  A brief review of problems, arising in the study of the beta-deformation,
also known as "refinement", which appears as a central difficult element in a
number of related modern subjects: beta \neq 1 is responsible for deviation
from free fermions in 2d conformal theories, from symmetric omega-backgrounds
with epsilon_2 = - epsilon_1 in instanton sums in 4d SYM theories, from
eigenvalue matrix models to beta-ensembles, from HOMFLY to super-polynomials in
Chern-Simons theory, from quantum groups to elliptic and hyperbolic algebras
etc. The main attention is paid to the context of AGT relation and its possible
generalizations.
