  Massive numbers of meta-analysis studies are being published. A Google
Scholar search of "systematic review and meta-analysis" returns about 452k hits
since 2014. The search was done on Jan 14, 2019. There is a need to have some
way to judge the reliability of a positive claim made in a meta-analysis that
uses observational studies. Our idea is to examine the quality of the
observational studies used in the meta-analysis and to examine the
heterogeneity of those studies. We provide background information and examples:
a listing of negative studies, a simulation of p-value plots, and multiple
examples of p-value plots.
