  This paper demonstrates an on-chip anhydrous D-glucose sensor based using a
coplanar stripline (CPS) on a thin (1 um) silicon nitride membrane at terahertz
(THz) frequencies. A thin layer (~10 um) of D-glucose was placed in close
proximity to the CPS and the transmission response was measured using a
modified THz-TDS setup. The D-glucose introduces frequency-dependent changes to
the effective permittivity of the CPS resulting in a modified spectral response
at the receiver. Measurement results show absorption signatures at 1.42 THz and
2.07 THz corresponding to the first two significant resonances beyond 1 THz for
D-glucose allowing for label-free detection. The frequency-dependent
attenuation coefficient was estimated by simulation for several D-glucose layer
thicknesses using a modified Lorentz model. Measurement results align with
simulations and other literature that use free-space THz radiation. This work
verifies on-chip THz sensing of D-glucose and presents a pathway towards
on-chip sensing of other materials at THz frequencies.
