  We study the mixed effect of QCD and QED corrections to the evolution of
parton distribution functions (PDFs). The Altarelli-Parisi splitting functions
are extended to one order higher in QED, reaching ${\cal O}(\alpha \,
\alpha_S^2)$ accuracy. This also involves extending DGLAP equations to include
charge separation effects, that are ignored for pure QCD corrections. Besides
that, these effects are crucial for the determination of the photon
distribution, which plays an increasingly important role in nowadays
phenomenological analysis.
