  Emergence and maintenance of polymers with complex sequences is a major
question in the study of origins of life. To answer this, we studied a model
polymerization reaction, where polymers are synthesized by stepwise ligation
from two types of monomers, catalyzed by a long polymer as a template. Direct
stochastic simulation and dynamical systems analysis revealed that the most
dominant polymer sequence in a population successively changes against the flow
rate of monomer to the system. The slower the flow, the more is the complex
sequence selected. We discuss the relevance of this kinetic selection of
sequence by the non-equilibrium flow rate to the origin of complex polymers.
