  The flow simulation in alveolar region is imperative in understanding
transport of particles and designing aerosol drug delivery systems. Air flow is
dependent on alveolar geometry and ventilation conditions. In this work a three
dimensional honey-comb like geometry is constructed. A fluid-structure analysis
is performed to study normal breathing airflow. Mechanical properties of
alveolar wall tissue play an important role in the deformation of alveoli. We
have used three distinct material models, linear, non-linear isotropic elastic
and viscoelastic, in order to simulate the mechanical behavior of alveolar wall
tissue and air flow simulation in it. Our simulation shows that linear and
non-linear elastic models cannot describe alveolar tissue behavior as well as
viscoelastic.
