  Background: The secure management of sensitive clinical data, particularly
human genomics data, has become a critical requirement in modern biomedical
research. Although the necessary software and algorithms are readily available,
their use by non-IT experts poses significant challenges.
  Methods: We developed dabih, an open-source web application specifically
designed to facilitate user-friendly encrypted data management. dabih enables
web-based uploading, storing, sharing, and downloading of sensitive data in any
format. Its approach to data security involves a two-stage envelope encryption
process. We combine symmetric-key encryption for data and public-key encryption
as key encapsulation mechanism. The private key necessary for decrypting the
data remains exclusively on the owner's device. Thus, accessing data is
impossible without explicit permission from the keyholder.
  Results: dabih is available open-source on GitHub
https://github.com/spang-lab/dabih, as ready to use containers on docker hub
and includes a command line interface and a graphical bulk upload tool as
pre-built binaries. Documentation is available as part of the web application.
  Conclusions: dabih enables everyone to use strong cryptography for their
data, while being just as simple to use as other, non-encrypted, data storage
solutions. All the cryptography occurs seamlessly in the background as users
interact with a secure web portal, simply by dragging and dropping files.
