  Let $\textbf{H} = ((H, F^{\bullet}), L)$ be a polarized variation of Hodge
structure on a smooth quasi-projective variety $U.$ By M. Saito's theory of
mixed Hodge modules, the variation of Hodge structure $\textbf{H}$ can be
viewed as a polarized Hodge module $\mathcal{M} \in HM(U).$ Let $X$ be a
compactification of $U,$ and $j:U \hookrightarrow X$ is the natural map. In
this paper, we use local cohomology with mixed Hodge module theory to study
$j_{+}\mathcal{M} \in D^{b}MHM(X).$ In particular, we study the graded pieces
of the de Rham complex $Gr^{F}_{p}DR(j_{+}\mathcal{M}) \in D^{b}_{coh}(X),$ and
the Hodge structure of $H^{i}(U,L)$ for $i$ in sufficiently low degrees.
