  We present a novel method for quantifying dependencies in multivariate
datasets, based on estimating the R\'{e}nyi entropy by minimum spanning trees
(MSTs). The length of the MSTs can be used to order pairs of variables from
strongly to weakly dependent, making it a useful tool for sensitivity analysis
with dependent input variables. It is well-suited for cases where the input
distribution is unknown and only a sample of the inputs is available. We
introduce an estimator to quantify dependency based on the MST length, and
investigate its properties with several numerical examples. To reduce the
computational cost of constructing the exact MST for large datasets, we explore
methods to compute approximations to the exact MST, and find the multilevel
approach introduced recently by Zhong et al. (2015) to be the most accurate. We
apply our proposed method to an artificial testcase based on the Ishigami
function, as well as to a real-world testcase involving sediment transport in
the North Sea. The results are consistent with prior knowledge and heuristic
understanding, as well as with variance-based analysis using Sobol indices in
the case where these indices can be computed.
