  Aims: We study the blazar nature of the high-redshift Flat-Spectrum Radio
Quasar PKS 2149-306 (z = 2.345) by investigating its long-term behavior.
Methods: We analyzed all publicly available optical-to-X-ray observations
performed by XMM-Newton, Swift, and INTEGRAL. Conclusions: PKS 2149-306 is one
of four blazars at z>2 that have been observed in the hard-X-ray regime with
both the BAT and ISGRI instruments. Observations acquired almost 1 year apart
in the 60-300 keV energy band in the object rest frame, exhibit no noticeable
change in spectral slope associated with a flux variation of more than a factor
of two. Swift data appear to show a roll-off below ~1 keV, which becomes
increasingly evident during a ~3-day time-frame, that can be explained as the
natural spectral break caused by the Inverse Compton onset. The broad-band
spectra allow us to identify two different states. The SED modeling suggests
that they can be interpreted by only a change in the bulk Lorentz factor of the
jet.
