  We study the processes
  $e^+e^-\to K^+K^-\pi^0\pi^0\pi^0\gamma$,
  $K^{0}_{S}K^{\pm}\pi^{\mp}\pi^0\pi^0\gamma$, and
$K^{0}_{S}K^{\pm}\pi^{\mp}\pi^+\pi^-\gamma$ in which an energetic photon is
radiated from the initial state. The data were collected with the \babar~
detector at the SLAC National Accelerator Laboratory.
  About 1200, 2600, and 6000 events, respectively, are selected from a data
sample corresponding to an integrated luminosity of 469\invfb. The invariant
mass of the hadronic final state defines the effective \epem center-of-mass
energy. The center-of-mass energies range from threshold to 4.5\gev. From the
mass spectra, the first ever measurements of the $e^+e^-\to
K^+K^-\pi^0\pi^0\pi^0$, $e^+e^-\to K^0_SK^{\pm}\pi^{\mp}\pi^0\pi^0$, and
$e^+e^-\to K^0_SK^{\pm}\pi^{\mp}\pi^+\pi^-$ cross sections are performed. The
contributions from the intermediate states that include $\eta$, $\phi$, $\rho$,
$K^*(892)$, and other resonances are presented. We observe the $J/\psi$ and
$\psi(2S)$ in most of these final states and measure the corresponding
branching fractions, many of them for the first time.
