  Machine Learning may push research in precision medicine to unprecedented
heights. To succeed, machine learning needs a large amount of data, often
including personal data. Therefore, machine learning applied to precision
medicine is on a cliff edge: if it does not learn to fly, it will deeply fall
down. In this paper, we present Active Informed Consent (AIC) as a novel hybrid
legal-technological tool to foster the gathering of a large amount of data for
machine learning. We carefully analyzed the compliance of this technological
tool to the legal intricacies protecting the privacy of European Citizens.
