  The BraTS 2021 challenge celebrates its 10th anniversary and is jointly
organized by the Radiological Society of North America (RSNA), the American
Society of Neuroradiology (ASNR), and the Medical Image Computing and Computer
Assisted Interventions (MICCAI) society. Since its inception, BraTS has been
focusing on being a common benchmarking venue for brain glioma segmentation
algorithms, with well-curated multi-institutional multi-parametric magnetic
resonance imaging (mpMRI) data. Gliomas are the most common primary
malignancies of the central nervous system, with varying degrees of
aggressiveness and prognosis. The RSNA-ASNR-MICCAI BraTS 2021 challenge targets
the evaluation of computational algorithms assessing the same tumor
compartmentalization, as well as the underlying tumor's molecular
characterization, in pre-operative baseline mpMRI data from 2,040 patients.
Specifically, the two tasks that BraTS 2021 focuses on are: a) the segmentation
of the histologically distinct brain tumor sub-regions, and b) the
classification of the tumor's O[6]-methylguanine-DNA methyltransferase (MGMT)
promoter methylation status. The performance evaluation of all participating
algorithms in BraTS 2021 will be conducted through the Sage Bionetworks Synapse
platform (Task 1) and Kaggle (Task 2), concluding in distributing to the top
ranked participants monetary awards of $60,000 collectively.
