  UniFrac is a family of distance metrics over microbial abundances, that take
taxonomic relatedness into account. Current tools and libraries for calculating
UniFrac have specific requirements regarding the user's technical expertise,
operating system, and pre-installed software, which might exclude potential
users. FrackyFrac is a native command-line tool that can run on any platform
and has no requirements. It can also generate the phylogenetic trees required
for the calculation. We show that FrackyFrac's performance is on par with
currently existing implementations. FrackyFrac can make UniFrac accessible to
researchers who may otherwise skip it due to the effort involved, and it can
simplify analysis pipelines for those who already use it.
