  In this work, we investigate the problem of finite time blow up as well as
the upper bound estimates of lifespan for solutions to small-amplitude
semilinear wave equations with time dependent damping and potential, and mixed
nonlinearities $c_1 |u_t|^p+c_2 |u|^q$, posed on asymptotically Euclidean
manifolds, which is related to both the Strauss conjecture and the Glassey
conjecture.
