  The major histocompatibility complex (MHC) molecules, which bind peptides for
presentation on the cell surface, play an important role in cell-mediated
immunity. In light of developing databases and technologies over the years,
significant progress has been made in research on peptide binding affinity
calculation. Several in techniques have been developed to predict peptide
binding to MHC class I. Most of the research on MHC Class I due to its nature
brings better performance and more. Considering the use of different methods
and different technologies, and the approach of similar methods on different
proteins, a classification was created according to the binding affinity of
protein peptides.
