  Architected materials can achieve enhanced properties compared to their plain
counterparts. Specific architecting serves as a powerful design lever to
achieve targeted behavior without changing the base material. Thus, the
connection between architected structure and resultant properties remains an
open field of great interest to many fields, from aerospace to civil to
automotive applications. Here, we focus on properties related to mechanical
compression, and design hierarchical honeycomb structures to meet specific
values of stiffness and compressive stress. To do so, we employ a combination
of techniques in a singular workflow, starting with molecular dynamics
simulation of the forward design problem, augmenting with data-driven
artificial intelligence models to address the inverse design problem, and
verifying the behavior of de novo structures with experimentation of additively
manufactured samples. We thereby demonstrate an approach for architected design
that is generalizable to multiple material properties and agnostic to the
identity of the base material.
