  Histopathology plays a central role in diagnosis of many diseases including
solid cancers. Efforts are underway to transform this subjective art form to an
objective and quantitative science. Coherent Raman imaging (CRI), a label-free
imaging modality with sub-cellular spatial resolution and molecule-specific
contrast possesses characteristics which could support the
qualitative-to-quantitative transition of histopathology. In this work we
briefly survey major themes related to modernization of histopathology, review
applications of CRI to histopathology and, finally, discuss potential roles for
CRI in the transformation of histopathology that is already underway.
