  Signatures of "mesoscopic Coulomb blockade" are reported for quantum dots
with one fully transmitting point-contact lead, T1 = 1, T2 << 1. Unlike Coulomb
blockade (CB) in weak-tunneling devices (T1, T2 << 1), one-channel CB is a
mesoscopic effect requiring quantum coherence. Several distinctive features of
mesoscopic CB are observed, including a reduction in CB upon breaking
time-reversal symmetry with a magnetic field, relatively large fluctuations of
peak position as a function of magnetic field, and strong temperature
dependence on the scale of the quantum level spacing.
