  The universe is a vast heterogeneous network of interconnected entities that
continuously generate and exchange information through various forms of
interactions, some of which are yet to be discovered. Internet of Everything
(IoE) framework, inspired by the ubiquitous and adaptive connectivity and the
seamless interoperability within this universal network, puts forward a new
road map beyond the conventional Internet of Things (IoT) towards maximizing
the resolution of our interface with the universe to enable unprecedented
applications. The first pillar of this road map is to reveal novel and tangible
interconnections between seemingly noninteracting branches of IoT, which we
call IoXs with X referring to their application domains, e.g., Internet of
Energy (IoEn), Internet of Vehicles (IoV). The second pillar is to develop new
IoXs that can complement the existing ones to complete the overall IoE picture
and match its networking traits to that of the universe for a seamless and
all-embracing cyber-physical interface. The objective of this paper is to
evaluate the potential of this holistic IoE approach to expand the limited
application landscape of the current IoT practice on a scale ranging
$\textit{from molecules to the universe}$. To this end, we identify several
potential interaction pathways among IoXs and introduce novel and emerging IoXs
that are essential to the comprehensiveness of IoE. We also discuss the
potential applications that can be enabled by such interconnections within the
IoE framework and identify the associated challenges.
