  AGB variables, particularly the large amplitude Mira type, are a vital step
on the distance scale ladder. They will prove particularly important in the era
of space telescopes and extremely large ground-based telescopes with adaptive
optics, which will be optimized for infrared observing. Our current
understanding of the distances to these stars is reviewed with particular
emphasis on improvements that came from Hipparcos as well as on recent work on
Local Group galaxies. In addition to providing the essential calibration for
extragalactic distances Gaia may also provide unprecedented insight into the
poorly understood mass-loss process itself.
