  We present a non-parametric prognostic framework for individualized event
prediction based on joint modeling of both longitudinal and time-to-event data.
Our approach exploits a multivariate Gaussian convolution process (MGCP) to
model the evolution of longitudinal signals and a Cox model to map
time-to-event data with longitudinal data modeled through the MGCP. Taking
advantage of the unique structure imposed by convolved processes, we provide a
variational inference framework to simultaneously estimate parameters in the
joint MGCP-Cox model. This significantly reduces computational complexity and
safeguards against model overfitting. Experiments on synthetic and real world
data show that the proposed framework outperforms state-of-the art approaches
built on two-stage inference and strong parametric assumptions.
