  We present a technique for estimating the number of future neutrinoless
double-beta decay results using several distinct nuclei to optimize the physics
reach of upcoming experiments. We use presently available matrix element
calculations and simulated sets of predicted neutrinoless double-beta decay
measured rates in multiple isotopes to estimate the required precision and
number of experiments to discern the underlying physics governing the mechanism
of the process. Our results indicate that 3 (4) experimental results with total
uncertainty (statistical, systematic, theoretical) of less than ~20% (~40%) can
elucidate the underlying physics. If the theoretical (i.e. matrix element)
uncertainty contribution is below ~18%, then 3-4 experimental results of ~20%
precision (statistical and systematic) are required. These uncertainty goals
can be taken as guidance for the upcoming theoretical and experimental
programs.
