  The first observations of deuterium and oxygen in the Local Interstellar
Medium (LISM) obtained with the Far Ultraviolet Spectroscopic Explorer (FUSE)
can be used to search for local abundance variations. While the very limited
sample of these first data may be consistent with no variations, they do offer
a hint of anti-correlated variations between D/H and O/H. If confirmed by more
data (which will require independently determined, accurate HI column
densities), these hints suggest that observations of interstellar gas within a
few kpc of the solar neighborhood will reveal clear signs of the evolution of
the abundance of deuterium from there and then (the Big Bang), to here and now
(the Local Interstellar Medium of the Galaxy).
