  We employ a multiscale approach to model the translocation of biopolymers
through nanometer size pores. Our computational scheme combines microscopic
Langevin molecular dynamics (MD) with a mesoscopic lattice Boltzmann (LB)
method for the solvent dynamics, explicitly taking into account the
interactions of the molecule with the surrounding fluid. Both dynamical and
statistical aspects of the translocation process were investigated, by
simulating polymers of various initial configurations and lengths. For a
representative molecule size, we explore the effects of important parameters
that enter in the simulation, paying particular attention to the strength of
the molecule-solvent coupling and of the external electric field which drives
the translocation process. Finally, we explore the connection between the
generic polymers modeled in the simulation and DNA, for which interesting
recent experimental results are available.
