  Recently, the Molecules with ALMA at Planet-forming Scales (MAPS) ALMA Large
Program reported a high number of line emission substructures coincident with
dust rings and gaps in the continuum emission, suggesting a causal link between
these axisymmetric line emission and dust continuum substructures. To test the
robustness of the claimed correlation, we compare the observed spatial overlap
fraction in substructures with that from the null hypothesis, in which the
overlap is assumed to arise from the random placement of line emission
substructures. Our results reveal that there is no statistically significant
evidence for a universal correlation between line emission and continuum
substructures, questioning the frequently-made link between continuum rings and
pressure bumps. The analysis also clearly identifies outliers. The chemical
rings and the dust gaps in MWC 480 appear to be strongly correlated
(${>}4\sigma$), and the gaps in the CO isotopologues tend to moderately
(${\sim}3\sigma$) correlate with dust rings.
