  Neuronal cells present periodic trains of localized voltage spikes involving
a large amount of different ionic channels. A relevant question is whether this
is a cooperative effect or it could also be an intrinsic property of individual
channels. Here we use a Langevin formulation for the stochastic dynamics of a
pair of Na and K ionic channels. These two channels are simple gated pore
models where a minimum set of degrees of freedom follow standard statistical
physics. The whole system is totally autonomous without any external energy
input, except for the chemical energy of the different ionic concentrations
across the membrane. As a result it is shown that a unique pair of different
ionic channels can sustain membrane potential periodic spikes. The spikes are
due to the interaction between the membrane potential, the ionic flows and the
dynamics of the internal parts (gates) of each channel structures. The spike
involves a series of dynamical steps being the more relevant one the leak of Na
ions. Missing spike events are caused by the altered functioning of specific
model parts. The time dependent spike structure is comparable with experimental
data.
