  ISAJET is a Monte Carlo program which simulates $pp$, $\bar pp$ and $e^+e^-$
interactions at high energies. This document summarizes the physics underlying
the program and describes how to use it. Version~7.48 includes several new
features. Anomaly Mediated SUSY Breaking (AMSB) models and right-handed
sneutrinos have been added; the latter play a role, e.g., in inverted hierarchy
models. A new process generating $Z+\hbox{2 jets}$ based on the Helas library
and MadGraph has been added. Another new process generating Kaluza-Klein
gravitons in models with extra dimensions has been added.
