  In a D-brane model of space-time foam, there are contributions to the dark
energy that depend on the D-brane velocities and on the density of D-particle
defects. The latter may also reduce the speeds of photons linearly with their
energies, establishing a phenomenological connection with astrophysical probes
of the universality of the velocity of light. Specifically, the cosmological
dark energy density measured at the present epoch may be linked to the apparent
retardation of energetic photons propagating from nearby AGNs. However, this
nascent field of `D-foam phenomenology' may be complicated by a dependence of
the D-particle density on the cosmological epoch. A reduced density of
D-particles at redshifts z ~ 1 - a `D-void' - would increase the dark energy
while suppressing the vacuum refractive index, and thereby might reconcile the
AGN measurements with the relatively small retardation seen for the energetic
photons propagating from GRB 090510, as measured by the Fermi satellite.
