  The spatial arrangement of galaxies (of satellites on a scale of 100kpc) as
well as their three-dimensional distribution in galaxy groups such as the Local
Group (on a scale of 1Mpc), the distribution of galaxies in the nearby volume
of galaxies (on a scale of 8Mpc) and in the nearby Universe (on a scale of
1Gpc) is considered. There is further evidence that the CMB shows
irregularities and for anisotropic cosmic expansion. The overall impression one
obtains, given the best data we have, is matter to be arranged as not expected
in the dark-matter based standard model of cosmology (SMoC). There appears to
be too much structure, regularity and organisation. Dynamical friction on the
dark matter halos is a strong direct test for the presence of dark matter
particles, but this process does not appear to be operative in the real
Universe. This evidence suggests strongly that dynamically relevant dark matter
does not exist and therefore cosmology remains largely not understood
theoretically. More-accepted awareness of this case would by itself constitute
a major advance in research providing fabulous opportunities for bright minds,
and the observational data strongly suggest that gravitation must be
effectively Milgromian, corresponding to a generalized Poisson equation in the
classical limit. Thus, physical cosmology offers a significant historically
relevant opportunity for ground-breaking work, at least for those daring to do
so.
