  Efforts to map atomic-scale chemistry at low doses with minimal noise using
electron microscopes are fundamentally limited by inelastic interactions. Here,
fused multi-modal electron microscopy offers high signal-to-noise ratio (SNR)
recovery of material chemistry at nano- and atomic- resolution by coupling
correlated information encoded within both elastic scattering (high-angle
annular dark field (HAADF)) and inelastic spectroscopic signals (electron
energy loss (EELS) or energy-dispersive x-ray (EDX)). By linking these
simultaneously acquired signals, or modalities, the chemical distribution
within nanomaterials can be imaged at significantly lower doses with existing
detector hardware. In many cases, the dose requirements can be reduced by over
one order of magnitude. This high SNR recovery of chemistry is tested against
simulated and experimental atomic resolution data of heterogeneous
nanomaterials.
