  Material surface - analyte interactions play important roles in numerous
processes including gas sensing. However, the effects of topological polar
surface area (TPSA) of analytes on surface interactions during gas sensing have
been so far largely disregarded. In this work, based on experimental
observations on changes in electrical resistance of cadmium sulphide (CdS) due
to surface interactions during gas sensing, we found that unexpected univariate
quadratic correlation exists between changes in resistance of CdS and TPSA of
analytes. Further experiments on four other material systems showed the same
trend, revealing a generalized picture of TPSA dependence of surface
interactions.
