  The COVID-19 pandemic has profoundly reshaped our lives, prompting a search
for solutions to its far-reaching effects. Vaccines emerged as a beacon of
hope, yet reaching remote areas faces last-mile hurdles and cost issues due to
loss of vaccine potency due to poor temperature regulation of the storage units
and unanticipated vaccine wastage en route, a common occurrence in conventional
vaccine transportation methods. We introduce ALIVE, a low-cost Interactive
Vaccine Storage Environment module. ALIVE provides an off-grid, self-sufficient
solution for vaccine storage and transport, enabled by active cooling
technology. ALIVE's innovation lies in its integration with the Internet of
Things (IoT), allowing real-time monitoring and control. This IoT-enabled
Application Programming Interface (API) features a data acquisition and
environment parameter control system, managing oversight and decision-making.
ALIVE's compact, lightweight design makes it adaptable to various logistical
scenarios, while its versatility enables it to maintain both time-invariant and
time-dependent thermophysical and spatial parameters. Operationalized through a
PID algorithm, ALIVE ensures precise temperature control within the vaccine
chamber. Its dynamic features, such as remote actuation and data sharing,
demonstrate its adaptability and potential applications. Despite the frugal
nature of development, the system promises significant benefits, including
reduced vaccine loss and remote monitoring advantages. Collaborations with
healthcare partners seek to further enhance ALIVE's readiness and expand its
impact. ALIVE revolutionizes vaccine logistics, offering scalable,
cost-effective solutions for bridging accessibility gaps in challenging
distribution scenarios. Its adaptability positions it for widespread
application, from last-mile vaccine delivery to environment-controlled supply
chains and beyond.
