  The aftermath of influenza infection is determined by a complex set of
host-pathogen interactions, where genomic variability on both viral and host
sides influences the final outcome. Although there exists large body of
literature describing influenza virus variability, only a very small fraction
covers the issue of host variance. The goal of this review is to explore the
variability of host genes responsible for host-pathogen interactions, paying
particular attention to genes responsible for the presence of sialylated
glycans in the host endothelial membrane, mucus, genes used by viral immune
escape mechanisms, and genes particularly expressed after vaccination, since
they are more likely to have a direct influence on the infection outcome.
