  The Grothendieck--Serre conjecture asserts that on a regular local ring,
there is no nontrivial reductive torsor that becomes trivial over the fraction
field. This conjecture is answered in the affirmative in the equicharacteristic
case but is still open in the mixed characteristic case. In this article, we
establish its generalized version over Prufer bases for constant reductive
group schemes. In particular, the Noetherian restriction of our main result
settles a new case of the Grothendieck--Serre conjecture. Subsequently, we use
this as a key input to resolve the variant of Bass--Quillen conjecture for
torsors under constant reductive group schemes in our Pruferian context. Along
the way, inspired by the recent preprint of Cesnavicius, we also prove several
versions of the Nisnevich conjecture in our context.
