  The efficiency of dipole-dipole coupling driven coherence transfer
experiments in solid-state NMR spectroscopy of powder samples is limited by
dispersion of the orientation of the internuclear vectors relative to the
external magnetic field. Here we introduce general design principles and
resulting pulse sequences that approach full polarization transfer efficiency
for all crystallite orientations in a powder in magic-angle-spinning
experiments. The methods compensate for the defocusing of coherence due to
orientation dependent dipolar coupling interactions and inhomogeneous
radio-frequency fields. The compensation scheme is very simple to implement as
a scaffold (comb) of compensating pulses in which the pulse sequence to be
improved may be inserted. The degree of compensation can be adjusted and should
be balanced as a compromise between efficiency and length of the overall pulse
sequence. We show by numerical and experimental data that the presented
compensation protocol significantly improves the efficiency of known dipolar
recoupling solid-state NMR experiment.
