  Light microscopy enables multifunctional imaging of biological specimens at
unprecedented depths and resolutions. However, the performance of all optical
methods degrades with the imaging depth due to sample-induced aberrations.
Methods of adaptive optics (AO) are aimed at pre-compensation of these
distortions but state-of-the-art adaptive optics still provides a limited field
of view and imaging depth. Here I propose a new approach to overcome these
limitations: Fourier image plane conjugate AO. Two possible experimental
designs of the new approach are investigated and an accurate comparison between
proposed and previously used methods of AO is presented. We see that Fourier
conjugate AO provides a significantly larger field of view, which can only be
limited by the angular optical memory effect, as well as it is simpler in
practical realization for large imaging depth and allows the optimal use of
resolution of spatial light modulator.
