  An interesting class of molecules is that in which the molecules do not
possess a stereogenic center but can become chiral due to their spatial
arrangement. These molecules can be seen as chiral conformers, whose two
non-superimposable forms can interconvert from one another by rotations about
single bonds. Here, we show that an initially racemic mixture of chiral
conformers, such as a sample of cyclohexylmethanol, C$_{7}$H$_{14}$O (CHM), can
be enantiomerically enriched by performing the enantio-selective process of
coherent population transfer between rotational levels. By first performing a
population transfer cycle, followed by a three-wave mixing experiment, we show
that an enantiomeric excess in a rotational level of choice can be achieved.
This represents the first experimental demonstration of such an effect in a
chiral pair of conformers, and it showcases the broad applicability of
three-wave mixing not only for analytical applications but also to a wide scope
of experiments of fundamental interest.
