  Spatial and spatio-temporal model checking techniques have a wide range of
application domains, among which large scale distributed systems and signal and
image analysis. We explore a new domain, namely (semi-)automatic contouring in
Medical Imaging, introducing the tool VoxLogicA which merges the
state-of-the-art library of computational imaging algorithms ITK with the
unique combination of declarative specification and optimised execution
provided by spatial logic model checking. The result is a rapid, logic based
analysis development methodology. The analysis of an existing benchmark of
medical images for segmentation of brain tumours shows that simple VoxLogicA
analysis can reach state-of-the-art accuracy, competing with best-in-class
algorithms, with the advantage of explainability and replicability.
Furthermore, due to a two-orders-of-magnitude speedup compared to the existing
general-purpose spatio-temporal model checker topochecker, VoxLogicA enables
interactive development of analysis of 3D medical images, which can greatly
facilitate the work of professionals in this domain.
