  We describe a statistical model to estimate the covariance matrix of matter
tracer two-point correlation functions with cosmological simulations. Assuming
a fixed number of cosmological simulation runs, we describe how to build a
`statistical emulator' of the two-point function covariance over a specified
range of input cosmological parameters. Because the simulation runs with
different cosmological models help to constrain the form of the covariance, we
predict that the cosmology-dependent covariance may be estimated with a
comparable number of simulations as would be needed to estimate the covariance
for fixed cosmology. Our framework is a necessary first step in planning a
simulations campaign for analyzing the next generation of cosmological surveys.
