  We review the present status of Cosmic Microwave Background (CMB) anisotropy
observations and discuss the main related astrophysical issues, instrumental
effects and data analysis techniques. We summarise the balloon-borne and
ground-based experiments that, after COBE-DMR, yielded detection or significant
upper limits to CMB fluctuations. A comparison of subsets of combined data
indicates that the acoustic features observed today in the angular power
spectrum are not dominated by undetected systematics. Pushing the accuracy of
CMB anisotropy measurements to their ultimate limits represents one of the best
opportunities for cosmology to develop into a precision science in the next
decade. We discuss the forthcoming sub-orbital and space programs, as well as
future prospects of CMB observations.
