  An effective biosensor based on two-dimensional (2D) Co-ZIF-L nanosheets for
sensitive electrochemical non-enzymatic glucose detection is developed, which
exhibits high electrocalalytic activities towards glucose due to the ordered
porous structure as well as ultrahigh specific surface area. The fabricated
Co-ZIF-L nanosheets electrodes present an outstanding performance with higher
sensitivity of 769.5 *10$^{-6}$ A mM$^{-1}$ cm$^{-2}$ and lower detect limit of
90.4 nM, while the constructed 3D ZIF-67 nanoparticles electrodes show a weaker
sensitivity of 697.4 *10$^{-6}$ A mM$^{-1}$ cm$^{-2}$ and a limited detection
range from 2 *10$^{-6}$ M to 414 *10$^{-6}$ M. Furthermore, the Co-ZIF-L based
non-enzymatic glucose biosensors possess an acceptable selectivity, long-term
stability as well as reproducibility. This work may offer a new approach to
develop 2D ZIF nanosheets as a potential candidate in electrochemical
biosensors.
