  Significant fraction (about 98.5% in humans, 24% in microbe Rickettsia
prowazekii) of most animal genomes is non-coding DNA. Although recent studies
established functions of its certain portions, it remains genomic dark matter.
The paper unravels its unusual nature with time reversal approach. Any genome
emerged in evolutionary selection of the fittest survivors. Survivability of
modern species is extensively quantified. Accurate analysis establishes that
under specified conditions it is dominated by the same law in species from
human to single-cell yeast. Since all violators of the law perished in the
previous evolution, it presents the exact law of unanticipated universal
(rather than species specific natural) evolutionary selection of survivors. The
law implies their rapid hereditary, thus genetic, adaptation which is navigated
by operating system of non-coding DNA. Such adaptation to drastic environmental
changes was a must for survival, thus evolved, in otherwise lethal major mass
extinctions. Navigator genome allows for rapid, artificial included, biological
changes (e.g., Methuselah lifespan). Universal law establishes biological
relativity to age transformation in any species; quantifies applicability of
animal models to humans; implies certain universality in biological complexity
and reduces it to exact science problem. Evolutionary and experimental data
corroborate all above conclusions. Further theoretical study and test-stone
experiments are suggested.
