  Quantum techniques can be used to enhance the signal-to-noise ratio in
optical imaging. Leveraging the latest advances in single photon avalanche
diode array cameras and multi-photon detection techniques, here we introduce a
super-sensitive phase imager, which uses space-polarization hyper-entanglement
to operate over a large field-of-view without the need of scanning operation.
We show quantum-enhanced imaging of birefringent and non-birefringent phase
samples over large areas, with sensitivity improvements over equivalent
classical measurements carried out with equal number of photons. The practical
applicability is demonstrated by imaging a biomedical protein microarray
sample. Our quantum-enhanced phase imaging technology is inherently scalable to
high resolution images, and represents an essential step towards practical
quantum imaging.
