  Comparison of recent experimental STM data with single-impurity and
many-impurity Bogoliubov-de Gennes calculations strongly suggests that random
out-of-plane dopant atoms in cuprates modulate the pair interaction locally.
This type of disorder is crucial to understanding the nanoscale electronic
structure inhomogeneity observed in BSCCO-2212, and can reproduce observed
correlations between the positions of impurity atoms and various aspects of the
local density of states such as the gap magnitude and the height of the
coherence peaks. Our results imply that each dopant atom modulates the pair
interaction on a length scale of order one lattice constant.
