  We model the detailed time-evolution of Discrete Absorption Components (DACs)
observed in P Cygni profiles of the Si IV lam1400 resonance doublet lines of
the fast-rotating supergiant HD 64760 (B0.5 Ib). We adopt the common assumption
that the DACs are caused by Co-rotating Interaction Regions (CIRs) in the
stellar wind. We perform 3D radiative transfer calculations with hydrodynamic
models of the stellar wind that incorporate these large-scale density- and
velocity-structures. We develop the 3D transfer code Wind3D to investigate the
physical properties of CIRs with detailed fits to the DAC shape and morphology.
The CIRs are caused by irregularities on the stellar surface that change the
radiative force in the stellar wind. In our hydrodynamic model we approximate
these irregularities by circular symmetric spots on the stellar surface. We use
the Zeus3D code to model the stellar wind and the CIRs, limited to the
equatorial plane. We constrain the properties of large-scale wind structures
with detailed fits to DACs observed in HD 64760. A model with two spots of
unequal brightness and size on opposite sides of the equator, with opening
angles of 20 +/- 5 degr and 30 +/- 5 degr diameter, and that are 20 +/- 5 % and
8 +/- 5 % brighter than the stellar surface, respectively, provides the best
fit to the observed DACs. The recurrence time of the DACs compared to the
estimated rotational period corresponds to spot velocities that are 5 times
slower than the rotational velocity. The mass-loss rate of the structured wind
model for HD 64760 does not exceed the rate of the spherically symmetric smooth
wind model by more than 1 %. The fact that DACs are observed in a large number
of hot stars constrains the clumping that can be present in their winds, as
substantial amounts of clumping would tend to destroy the CIRs.
