  Age-related Macular Degeneration (AMD) is a progressive visual impairment
affecting millions of individuals. Since there is no current treatment for the
disease, the only means of improving the lives of individuals suffering from
the disease is via assistive technologies. In this paper we propose a novel and
effective methodology to accurately generate a parametric model for the
perceptual deficit caused by the physiological deterioration of a patient's
retina due to AMD. Based on the parameters of the model, a mechanism is
developed to simulate the patient's perception as a result of the disease. This
simulation can effectively deliver the perceptual impact and its progression to
the patient's eye doctor. In addition, we propose a mixed-reality apparatus and
interface to allow the patient recover functional vision and to compensate for
the perceptual loss caused by the physiological damage. The results obtained by
the proposed approach show the superiority of our framework over the
state-of-the-art low-vision systems.
