  It is shown how to take advantage of the frequent occurrence of double-strand
breaks in the genome of prokaryotic cells, in order to reduce their high
efficient reproductive capability. The analysis examines the physical status of
the free ends of each break and considers how this status can interfere with an
external physical apparatus, with the aim of undermining the repair processes.
We indicate the biological consequences of this interaction and we give an
approximate evaluation of the topological and dynamical effects that arise on
the genomic material involved. The overall result suggests a significant
reduction of the dynamics of the repair.
