  Deep inelastic scattering data on $F_2$ structure function from various
fixed-target experiments were analyzed in a nonsinglet approximation in the
MSbar and DIS scheme. The study of high statistics deep inelastic scattering
data provided by BCDMS, SLAC and NMC collaborations, was carried out using a
combined analysis. The application of the DIS scheme leads to the resummation
of contributions that are important for large x values. It is found that using
the DIS scheme does not significantly change the strong coupling constant
itself but does strongly change the values of the twist-four corrections.
