  We discuss a possible interpretation of the $750$ GeV diphoton resonance,
recently reported at the LHC, within a class of $SU(2)_L\times SU(2)_R\times
SU(4)$ models with gauge coupling unification. The unification is imposed by
the underlying non-commutative geometry (NCG), which in these models is
extended to a left-right symmetric completion of the Standard Model (SM).
Within such \textit{unified} $SU(2)_L\times SU(2)_R\times SU(4)$ models the
Higgs content is restrictively determined from the underlying NCG, instead of
being arbitrarily selected. We show that the observed cross sections involving
the $750$ GeV diphoton resonance could be realized through a SM singlet scalar
field accompanied by colored scalars, present in these unified models. In view
of this result we discuss the underlying rigidity of these models in the NCG
framework and the wider implications of the NCG approach for physics beyond the
SM.
