  We present a single-electron device for the manipulation of charge states via
quantum interference in nanostructured electrodes. Via self-inductance effects,
we induce two independent magnetic fluxes in the electrodes and we demonstrate
sensitivity to single charge states and magnetic field at variable temperature.
Moreover, our approach allows us to demonstrate local and independent control
of the single-particle conductance between nano-engineered tunnel junctions in
a fully-Superconducting Quantum Interference Single-Electron Transistor
(SQUISET), thereby increasing the flexibility of our single-electron
transistors. Our devices show a robust modulation of the current-to-flux
transfer function via control currents, while exploiting the single-electron
filling of a mesoscopic superconducting island. Further applications of the
device concept to single-charge manipulation and magnetic-flux sensing are also
discussed.
