  We derived an ordinary differential equation model to capture the disease
dynamics during blood-stage malaria. The model was directly derived from an
earlier age-structured partial differential equation model. The original model
was simplified due to experimental constraints. Here we calibrated the
simplified model with experimental data using a multiple objective genetic
algorithm. Through the calibration process, we quantified the removal of
healthy red blood cells and the the preferential infection of reticulocytes
during \textit{Plamodium cynomolgi} infection of \textit{Macaca mulatta}. The
calibration of our model also revealed the existence of host erythropoietic
response prior to blood stage infection.
