  We present JWST imaging from 2$\mu$m to 21$\mu$m of the edge-on
protoplanetary disk around the embedded young star IRAS04302+2247. The
structure of the source shows two reflection nebulae separated by a dark lane.
The source extent is dominated by the extended filamentary envelope at
$\sim$4.4$\mu$m and shorter wavelengths, transitioning at 7$\mu$m and longer
wavelengths to more compact lobes of scattered light from the disk itself. The
dark lane thickness does not vary significantly with wavelength, which we
interpret as an indication for intermediate-sized ($\sim10\mu$m) grains in the
upper layers of the disk. Intriguingly, we find that the brightest nebula of
IRAS40302 switches side between 12.8$\mu$m and 21$\mu$m. We explore the effect
of a tilted inner region on the general appearance of edge-on disks. We find
that radiative transfer models of a disk including a tilted inner region can
reproduce an inversion in the brightest nebula. In addition, for specific
orientations, the model also predicts strong lateral asymmetries, which can
occur for more than half possible viewing azimuths. A large number of edge-on
protoplanetary disks observed in scattered light show such lateral asymmetries
(15/20), which suggests that a large fraction of protoplanetary disks might
host a tilted inner region. Stellar spots may also induce lateral asymmetries,
which are expected to vary over a significantly shorter timescale. Variability
studies of edge-on disks would allow to test the dominant scenario for the
origin of these asymmetries.
