  Segmentation of the left atrium and deriving its size can help to predict and
detect various cardiovascular conditions. Automation of this process in 3D
Ultrasound image data is desirable, since manual delineations are
time-consuming, challenging and observer-dependent. Convolutional neural
networks have made improvements in computer vision and in medical image
analysis. They have successfully been applied to segmentation tasks and were
extended to work on volumetric data. In this paper we introduce a combined
deep-learning based approach on volumetric segmentation in Ultrasound
acquisitions with incorporation of prior knowledge about left atrial shape and
imaging device. The results show, that including a shape prior helps the domain
adaptation and the accuracy of segmentation is further increased with
adversarial learning.
