  We developed a novel pathway to highly efficiently synthesize the
[60]Fullerene (C$_{60}$)-Cyclodextrin (CD) complex, which is termed as
solvent-induced reversible recognition. Three kinds of typical complexes,
namely, C$_{60}$-2GUA$^+$-$\alpha$-CD, C$_{60}$-2GUA$^+$-$\beta$-CD and
C$_{60}$-4OH-$\beta$-CD, were synthesized. The chemical structure of all
complexes was fully confirmed by Fourier transform infrared spectroscopy,
Nuclear magnetic resonance (NMR), UV-Vis spectroscopy and the solubility test.
Furthermore, crystalline status and thermal degradation were recorded by X-ray
diffraction and Thermogravimetric analysis, respectively. Both the NMR and
ESI-MS results clearly confirmed the 1:1 complex of C$_{60}$ derivatives with
CD. The pathway overcame the preparation limitation of traditional complex, and
was extended to the prepare $\alpha$-CD containing complex. To the best of our
knowledge, it is the first time to report $\alpha$-CD related complex. The
geometric relation between C$_{60}$ and CD for all the three kinds of complexes
were analyzed. We can achieve high efficiency to obtain solid-state complex
products, which lays the foundation for the widely practical application of
complex and provides enough experimental basis for the advanced application of
C$_{60}$ and CD in supramolecular assembly. Notably, the solvent-induced
reversibility and ionic instability of the complex provides a new possibility
for the molecular recognition-based sensing.
