  Integrated Computational Materials Engineering (ICME) calls for the
integration of computational tools into the materials and parts development
cycle, while the Materials Genome Initiative (MGI) calls for the acceleration
of the materials development cycle through the combination of experiments,
simulation, and data. As they stand, both ICME and MGI do not prescribe how to
achieve the necessary tool integration or how to efficiently exploit the
computational tools, in combination with experiments, to accelerate the
development of new materials and materials systems. This paper addresses the
first issue by putting forward a framework for the fusion of information that
exploits correlations among sources/models and between the sources and `ground
truth'. The second issue is addressed through a multi-information source
optimization framework that identifies, given current knowledge, the next best
information source to query and where in the input space to query it via a
novel value-gradient policy. The querying decision takes into account the
ability to learn correlations between information sources, the resource cost of
querying an information source, and what a query is expected to provide in
terms of improvement over the current state. The framework is demonstrated on
the optimization of a dual-phase steel to maximize its strength-normalized
strain hardening rate. The ground truth is represented by a
microstructure-based finite element model while three low fidelity information
sources---i.e. reduced order models---based on different homogenization
assumptions---isostrain, isostress and isowork---are used to efficiently and
optimally query the materials design space.
