  We present high pressure diamond anvil cell synchrotron X-ray, resistivity,
and ac-susceptibility measurements on electron-doped cuprate
Pr$_{2-x}$Ce$_{x}$CuO$_{4}$ to much higher pressures than previously reported.
At 2.72 GPa between 88 and 98$%$ of the superconducting T$^\prime$ phase
\cite{Tprime} of the optimally doped Pr$_{1.85}$Ce$_{0.15}$CuO$_{4}$ transforms
into the insulating phase T. The T$_{c}$ of the remaining 2-12$%$ T$^\prime$
phase is suppressed continuously from 22 K to 18.5 K at about 14 GPa.
Remarkably, the T$_{c}$ of the over doped Pr$_{1.83}$Ce$_{0.17}$CuO$_{4}$
remains practically unchanged even at 32 GPa. This behavior of the
electron-doped cuprate contrasts with that of the hole-doped cuprate for which
T$_{c}$ is first substantially enhanced with applied pressure.
