  Living organisms are primarily made of cells. Identifying them and
characterizing their geometry and spatial distribution is a first step towards
building multi-scale models of these biomaterials. We propose a method to count
cells using nuclei in an X-ray microtomographic scan of a zebrafish. To account
for scanning artifacts and partial volume effect, the method is adaptively
calibrated using parameters approximated from the manifold of manually selected
and optimized special cases. The methodology is tested on nuclei in the eyes of
zebrafish larvae of different ages.
