  Quiver quantum mechanics is invariant under Seiberg duality. A mathematical
consequence is that the cohomology of the Higgs branch moduli space is
invariant under mutations of the quiver. The Coulomb branch formula, on the
other hand, conjecturally expresses the Poincar\'e / Dolbeault polynomial of
the Higgs branch moduli space in terms of certain quantities known as
single-centered indices. In this work we determine the transformations of these
single-centered indices under mutations. Moreover, we generalize these
mutations to quivers whose nodes carry single-centered indices different from
unity. Although the Higgs branch description of these generalized quivers is
currently unknown, the Coulomb branch formula is conjectured to be invariant
under generalized mutations.
