  We disscuss a new nonperturbative mechanism for spin effects in high energy
reactions with hadrons. This mechanism is based on the existence of a large
anomalous quark chromomagnetic moment (AQCM) induced by the nontrivial
topological structure of QCD vacuum. As an example, we estimate the
contribution of this interaction to the single spin asymmetry (SSA) in the
inclusive pion production in the proton-proton scattering. We show that SSA
induced by AQCM is large and its value is in qualitative agreement with
experimental data.
