  The patient must be given an adequate amount of propofol for safe surgery
since overcapacity and low capacity cause accidents. However, the sensitivity
of propofol varies from patient to patient, making it very difficult to
determine the propofol requirements for anesthesia. This paper aims to propose
a neurophysiological predictor of propofol requirements based on the
preoperative electroencephalogram (EEG). We exploited the canonical correlation
analysis that infers the amount of information on the propofol requirements.
The results showed that the preoperative EEG included the factor that could
explain the propofol requirements. Specifically, the frontal and posterior
regions had crucial information on the propofol requirements. Moreover, there
was a significantly different power in the frontal and posterior regions
between baseline and unconsciousness periods, unlike the alpha power in the
central region. These findings showed the potential that preoperative EEG could
predict the propofol requirements.
