  We propose a new approach to understand the time-dependent temperature
increasing process of gold-silica core-shell nanoparticles injected into
chicken tissues under near-infrared laser irradiation. Gold nanoshells strongly
absorb near-infrared radiations and efficiently transform absorbed energy into
heat. Temperature rise given by experiments and numerical calculations based on
bioheat transfer are in good agreement. Our work improves the analysis of a
recent study [Richardson et al., Nano Lett. 9, 1139 (2009)] by including
effects of the medium perfusion on temperature increase. The theoretical
analysis can also be used to estimate the distribution of nanoparticles in
experimental samples and provide a relative accuracy prediction for the
temperature profile of new systems. This methodology would provide a novel and
reliable tool for speeding up photothermal investigations and designing
state-of-the-art photothermal devices.
