  In this thesis we investigate two different sets of physics questions, aiming
at a better understanding of the low-energy behaviour of Yang-Mills theories,
and the properties connected to confinement, in a first part. In a second part,
we consider asymptotically safe quantum gravity, which is a proposal for a UV
completion of gravity, based on the existence of an interacting UV fixed point
in the Renormalisation Group flow. Both theories are characterised by
non-perturbative behaviour, the first in the IR, the second in the UV, thus we
apply a functional Renormalisation Group equation which is valid beyond the
perturbative regime. We investigate the ground state of SU(3) Yang-Mills
theory, finding the formation of a gluon condensate, which we connect to a
model for quark confinement. We further investigate the deconfinement phase
transition at finite temperature for several gauge groups and shed light on the
question what determines the order of the phase transition. Within quantum
gravity, we examine the properties of the Faddeev-Popov ghost sector in a
non-perturbative regime, thus extending truncations of Renormalisation Group
flows into a new set of directions in theory space. Finally we establish a
connection of quantum gravity to observations of matter, by coupling fermions
to gravity. Here we use the existence of light fermions - an observationally
well-established fact in our universe - to impose constraints on quantum
theories of gravity.
