  The presence of chirality in the main molecules of life may well be not just
a structural artifact, but of pure biological advantage. The possibility of the
existence of a phenomenon of a special mode of interaction, labeled as "chiral
interaction" (CI), for which structural chirality is a necessary condition, is
the main reason for such an advantage. In order to demonstrate such a
possibility, macroscopic chiral devices are introduced and presented as
analogies for such an interaction. For this purpose it is important to make a
clear distinction between geometric and physical chiralities, where the latter
are capable to perform chiral interactions with various media. Apart from
chirality, a few other structural elements are required. In particular, the
presence of an interface that separates between the chiral device and the
medium with which it is interacting. The physical chirality is build into this
very interface where chiral interaction is taking place. On a molecular level,
soluble proteins in particular, the active medium is the presence of random
ionic motion in the aqueous solvent. As a result of chiral interaction a
certain perturbation, or current, is generated and flowing along the coils of $
\alpha$-helix structure in one preferred direction out of two possible ones. A
model for such a chiral interaction is presented and a few significant
consequences are pointed out. In particular, it is important to emphasize the
time-irreversible feature of chiral interaction, which leads to its non-ergodic
nature that is to be considered a necessary condition for evolutionary
processes in biomolecules. There exists an experimental result by Careri et al.
who found a clear linkage between the free protonic motion in the hydration
layer of protein s and their enzymatic activity.
