  Microarrays are made it possible to simultaneously monitor the expression
profiles of thousands of genes under various experimental conditions.
Identification of co-expressed genes and coherent patterns is the central goal
in microarray or gene expression data analysis and is an important task in
bioinformatics research. Feature selection is a process to select features
which are more informative. It is one of the important steps in knowledge
discovery. The problem is that not all features are important. Some of the
features may be redundant, and others may be irrelevant and noisy. In this work
the unsupervised Gene selection method and Enhanced Center Initialization
Algorithm (ECIA) with K-Means algorithms have been applied for clustering of
Gene Expression Data. This proposed clustering algorithm overcomes the
drawbacks in terms of specifying the optimal number of clusters and
initialization of good cluster centroids. Gene Expression Data show that could
identify compact clusters with performs well in terms of the Silhouette
Coefficients cluster measure.
