  We study the joint effect of thermal bath fluctuations and an external noise
tuning activity of cytotoxic cells on the triggered immune response in a
growing cancerous tissue. The immune response is assumed to be primarily
mediated by effector cells that develop a cytotoxic activity against the
abnormal tissue. The kinetics of such a reaction is represented by an
enzymatic-like Michaelis-Menten two step process. Effective free-energy surface
for the process is further parametrized by the fluctuating energy barrier
between the states of high and low concentration of cancerous cells. By
analyzing the far from equilibrium escape problem across the fluctuating
potential barrier, we determine condtions of the most efficient decay kinetics
of the cancer cell-population in the presence of dichotomously fluctuating
concentration of cytotoxic cells.
