  Drug repurposing is an unconventional approach that is used to investigate
new therapeutic aids of existing and shelved drugs. Recent advancement in
technologies and the availability of the data of genomics, proteomics,
transcriptomics, etc., and with the accessibility of large and reliable
database resources, there are abundantly of opportunities to discover drugs by
drug repurposing in an efficient manner. The recent pandemic of SARS-COV-2,
that caused the death of 6,245,750 human beings to date, has tremendously
increase the exceptional usage of bioinformatics tools in interpreting the
molecular characterizations of viral infections. In this paper, we have
employed various bioinformatics tools such as AutoDock-Vina, PyMol etc. We have
found a leading drug candidate Cepharanthine that has shown better results and
effectiveness than recently used antiviral drug candidates such as Favipiravir,
IDX184, Remedesivir, Ribavirin and etc. This paper has analyzed Cepharanthine
potential therapeutic importance as a drug of choice in managing COVID-19
cases. It is anticipated that proposed study would be beneficial for
researchers and medical practitioners in handling SARS-CoV-2 and its variant
related diseases.
