  In an attempt to remove the systematic errors which have plagued the
calibration of the HII region abundance sequence, we have theoretically modeled
the extragalactic HII region sequence. We then used the theoretical spectra so
generated in a double blind experiment to recover the chemical abundances using
both the classical electron temperature + ionization correction factor
technique, and the technique which depends on the use of strong emission lines
(SELs) in the nebular spectrum to estimate the abundance of oxygen. We find a
number of systematic trends, and we provide correction formulae which should
remove systematic errors in the electron temperature + ionization correction
factor technique. We also provide a critical evaluation of the various
semi-empirical SEL techniques. Finally, we offer a scheme which should help to
eliminate systematic errors in the SEL-derived chemical abundance scale for
extragalactic HII regions.
