  We calculate various quantities that characterize the dissimilarity of
reduced density matrices for a short interval of length $\ell$ in a
two-dimensional (2D) large central charge conformal field theory (CFT). These
quantities include the R\'enyi entropy, entanglement entropy, relative entropy,
Jensen-Shannon divergence, as well as the Schatten 2-norm and 4-norm. We adopt
the method of operator product expansion of twist operators, and calculate the
short interval expansion of these quantities up to order of $\ell^9$ for the
contributions from the vacuum conformal family. The formal forms of these
dissimilarity measures and the derived Fisher information metric from
contributions of general operators are also given. As an application of the
results, we use these dissimilarity measures to compare the excited and thermal
states, and examine the eigenstate thermalization hypothesis (ETH) by showing
how they behave in high temperature limit. This would help to understand how
ETH in 2D CFT can be defined more precisely. We discuss the possibility that
all the dissimilarity measures considered here vanish when comparing the
reduced density matrices of an excited state and a generalized Gibbs ensemble
thermal state. We also discuss ETH for a microcanonical ensemble thermal state
in a 2D large central charge CFT, and find that it is approximately satisfied
for a small subsystem and violated for a large subsystem.
