  Magnetic resonance image (MRI) reconstruction is a severely ill-posed linear
inverse task demanding time and resource intensive computations that can
substantially trade off {\it accuracy} for {\it speed} in real-time imaging. In
addition, state-of-the-art compressed sensing (CS) analytics are not cognizant
of the image {\it diagnostic quality}. To cope with these challenges we put
forth a novel CS framework that permeates benefits from generative adversarial
networks (GAN) to train a (low-dimensional) manifold of diagnostic-quality MR
images from historical patients. Leveraging a mixture of least-squares (LS)
GANs and pixel-wise $\ell_1$ cost, a deep residual network with skip
connections is trained as the generator that learns to remove the {\it
aliasing} artifacts by projecting onto the manifold. LSGAN learns the texture
details, while $\ell_1$ controls the high-frequency noise. A multilayer
convolutional neural network is then jointly trained based on diagnostic
quality images to discriminate the projection quality. The test phase performs
feed-forward propagation over the generator network that demands a very low
computational overhead. Extensive evaluations are performed on a large
contrast-enhanced MR dataset of pediatric patients. In particular, images rated
based on expert radiologists corroborate that GANCS retrieves high contrast
images with detailed texture relative to conventional CS, and pixel-wise
schemes. In addition, it offers reconstruction under a few milliseconds, two
orders of magnitude faster than state-of-the-art CS-MRI schemes.
