  We present a measurement of the branching fraction for the
doubly-Cabibbo-suppressed decay D+ to K+ pi0, using 281 pb-1 of data
accumulated with the CLEO-c detector on the psi(3770) resonance. We find B(D+
to K+ pi0) = (2.28 +- 0.36 +- 0.15 +- 0.08) times 10^{-4}, where the first
uncertainty is statistical, the second is systematic, and the last error is due
to the uncertainty in the reference mode branching fraction.
