  We apply new upper limits on neutrino fluxes and the diffuse extragalactic
component of the GeV gamma-ray flux to various scenarios for ultra high energy
cosmic rays and neutrinos. As a result we find that extra-galactic top-down
sources can not contribute significantly to the observed flux of highest energy
cosmic rays. The Z-burst mechanism where ultra-high energy neutrinos produce
cosmic rays via interactions with relic neutrinos is practically ruled out if
cosmological limits on neutrino mass and clustering apply.
