  In the first part of this talk it is discussed why observed neutrino
oscillations (which suggest the existence of right-handed neutrinos with
certain Dirac and Majorana masses) seem to select out the route to higher
unification based on the symmetry SU(4)-color. This in turn selects out the
effective symmetry in 4D near the GUT/string scale to be either SO(10) or
minimally G(224)= SU(2)_L\times SU(2)_R \times SU(4)^c. The same conclusion is
reached by the likely need for leptogenesis as the means for baryogenesis and
also by the success of certain fermion mass-relations including
m_b(M_{GUT})\approx m_\tau, together with m(\nu^\tau)_{Dirac}\approx
m_{top}(M_{GUT}). In the second part, an attempt is made to provide a unified
picture of a set of diverse phenomena based on an effective G(224) symmetry or
SO(10), possessing supersymmetry. The phenomena in question include: (a)
fermion masses and mixings, (b) neutrino oscillations, (c) CP non-conservation,
(d) flavor violations in quark and lepton sectors, as well as (e) baryogenesis
via leptogenesis. Including SM and SUSY contributions, the latter being
sub-dominant, the framework correctly accounts for \Delta m_K, \Delta m_{B_d},
  S(B_d -> J/\psi K_s) and \epsilon_K, and predicts S(B_d-> \phi K_s) to be in
the range +(0.65-0.73), close to the SM-prediction. It also quite plausibly
accounts for the observed baryon excess Y_B\approx 10^{-10}. Furthermore the
model predicts enhanced rates for mu -> e gamma, tau-> mu gamma and mu N-> e N
and also measurable electric dipole moment for the neutron. Expectations
arising within the same framework for proton decay are summarized at the end.
It is stressed that the potential for discovering proton decay in a
megaton-size detector would be high.
