  The ribosome is a macromolecular complex which is responsible for protein
synthesis in all living cells according to their transcribed genetic
information. Using X-ray crystallography and, more recently, cryo-electron
microscopy (cryo-EM), the structure of the ribosome was resolved at atomic
resolution in many functional and conformational states. Molecular dynamics
simulations have added information on dynamics and energetics to the available
structural information, thereby have bridged the gap to the kinetics obtained
from single-molecule and bulk experiments. Here, we review recent computational
studies that brought notable insights into ribosomal structure and function.
