  This work is aimed at studying the influence of critical Casimir effects on
energetic properties of curved defect lines in the frame of 2D Ising model. Two
types of defect curves were investigated. We start with a simple task of
globule formation from four-defect line. It was proved that an exothermic
reaction of collapse occurs and the dependence of energy release on temperature
was observed. Critical Casimir energy of extensive line of constant curvature
was also examined. It was shown that its critical Casimir energy is
proportional to curvature that leads to the tendency to radius decreasing under
Casimir forces. The results obtained can be applied to proteins folding problem
in polarized liquid.
