  The present paper investigates the extension behavior of a wormlike chain
with varied persistence length under the confinement of a cylindrical tube.
Based on Odijk theory of a confined polymer chain, we have developed a theory
which can describe the mechanical behavior of wormlike chain with varying
bending rigidities along the chain. In order to validate our model, we also
performed large numbers of Brownian dynamics simulations based on the
generalized bead model (GBR), which illustrate that our theory is in good
agreement with simulation results.
