  Virtual reality is a powerful tool with the ability to immerse a user within
a completely external environment. This immersion is particularly useful when
visualizing and analyzing interactions between small organic molecules,
molecular inorganic complexes, and biomolecular systems such as redox proteins
and enzymes. A common tool used in the biomedical community to analyze such
interactions is the APBS software, which was developed to solve the equations
of continuum electrostatics for large biomolecular assemblages. Numerous
applications exist for using APBS in the biomedical community including
analysis of protein ligand interactions and APBS has enjoyed widespread
adoption throughout the biomedical community. Currently, typical use of the
full APBS toolset is completed via the command line followed by visualization
using a variety of two-dimensional external molecular visualization software.
This process has inherent limitations: visualization of three-dimensional
objects using a two-dimensional interface masks important information within
the depth component. Herein, we have developed a single application,
UnityMol-APBS, that provides a dual experience where users can utilize the full
range of the APBS toolset, without the use of a command line interface, by use
of a simple \ac{GUI} for either a standard desktop or immersive virtual reality
experience.
