  Locomotor system disorders affect a vast majority of people at some time in
their life bringing pain, functional limitations, social and economic
implications. Modern medicine cannot offer prevention and effective treatment
for most chronic musculoskeletal conditions, because their etiology and
pathogenesis are unknown. This is due to the lack of systemic understanding of
the locomotor system functioning in both healthy and unhealthy states. Here we
apply systems sciences to analyze the human locomotor system and develop a
general theory that reveals the systemic destructive process in the locomotor
system, linking together all its disorders. The systemic destruction involves
adaptation and self-organization processes in the locomotor system, whose side
effects introduce a positive feedback loop with nervous and vascular
disturbances. Most chronic musculoskeletal conditions are just manifestations
and consequences of this process. On the basis of our theoretical findings, we
developed the world's first technology that effectively counteracts the
systemic destruction and improves the locomotor system state at any age, also
preventing problems in nervous and cardiovascular systems.
