  We have studied implications of the generic lopsided mass matrix of the
charged leptons by taking the SU(5) GUT relation in the nearest-neighbor
interaction (NNI) basis. We have found four interesting relations among the
lepton mixings and the quark ones, which are independent of details of the
model. These relations are discussed by using the experimental data. We have
also discussed the relation between U_{e2} and U_{e3} incuding the contribution
from the neutrino mass matrix. We have presented the probable value U_{e3}=0.05
\sim 0.16, which is independent of the solar neutrino solutions. The CP
violating quantity J_{CP} is also discussed.
