  Let $K_v^*$ denote the complete graph $K_v$ if $v$ is odd and $K_v-I$, the
complete graph with the edges of a 1-factor removed, if $v$ is even. Given
non-negative integers $v, M, N, \alpha, \beta$, the Hamilton-Waterloo problem
asks for a $2$-factorization of $K^*_v$ into $\alpha$ $C_M$-factors and $\beta$
$C_N$-factors. Clearly, $M,N\geq 3$, $M\mid v$, $N\mid v$ and $\alpha+\beta =
\lfloor\frac{v-1}{2}\rfloor$ are necessary conditions.
  Very little is known on the case where $M$ and $N$ have different parities.
In this paper, we make some progress on this case by showing, among other
things, that the above necessary conditions are sufficient whenever $M|N$,
$v>6N>36M$, and $\beta\geq 3$.
