  In this work we study the influence of populations mobility on the spread of
a vector-borne disease. We focus on the chikungunya epidemic event that
occurred in 2005-2006 on the R\'eunion Island, Indian Ocean, France, and
validate our models with real epidemic data from the event. We propose a
metapopulation model to represent both a high-resolution patch model of the
island with realistic population densities and also mobility models for humans
(based on real-motion data) and mosquitoes. In this metapopulation network, two
models are coupled: one for the dynamics of the mosquito population and one for
the transmission of the disease. A high-resolution numerical model is created
out from real geographical, demographical and mobility data. The Island is
modeled with an 18 000-nodes metapopulation network. Numerical results show the
impact of the geographical environment and populations' mobility on the spread
of the disease. The model is finally validated against real epidemic data from
the R\'eunion event.
