  More than 300,000 new cases worldwide are being diagnosed with oral cancer
annually. Complexity of oral cancer renders designing drug targets very
difficult. We analyse protein-protein interaction network for the normal and
oral cancer tissue and detect crucial changes in the structural properties of
the networks in terms of the interactions of the hub proteins and the
degree-degree correlations. Further analysis of the spectra of both the
networks, while exhibiting universal statistical behavior, manifest distinction
in terms of the zero degeneracy, providing insight to the complexity of the
underlying system.
