  Connected and autonomous vehicle (CAV) networks face several challenges, such
as low throughput, high latency, and poor localization accuracy. These
challenges severely impede the implementation of CAV networks for immersive
metaverse applications and driving safety in future 6G wireless networks. To
alleviate these issues, integrated sensing and communications (ISAC) is
envisioned as a game-changing technology for future CAV networks. This article
presents a comprehensive overview on the application of ISAC techniques in
vehicle-to-infrastructure (V2I) networks. We cover the general system
framework, representative advances, and a detailed case study on using the 5G
New Radio (NR) waveform for sensing-assisted communications in V2I networks.
Finally, we highlight open problems and opportunities in the field.
