  We discuss equilibration times and isospin effect for various quantities in
low-energy heavy-ion reactions. These include equilibration of mass, isospin,
and total kinetic energy (TKE) in quasifission and deep-inelastic reactions.
The calculations are performed using the time-dependent Hartree-Fock theory.
The influence of shell effects on the equilibration times are also discussed in
the context of theoretical and experimental results.
