  We study the extended colored Zee-Babu model introducing a vector-like quark
and singlet scalar. The active neutrino mass matrix and muon anomalous magnetic
moment are analyzed, which can be fitted to experimental data satisfying the
constraints from flavor changing neutral current. Then we discuss signature of
our model via vector-like quark production. In addition, the diphoton excess
can be explained with the contribution from vector-like quark
