  We construct a flavor model in an anti-SU(5) GUT with a tetrahedral symmetry
$A_4$. We choose a basis where $Q_{text{em}}=-\frac13$ quarks and charged
leptons are already mass eigenstates. This choice is possible from the $A_4$
symmetry. Then, matter representation $\overline{10}_{-1}^{\rm\, matter}$
contains both a quark doublet and a heavy neutrino $N$, which enables us to use
the $A_4$ symmetry to both $Q_{text{em}}=+\frac23$ quark masses and neutrino
masses (through the see-saw via $N$). This is made possible because the
anti-SU(5) breaking is achieved by the Higgs fields transforming as
anti-symmetric representations of SU(5), $\overline{10}_{-1}^H\oplus
10_{+1}^H$, reducing the rank-5 anti-SU(5) group down to the rank-4 standard
model group \smg. For possible mass matrices, the $A_4$ symmetry predictions on
mass matrices at field theory level are derived. Finally, an illustration from
string compactification is presented.
