  There is a very rich literature proposing Bayesian approaches for clustering
starting with a prior probability distribution on partitions. Most approaches
assume exchangeability, leading to simple representations in terms of
Exchangeable Partition Probability Functions (EPPF). Gibbs-type priors
encompass a broad class of such cases, including Dirichlet and Pitman-Yor
processes. Even though there have been some proposals to relax the
exchangeability assumption, allowing covariate-dependence and partial
exchangeability, limited consideration has been given on how to include
concrete prior knowledge on the partition. For example, we are motivated by an
epidemiological application, in which we wish to cluster birth defects into
groups and we have prior knowledge of an initial clustering provided by
experts. As a general approach for including such prior knowledge, we propose a
Centered Partition (CP) process that modifies the EPPF to favor partitions
close to an initial one. Some properties of the CP prior are described, a
general algorithm for posterior computation is developed, and we illustrate the
methodology through simulation examples and an application to the motivating
epidemiology study of birth defects.
