  The CLEO collaboration reported observation of the `wrong sign' decay $D^0
\to K^+\pi^-$ in 1993. Upgrades have been made to the CLEO detector, including
installation of a silicon vertex detector, which provide substantial
improvements in sensitivity to $D^0 \to K^+\pi^-$. The vertex detector enables
the reconstruction of the proper lifetime of the $D^0$, and so provides
sensitivity to $D^0-\bar{D}^0$ mixing. We will give preliminary results on the
rate of `wrong sign' decay and $D^0-\bar{D}^0$ mixing using data from the $9.1
fb^{-1}$ of integrated luminosity that has been accumulated with the upgrades
in place. In addition, we will give sensitivity estimates of on-shell
$D^0-\bar{D}^0$ mixing derived from measurement of the lifetime measured with
decays of the $D^0$ to CP eigenstates such as $K^+K^-, \pi^+\pi^-$, and
$K_S\phi$.
