  Based on the holographic model, which incorporates the equation of state
(EoS) and baryon number susceptibility for different flavors, we calculate the
drag force, jet quenching parameter, and diffusion coefficient of the heavy
quark at finite temperature and chemical potential. The holographic results for
the diffusion coefficient align with lattice data for $N_f = 0$ and $N_f =
2+1$, falling within their error margins. The holographic diffusion coefficient
for heavy quark in the systems of different flavors agrees with the fitting
results of ALICE data well. The jet quenching parameter in our model
demonstrates strong consistency with the results from both RHIC and LHC for
different flavors. By comparing the experimental data with other models, we can
confirm the validity of our holographic model calculation. The work reinforces
the potential of bottom-up holographic model in advancing our understanding of
transport properties of hot and dense quark-gluon plasma.
