  We investigate the attempt using flavor violation gauge interaction in the up
sector to explain the LHCb recently observed large $\Delta A_{CP}$
($A_{CP}(D^{0}\to K^{+}K^{-})-A_{CP}(D^{0}\to \pi^{+}\pi^{-})$). We study an
Abelian model that only right-handed up quarks is charged under it and the 1-3
coupling is maximized. The simultaneous 1-3 2-3 mixing is realized by a quark
mixing of 1-2 generation. Given the easy identification of top quark, the model
can be directly tested by $\Delta F=1$ and $\Delta F=2$ processes at the hadron
colliders as associated top production $g c \to t Z^{\prime}$ or same-sign top
scattering $u u\to t t$. The direct search bounds are still consistent with the
assumption that $ut$ and $ct$ couplings are equal but the same-sign top
scattering bound is expected to be reached very soon. However, since there is
no CKM-like suppression, the corresponding parameter space for generating
$\Delta A_{CP}$ is completely excluded by the $D^{0}-\bar{D}^{0}$ mixing. We
conclude that the up FCNC type models cannot explain the $\Delta A_{CP}$ while
to be consistent with the $D^{0}-\bar{D}^{0}$ mixing constraint at the same
time. On the other hand, a model as SM with fourth family extension has better
chance to explain the large $\Delta A_{CP}$ consistently.
