  Reproducible document standards, like R Markdown, facilitate the programmatic
creation of documents whose content is itself programmatically generated. While
these documents are generally not complete in the sense that they will not
include prose content, generated by an author to provide context, a narrative,
etc., programmatic generation can provide substantial efficiencies for
structuring and constructing documents. This paper explores the programmatic
generation of reproducible by distinguishing components than can be created by
computational means from those requiring human-generated prose, providing
guidelines for the generation of these documents, and identifying a use case in
clinical trial reporting. These concepts and use case are illustrated through
the listdown package for the R programming environment, which is is currently
available on the Comprehensive R Archive Network (CRAN).
