  Cosmic-ray (CR) anti-nuclei are often considered as important observables for
dark matter (DM) indirect detections at low kinetic energies below GeV per
nucleon. Since the primary CR fluxes drop quickly towards high energies, the
secondary anti-nuclei in CR are expected to be significantly suppressed in high
energy regions ($\gtrsim 100$ GeV per nucleon). If DM particles are heavy, the
annihilation productions of DM can be highly boosted, thus the fluxes of
anti-nuclei produced by DM annihilations may exceed the secondary background at
high energies, which opens a high energy window for DM indirect detections. We
investigate the possibility of detecting heavy DM particles which annihilate
into high energy anti-nuclei. We use Monte-Carlo generators $\texttt{PYTHIA}$,
$\texttt{EPOS-LHC}$ and $\texttt{DPMJET}$ and the coalescence model to simulate
the production of anti-nuclei, and constrain the DM annihilation cross sections
by using the AMS-02 and HAWC antiproton data and the HESS galactic center
gamma-ray data. We find that the conclusion depends on the choice of DM density
profiles. For the "Cored" type profile with a DM particle mass $\gtrsim 10$
TeV, the contributions from DM annihilations can exceed the secondary
background in high energy regions, which opens the high energy window. While
for the "Cuspy" type profile, the excess disappears.
