  We present a {\em Spitzer}-based mid-infrared study of a large sample of Blue
Compact Dwarf galaxies (BCD) using the Infrared Spectrograph (IRS), including
the first mid-IR spectrum of IZw18, the archetype for the BCD class and among
the most metal poor galaxies known. We show the spectra of Polycyclic Aromatic
Hydrocarbon (PAH) emission in low-metallicity environment. We find that the
equivalent widths (EW) of PAHs at 6.2, 7.7, 8.6 and 11.2 $\mu$m are generally
weaker in BCDs than in typical starburst galaxies and that the fine structure
line ratio, [NeIII]/[NeII], has a weak anti-correlation with the PAH EW. A much
stronger anti-correlation is shown between the PAH EW and the product of the
[NeIII]/[NeII] ratio and the UV luminosity density divided by the metallicity.
We conclude that PAH EW in metal-poor high-excitation environments is
determined by a combination of PAH formation and destruction effects.
