  In the last two decades, functional magnetic resonance imaging (fMRI) has
emerged as one of the most effective technologies in clinical research of the
human brain. fMRI allows researchers to study healthy and pathological brains
while they perform various neuropsychological functions. Beyond task-related
activations, the human brain has some intrinsic activity at a task-negative
(resting) state that surprisingly consumes a lot of energy to support
communication among neurons. Recent neuroimaging research has also seen an
increase in modeling and analyzing brain activity in terms of a graph or
network. Since graph models facilitate a systems-theoretic explanation of the
brain, they have become increasingly relevant with advances in network science
and the popularization of complex systems theory. The purpose of this study is
to look into the abnormalities in resting brain functions in adults with
Attention Deficit Hyperactivity Disorder (ADHD). The primary goal is to
investigate resting-state functional connectivity (FC), which can be construed
as a significant temporal coincidence in blood-oxygen-level dependent (BOLD)
signals between functionally related brain regions in the absence of any
stimulus or task. When compared to healthy controls, ADHD patients have lower
average connectivity in the Supramarginal Gyrus and Superior Parietal Lobule,
but higher connectivity in the Lateral Occipital Cortex and Inferior Temporal
Gyrus. We also hypothesize that the network organization of default mode and
dorsal attention regions is abnormal in ADHD patients.
