  We investigate the voltage-driven transport of hybridized DNA through
membrane channels. As membrane channels are typically too narrow to accommodate
hybridized DNA, the dehybridization of the DNA is the critical rate limiting
step in the transport process. Using a two-dimensional stochastic model, we
show that the dehybridization process proceeds by two distinct mechanisms;
thermal denaturation in the limit of low driving voltage, and direct stripping
in the high to moderate voltage regime. Additionally, we investigate the
effects of introducing non-homologous defects into the DNA strand.
