  A simple model for the formation of the polymer-enzyme conjugates has been
proposed and described using corresponding extension of the Wertheim's
first-order thermodynamic perturbation theory (TPT1) for the system of
associating chain molecules. A set of computer simulation data for different
number of functional groups along polymer chains has been obtained and used to
access the accuracy of the theoretical results. Predictions of the present
theoretical approach are more accurate than that of the conventional TPT1 and
are in a very good agreement with the computer simulation data. In particular
the theory is able to account for the difference in position of the polymer
functional groups along its backbone.
