  This Letter presents the first demonstration of multi-tile stitching for
large scale 3D imaging in single objective light-sheet microscopy. We show
undistorted 3D imaging spanning complete zebrafish larvae, and over 1 mm3
volumes for thick mouse brain sections. We use remote galvo scanning for
light-sheet creation and develop a processing pipeline for 3D tiling across
different axes. With the improved one photon (1p) tilt-invariant scanned
oblique plane illumination (SOPi) microscope presented here, we demonstrate
cellular resolution imaging at depths exceeding 330 um in optically scattering
mouse brain samples, and dendritic imaging in more superficial layers.
