  In many-body nonlinear systems with sufficient anharmonicity, a special kind
of lattice vibrations, namely, Localized Anharmonic Vibrations (LAVs) can be
excited either thermally or by external triggering, in which the amplitude of
atomic oscillations greatly exceeds that of harmonic oscillations (phonons)
that determine the system temperature. Coherency and persistence of LAVs may
have drastic effect on quantum tunneling due to correlation effects discovered
by Schrodinger and Robertson in 1930. These effects have been applied to the
tunneling problem by a number of authors, who demonstrated a giant increase of
sub-barrier transparency during the increase of the correlation coefficient at
a special high-frequency periodic action on quantum system. Recently, it has
been proposed that discrete breathers (a sub-class of LAVs arising in periodic
systems) present the most natural and efficient way to produce correlation
effects in regular crystals due to time-periodic modulation of the potential
well (or the Coulomb barrier) width and hence to act as breather nano-colliders
catalyzing low energy nuclear reactions (LENR) in solids. It has been shown
that the tunneling probability for the D-D fusion under electrolysis of heavy
water increases enormously with increasing number of oscillations resulting in
the fusion rates comparable with those observed experimentally. In the present
paper, we discuss possible ways of engineering the nuclear-active environment
(NAE) and catalyzing LENR in NAE based on the LAV concept. We propose some
practical ways of catalyzing LENR that are based on a special electro-magnetic
treatment or electron irradiation, which trigger LAVs in crystals and clusters.
