  We propose a novel pathology-sensitive deep learning model (PS-DeVCEM) for
frame-level anomaly detection and multi-label classification of different colon
diseases in video capsule endoscopy (VCE) data. Our proposed model is capable
of coping with the key challenge of colon apparent heterogeneity caused by
several types of diseases. Our model is driven by attention-based deep multiple
instance learning and is trained end-to-end on weakly labeled data using video
labels instead of detailed frame-by-frame annotation. The spatial and temporal
features are obtained through ResNet50 and residual Long short-term memory
(residual LSTM) blocks, respectively. Additionally, the learned temporal
attention module provides the importance of each frame to the final label
prediction. Moreover, we developed a self-supervision method to maximize the
distance between classes of pathologies. We demonstrate through qualitative and
quantitative experiments that our proposed weakly supervised learning model
gives superior precision and F1-score reaching, 61.6% and 55.1%, as compared to
three state-of-the-art video analysis methods respectively. We also show our
model's ability to temporally localize frames with pathologies, without frame
annotation information during training. Furthermore, we collected and annotated
the first and largest VCE dataset with only video labels. The dataset contains
455 short video segments with 28,304 frames and 14 classes of colorectal
diseases and artifacts. Dataset and code supporting this publication will be
made available on our home page.
