  In this work, multiplicities of zeros of skew polynomials are studied. Two
distinct definitions are considered: First, $ a $ is said to be a zero of $ F $
of multiplicity $ r $ if $ (x-a)^r $ divides $ F $ on the right; second, $ a $
is said to be a zero of $ F $ of multiplicity $ r $ if some skew polynomial $ P
= (x-a_r) \cdots (x-a_2) (x-a_1) $, having $ a_1 = a $ as its only right zero,
divides $ F $ on the right. Neither of these two notions implies the other for
general skew polynomials. We show that, in the first case, Lam and Leroy's
concept of P-independence does not behave naturally, whereas a union theorem
still holds. In contrast, we show that P-independence behaves naturally for the
second notion of multiplicities. As a consequence, we provide extensions of
classical commutative results to general skew polynomials. These include: (1)
The upper bound on the number of (P-independent) zeros (counting
multiplicities) of a skew polynomial by its degree, and (2) The equivalence of
P-independence, Hermite interpolation and the invertibility of confluent
Vandermonde matrices (for which we introduce skew polynomial Hasse
derivatives).
