  We compute photoionization models for the giant extragalactic H II region NGC
5461, and compare their predictions to several observational constraints. Since
we aim at reproducing not only the global properties of the region, but its
local structure also, the models are constrained to reproduce the observed
density profile, and our analysis takes into consideration the bias introduced
by the shapes and sizes of the slits used by different observers. We find that
an asymmetric nebula with a gaussian density distribution, powered by a young
burst of 3.1 Myr, satisfactorily reproduces most of the constraints, and that
the star-formation efficiency inferred from the model agrees with current
estimates. Our results strongly depend on the assumed density law, since
constant density models overestimate the hardness of the ionizing field,
affecting the deduced properties of the central stellar cluster. We illustrate
the features of our best model, and discuss the possible sources of errors and
uncertainties affecting the outcome of this type of studies.
