  We developed a new endogenous approach to reveal subcellular metabolic
contrast in fresh ex vivo tissues taking advantage of the time dependence of
the full field optical coherence tomography interferometric signals. This
method reveals signals linked with local activity of the endogenous scattering
elements which can reveal cells where other imaging techniques fail or need
exogenous contrast agents. We benefit from the micrometric transverse
resolution of full field OCT to image intracellular features. We used this time
dependence to identify different dynamics at the millisecond scale on a wide
range of organs in normal or pathological conditions.
