  We present algorithm MIQCR-CB that is an advancement of method
MIQCR~(Billionnet, Elloumi and Lambert, 2012). MIQCR is a method for solving
mixed-integer quadratic programs and works in two phases: the first phase
determines an equivalent quadratic formulation with a convex objective function
by solving a semidefinite problem $(SDP)$, and, in the second phase, the
equivalent formulation is solved by a standard solver. As the reformulation
relies on the solution of a large-scale semidefinite program, it is not
tractable by existing semidefinite solvers, already for medium sized problems.
To surmount this difficulty, we present in MIQCR-CB a subgradient algorithm
within a Lagrangian duality framework for solving $(SDP)$ that substantially
speeds up the first phase. Moreover, this algorithm leads to a reformulated
problem of smaller size than the one obtained by the original MIQCR method
which results in a shorter time for solving the second phase.
  We present extensive computational results to show the efficiency of our
algorithm.
