  Cold atmospheric plasma (CAP) displays antimicrobial, antitumor, and
antiviral properties, while the underlying mechanism is seldom clearly
elucidated. In this work, we employed CAP with air-feeding gas to directly
inactivate SARS-CoV-2. The results indicate that the typical SARS-CoV-2
morphological spikes disappeared after plasma treatment and the proteosomes of
SRAS-CoV-2 were modified. In addition, we also evaluated the safety of the air
plasma device in simulating daily life environments through rat experiments. We
evaluated rats' daily physiological behavior, body weight, food consumption,
organ histopathology, blood biochemical indicators, and so on. These results
demonstrate air plasma device is a safe and effective mean prevents virus
transmissions and infections.
