  Well-posedness and a number of qualitative properties for solutions to the
Cauchy problem for the following nonlinear diffusion equation with a spatially
inhomogeneous source $$ \partial_tu=\Delta u^m+|x|^{\sigma}u^p, $$ posed for
$(x,t)\in\mathbb{R}^N\times(0,T)$, with exponents $1<p<m$ and $\sigma>0$, are
established. More precisely, we identify the \emph{optimal class of initial
conditions} $u_0$ for which (local in time) existence is ensured and prove
\emph{non-existence of solutions} for the complementary set of data. We
establish then (local in time) \emph{uniqueness and a comparison principle} for
this class of data. We furthermore prove that any non-trivial solution to the
Cauchy problem \emph{blows up in a finite time} $T\in(0,\infty)$ and
\emph{finite speed of propagation} holds true for $t\in(0,T)$: if $u_0\in
L^{\infty}(\mathbb{R}^N)$ is an initial condition with compact support and
blow-up time $T>0$, then $u(t)$ is compactly supported for $t\in(0,T)$. We also
establish in this work the \emph{absence of localization at the blow-up time}
$T$ for solutions stemming from compactly supported data.
