  A texture-zeros is an approach to reduce the number of free parameters in
Yukawa couplings and it is one of the most attractive ones. In our paper, we
discuss the origin of zero-structure in texture-zeros by S_3 flavor symmetry
approach. Some of electroweak doublet Higgs fields have vanishing vacuum
expectation value(VEV) which leads to vanishing elements in quark and lepton
mass matrices. Then, the structure of supersymmetric scalar potential is
analyzed and Higgs fields have non-trivial S_3 charges. As a prediction of our
paper, a lower bound of a MNS matrix element, U_{e3} \geq 0.04, is obtained.
The suppression of flavor-changing neutral currents(FCNC) mediated by the Higgs
fields is discussed and lower bounds of the Higgs masses are derived.
