  Bacterial chemotaxis is controlled by the conformational changes of the
receptors, in response to the change of the ambient chemical concentration. In
a statistical mechanical approach, the signalling due to the conformational
changes is a thermodynamic average quantity, dependent on the temperature and
the total energy of the system, including both ligand-receptor interaction and
receptor-receptor interaction. This physical theory suggests to biology a new
understanding of cooperation in ligand binding and receptor signalling
problems. How much experimental support of this approach can be obtained from
the currently available data? What are the parameter values? What is the
practical information for experiments? Here we make comparisons between the
theory and recent experimental results. Although currently comparisons can only
be semi-quantitative or qualitative, consistency is clearly shown. The theory
also helps to sort a variety of data.
