  Different graphical plots involving the catalytic rate with the (initial)
substrate concentration exist in the enzyme kinetics literature to estimate the
reaction constants. But, none of these standard plots can unambiguously
distinguish between the two important mechanisms of rate enhancement: positive
cooperativity among the active sites of an oligomeric enzyme and auto-catalysis
of the intermediate complex of an enzyme with a single active site. We achieve
this distinction here by providing a nice linear plot for the latter.
Importantly, to accomplish this task, no extra information other than the
steady-state rate as a function of substrate concentration is required.
