  We calculate the contribution of the higher twist Feynman diagrams to the
large-$p_T$ inclusive pion production cross section in proton-proton collisions
in the case of the running and frozen coupling approaches within holographic
QCD. The structure of infrared renormalon singularities of the higher twist
subprocess cross section and it's resummed expression are found. We compare the
resummed higher twist cross sections with the ones obtained in the framework of
the frozen coupling approximation and leading twist cross section. We discuss
the phenomenological consequences of possible higher-twist contributions to the
pion production in proton-proton collisions within holographic QCD.
