  We extend the off-diagonal geometric phase [Phys. Rev. Lett. {\bf 85}, 3067
(2000)] to mixed quantal states. The nodal structure of this phase in the qubit
(two-level) case is compared with that of the diagonal mixed state geometric
phase [Phys. Rev. Lett. {\bf 85}, 2845 (2000)]. Extension to higher dimensional
Hilbert spaces is delineated. A physical scenario for the off-diagonal mixed
state geometric phase in polarization-entangled two-photon interferometry is
proposed.
