  What level of scientific knowledge has been gained against COVID-19 during
the months of the pandemic? Are current technologies able to keep up with the
advances in virology research? Historically, disease outbreaks due to
pathogenic microorganisms have killed many more people than wars have, and the
ability that viral genes have displayed to rapidly change and adapt has forced
new studies. Early detection is most important for timely management of any
biological attack, whether natural or intentional, and rapid detection systems
are essential to counter the effects of viral disease. Optical sensors have
several advantages in this field, such as simple and label-free protocols. In
this letter, the role of layer materials, such as graphene, is presented.
Graphene has unique and excellent optical properties for plasmonics and Raman
scattering. Finally, a method of Covid-19 detection on graphene sensors is
proposed via a plasmon-molecular orbital interaction that provides a unique
signature of the S-protein of the virus.
