  In the present paper we investigate the influence of inhomogeneities in the
dynamics and stability of DNA open states, modeled as propagating solitons in
the spirit of a Generalized Yakushevish Model. It is a direct consecuence of
our model that there exists a critical distance between the soliton's center of
mass and the inhomogeneity at which the interaction between them can change the
stability of the open state.Furtherly from this results was derived a
renormalized potential funtion.
