed among multiple parties. Several
quantum cryptographic protocols have been theoretically proposed and
independently realized in different experimental conditions. Here, we develop
an experimental platform based on high-dimensional orbital angular momentum
states of single photons that enables implementation of multiple quantum key
distribution protocols with a single experimental apparatus. Our versatile
approach allows us to experimentally survey different classes of quantum key
distribution techniques, such as the 1984 Bennett \& Brassard (BB84),
tomographic protocols including the six-state and the Singapore protocol, and
to investigate, for the first time, a recently introduced differential phase
shift (Chau15) protocol using twisted photons. This enables us to
experimentally compare the performance of these techniques and discuss their
benefits and deficiencies in terms of noise tolerance in different dimensions.
