  We investigate the microtubule polymerization dynamics with catastrophe and
rescue events for three different confinement scenarios, which mimic typical
cellular environments: (i) The microtubule is confined by rigid and fixed
walls, (ii) it grows under constant force, and (iii) it grows against an
elastic obstacle with a linearly increasing force. We use realistic catastrophe
models and analyze the microtubule dynamics, the resulting microtubule length
distributions, and force generation by stochastic and mean field calculations;
in addition, we perform stochastic simulations. We also investigate the force
dynamics if growth parameters are perturbed in dilution experiments. Finally,
we show the robustness of our results against changes of catastrophe models and
load distribution factors.
