  Competition within the immune system may degrade immune control of viral
infections. We formalize the evolution that occurs in both HIV-1 and the immune
system quasispecies. Inclusion of competition in the immune system leads to a
novel balance between the immune response and HIV-1, in which the eventual
outcome is HIV-1 escape rather than control. The analytical model reproduces
the three stages of HIV-1 infection. We propose a vaccine regimen that may be
able to reduce competition between T cells, potentially eliminating the third
stage of HIV-1.
