  Twisting two layers into a magic angle (MA) of ~1.1{\deg} is found essential
to create low energy flat bands and the resulting correlated insulating,
superconducting, and magnetic phases in twisted bilayer graphene (TBG). While
most of previous works focus on revealing these emergent states in MA-TBG, a
study of the twist angle dependence, which helps to map an evolution of these
phases, is yet less explored. Here, we report a magneto-transport study on one
non-magic angle TBG device, whose twist angle {\theta} changes from 1.25{\deg}
at one end to 1.43{\deg} at the other. For {\theta}=1.25{\deg}, we observe an
emergence of topological insulating states at hole side with a sequence of
Chern number |C|=4-|v|, where v is the number of electrons (holes) in moir\'e
unite cell. When {\theta}>1.25{\deg}, the Chern insulator from flat band
disappears and evolves into fractal Hofstadter butterfly quantum Hall insulator
where magnetic flux in one moir\'e unite cell matters. Our observations will
stimulate further theoretical and experimental investigations on the
relationship between electron interactions and non-trivial band topology.
