  We define two different systems of mathematical physics: the second-order
differential system (SODS) and the first-order differential system (FODS). The
Newton's second law of motion and the nonlinear Schr\"{o}dinger equation (NLSE)
are the exemplary SODS and FODS, respectively. We obtain a new kind of
canonical equations of Hamilton (CEH), which are of some kind of symmetry in
form and are formally different with the conventional CEH without symmetry [H.
Goldstein, C. Poole, J. Safko, Classical Mechanics, third ed., Addison-Wesley,
2001]. We also prove that the number of the CEHs is equal to the number of the
generalized coordinates for the FODS, but twice the number of the generalized
coordinates for the SODS. We show that the FODS can only be expressed by the
new CEH, but do not by the conventional CEH, while the SODS can be done by both
the new and the conventional CEHs. As an example, we prove that the nonlinear
Schr\"{o}dinger equation can be expressed with the new CEH in a consistent way.
