  We study the consistency and consistency strength of various configurations
concerning the cardinal characteristics
$\mathfrak{s}_\theta,\mathfrak{p}_\theta,\mathfrak{g}_\theta,\mathfrak{r}_\theta,\mathfrak{t}_\theta$
at uncountable regular cardinals $\theta$. Motivated by a theorem of
Raghavan-Shelah who proved that $\mathfrak{s}_\theta\leq\mathfrak{b}_\theta$,
we explore in the first part of the paper the consistency of inequalities
comparing $\mathfrak{s}_\theta$ with $\mathfrak{p}_\theta$ and
$\mathfrak{g}_\theta$. In the second part of the paper we study variations of
the extender-based Radin forcing to establish several consistency results
concerning $\mathfrak{r}_\theta$ from hyper-measurability assumptions, results
which were previously known to be consistent only from supercompactness
assumptions. In doing so, we answer several questions which appeared in the
literature.
