  We explore the skyrmion formation and control possibilities in 2D magnets
from the ubiquitous moir\'e pattern in vdW heterostructures. Using the example
of a ferromagnetic monolayer on an antiferromagnetic substrate, we demonstrate
a new origin of skyrmions in the 2D magnets, from the lateral modulation of
interlayer magnetic coupling by the locally different atomic registries in
moir\'e. The moir\'e skyrmions are doubly degenerate with opposite topological
charge, and trapped at an ordered array of sites with the moir\'e periodicity
that can be dramatically tuned by strain and interlayer translation. At
relatively strong interlayer coupling, the ground states are skyrmion lattices,
where magnetic field can switch the skyrmion vorticity and location in the
moir\'e. At weak interlayer coupling limit, we find metastable skyrmion
excitations on the ferromagnetic ground state that can be deterministically
moved between the ordered moir\'e trapping sites by current pulses. Our results
point to potential uses of moir\'e skyrmions both as information carriers and
as drastically tunable topological background of electron transport.
