  We introduce operator-valued twisted Araki-Woods algebras. These are
operator-valued versions of a class of second quantization algebras that
includes $q$-Gaussian and $q$-Araki-Woods algebras and also generalize
Shlyakhtenko's von Neumann algebras generated by operator-valued semicircular
variables. We develop a disintegration theory that reduces the isomorphism type
of operator-valued twisted Araki-Woods algebras over type I factors to the
scalar-valued case. Moreover, these algebras come with a natural weight, and we
characterize its modular theory. We also give sufficient criteria that
guarantee that factoriality of these algebras.
