  We consider the current results in search for and description of temporal
variations of fundamental physical constants (FPCs) obtained under laboratory
and astrophysical conditions. On the basis of fixed values of base constants,
those FPCs have been chosen that can exhibit variations of greatest interest
from the viewpoints of physics and metrology. An analysis of the current data
concerning these constants is performed, and estimates of their variations on
large time scales are presented. We point out the significance of studying
long-term FPC variations for both practical and fundamental metrology.
