  There are 8000 galaxies, including 1600 at z larger than 1.6, which could be
simultaneously observed in an E-ELT field of view of 40 sq. arcmin. A
considerable fraction of astrophysical discoveries require large statistical
samples, which can only be obtained with multi-object spectrographs (MOS).
MOSAIC will provide a vast discovery space, enabled by a multiplex of 200 and
spectral resolving powers of R=5000 and 20000. MOSAIC will also offer the
unique capability of more than 10 "high-definition" (multi-object adaptive
optics, MOAO) integral-field units, optimised to investigate the physics of the
sources of reionization. The combination of these modes will make MOSAIC the
world-leading MOS facility, contributing to all fields of contemporary
astronomy, from extra-solar planets, to the study of the halo of the Milky Way
and its satellites, and from resolved stellar populations in nearby galaxies
out to observations of the earliest "first-light" structures in the Universe.
It will also study the distribution of the dark and ordinary matter at all
scales and epochs of the Universe. Recent studies of critical technical issues
such as sky-background subtraction and MOAO have demonstrated that such a MOS
is feasible with state-of-the-art technology and techniques. Current studies of
the MOSAIC team include further trade-offs on the wavelength coverage, a
solution for compensating for the non-telecentric new design of the telescope,
and tests of the saturation of skylines especially in the near-IR bands. In the
2020s the E-ELT will become the world's largest optical/IR telescope, and we
argue that it has to be equipped as soon as possible with a MOS to provide the
most efficient, and likely the best way to follow-up on James Webb Space
Telescope (JWST) observations.
