  Generalizing self-duality on R^2 x S^2 to higher dimensions, we consider the
Donaldson-Uhlenbeck-Yau equations on R^{2n} x S^2 and their noncommutative
deformation for the gauge group U(2). Imposing SO(3) invariance (up to gauge
transformations) reduces these equations to vortex-type equations for an
abelian gauge field and a complex scalar on R^{2n}_\theta. For a special
S^2-radius R depending on the noncommutativity \theta we find explicit
solutions in terms of shift operators. These vortex-like configurations on
R^{2n}_\theta determine SO(3)-invariant multi-instantons on R^{2n}_\theta x
S^2_R for R=R(\theta). The latter may be interpreted as sub-branes of
codimension 2n inside a coincident pair of noncommutative Dp-branes with an S^2
factor of suitable size.
