  The principle of maximum conformality (PMC) is used to remove uncertainties
from the renormalization scale and the renormalization scheme, removing
unnecessary systematic errors for high-precision pQCD predictions. In this
paper, we will use PMC to improve the determination of the decay width of the W
boson in hadrons, working the corrections coming from the perturbative Quantum
Chromodynamics (pQCD) theory at the four-loop level. In conventional scaling,
we find that only at high correction orders, the initial scaling dependence of
renormalization is little, whereas, in single-scale PMC, we obtain an initial
scaling-independent result, including the case determined via BLM/ PMC.
Finally, the wide hadronic decay of W is used for an indirect determination of
the the charm-strange mixing parameter.
