  Two crucial for the breakdown of the master equation arguments are put
forward. The first one is related to the violence of a fundamental requirement
to the notion of state (thermodynamical) variable, namely: a state variable is
defined provided it is insensitive to the particularities of the
spatio-temporal configurations upon which the averaging over the dynamical
variables proceeds. The second one is related to a ubiquitous divergence of the
scattering length in the low-energy limit. In turn, it makes the rates of all
the elementary processes divergent as well. Though radically novel viewpoints
to the low-energy limit and to the evolution ensure the boundedness of the
rates and hold the notion of a state variable available, the master equation
remains inappropriate.
