  Asymmetries in the distribution of light and neutral hydrogen are often
observed in spiral galaxies. Here, attention is drawn to the presence of
large-scale asymmetries in their kinematics. Two examples of kinematically
lopsided galaxies are presented and discussed. The shape of the rotation curve
--rising more steeply on one side of the galaxy than on the other-- is the
signature of the kinematic lopsidedness. It is shown that kinematic
lopsidedness may be related to lopsidedness in the potential, and that even a
mild perturbation in the latter can produce significant kinematical effects.
Probably at least half of all spiral galaxies are lopsided.
