  Optically thin accretion plasmas can reach ion temperatures $T_{\rm i} \geq
10^{10}$K and thus trigger nuclear reactions. Using a large nuclear
interactions network, we studied the radial evolution of the chemical
composition of the accretion flow toward the black hole and computed the
emissivity in nuclear $\gamma$-ray lines. In the advection dominated accretion
flow (ADAF) regime, CNO and heavier nuclei are destroyed before reaching the
last stable orbit. The overall luminosity in the de-excitation lines for a
solar composition of plasma can be as high as few times $10^{-5}$ the accretion
luminosity ($\dot{M}c^2$) and can be increased for heavier compositions up to
$10^{-3}$. The efficiency of transformation of the kinetic energy of the
outflow into high energy ($\geq 100$~MeV) $\gamma$-rays through the production
and decay of $\pi^0$-mesons can be higher, up to $10^{-2}$ of the accretion
luminosity. We show that in the ADAF model up to 15 percent of the mass of
accretion matter can `evaporate' in the form of neutrons.
