  Context: Regarding the significant interest in both dark matter and the
application of MOND to early-type galaxies, we investigate the MOND theory by
comparing its predictions, for models of constant mass-to-light ratio, with
observational data of the early-type galaxy NGC 4649.
  Aims: We study whether measurements for NGC 3379 and NGC 1399 are typical of
early-type systems and we test the assumption of a Newtonian constant M/L ratio
underlying most of the published models.
  Methods: We employ the globular clusters of NGC 4649 as a mass tracer. The
Jeans equation is calculated for both MOND and constant mass-to-light ratio
assumptions. Spherical symmetry is assumed and the calculations are performed
for both isotropic and anisotropic cases.
  Results: We found that both Jeans models with the assumption of a constant
mass-to-light ratio and different MOND models provide good agreement with the
observed values of the velocity dispersion. The most accurate fits of the
velocity dispersion were obtained for the mass-to-light ratio in the B-band,
which was equal to 7, implying that there is no need for significant amounts of
dark matter in the outer parts (beyond 3 effective radii) of this galaxy. We
also found that tangential anisotropies are most likely present in NGC 4649.
