  We reanalyze the Fermi-LAT GeV $\gamma$-ray emission in the region of
supernova remnant (SNR) G51.26+0.11 and investigate its interstellar molecular
environment with the CO-line data. At GeV energies, based on 13.2 years of
Fermi-LAT data, the extended $\gamma$-ray emission observed in this region is
resolved into a uniform-disk source ('Src A') with a significance of
19.5$\sigma$ and a point source (4FGL J1924.3+1628) with a significance of
4.2$\sigma$ in 0.2$-$500 GeV. With an angular radius of $\sim$ 0.17$^{\deg}$,
'Src A' overlaps with SNR G51.26+0.11 significantly in the line of sight. On
the other hand, the morphological coincidence between the SNR and the $\sim$
+54 km s$^{-1}$ molecular clouds (MCs) together with the asymmetric or broad
$^{12}$CO line profiles near the SNR boundary provides evidence for the very
likely SNR-MC interaction. The SNR-MC interaction and the HI absorption
features indicate that SNR G51.26+0.11 is located at a kinematic distance of
6.2 $\pm$ 0.5 kpc. Combined with the results from the multi-wavelength
analysis, the $\gamma$-ray emission of the SNR ('Src A') can be naturally
explained by a hadronic model with a soft power-law proton spectrum of index
$\sim$ 2.25.
