  The statistical properties of intra-chromosome maps obtained by a genome-wide
chromosome conformation capture method (Hi-C) are described in the framework of
the hierarchical crumpling model of heteropolymer chain with quenched disorder
in the primary sequence. We conjecture that the observed Hi-C maps are
statistical averages over many different ways of hierarchical genome folding,
and show that the existence of quenched primary structure coupled with
hierarchical folding can induce the observed fine structure of intra-chromosome
contact maps.
