  The UK Office for National Statistics (ONS) publish a regular infection
survey that reports data on positive RT-PCR test results for SARS-COV-2 virus.
This survey reports that a large proportion of positive test results may be
based on the detection of a single target gene rather than on two or more
target genes as required in the manufacturer instructions for use, and by the
WHO in their emergency use assessment. Without diagnostic validation, for both
the original virus and any variants, it is not clear what can be concluded from
a positive test resulting from a single target gene call, especially if there
was no confirmatory testing. Given this, many of the reported positive results
may be inconclusive, negative or from people who suffered past infection for
SARS-COV-2.
