  Blood clots occur in the human body when they are required to prevent
bleeding. In pathological states such as diabetes and sickle cell disease,
blood clots can also form undesirably due to hypercoagulable plasma conditions.
With the continued effort in developing fibrin therapies for potential
life-saving solutions, more mechanical modeling is needed to understand the
properties of fibrin structures with inclusions. In this study, a fibrin matrix
embedded with magnetic micro particles (MMPs) was subjected to a magnetic field
to determine the magnitude of the required force to create plastic deformation
within the fibrin clot. Using finite element (FE) analysis, we estimated the
magnetic force from an electromagnet at a sample space located approximately 3
cm away from the coil center. This electromagnetic force coupled with gravity
was applied on a fibrin mechanical system with MMPs to calculate the stresses
and displacements. Using appropriate coil parameters, it was determined that
application of a magnetic field of 730 A/m on the fibrin surface was necessary
to achieve an electromagnetic force of 36 nN (to engender plastic deformation).
