  We study the level of primordial non-Gaussianity in slow-roll two-field
inflation. Using an analytic formula for the nonlinear parameter f_nl in the
case of a sum or product separable potential, we find that it is possible to
generate significant non-Gaussianity even during slow-roll inflation with
Gaussian perturbations at Hubble exit. In this paper we give the general
conditions to obtain large non-Gaussianity and calculate the level of
fine-tuning required to obtain this. We present explicit models in which the
non-Gaussianity at the end of inflation can exceed the current observational
bound of |f_nl|<100.
