  We investigate the QCD ghost model of dark energy in the framework of
Brans-Dicke cosmology. First, we study the non-interacting ghost dark energy in
a flat Brans-Dicke theory. In this case we obtain the EoS and the deceleration
parameters and a differential equation governing the evolution of ghost energy
density. Interestingly enough, we find that the EoS parameter of the
non-interacting ghost dark energy can cross the phantom line ($w_D=-1$)
provided the parameters of the model are chosen suitably. Then, we generalize
the study to the interacting ghost dark energy in both flat and non-flat
Brans-Dicke framework and find out that the transition of $w_D$ to phantom
regime can be more easily achieved for than when resort to the Einstein field
equations is made.
