  A Large Ion Collider Experiment (ALICE) at the Large Hadron Collider (LHC)
has been built in order to study the Quark-Gluon Plasma (QGP) created in
high-energy nuclear collisions. As heavy-flavor quarks are produced at the
early stage of the collision, they serve as sensitive probes for the QGP. The
ALICE detector with its capabilities such as particle identification, secondary
vertexing and tracking in a high multiplicity environment can address, among
other measurements, the heavy-flavor sector in heavy-ion collisions. We present
latest results on the measurement of the nuclear modification factor of open
heavy-flavors as well as on the measurement of open heavy-flavor azimuthal
anisotropy v2 in Pb-Pb collisions at sqrt(s) = 2.76 TeV. Open charmed hadrons
are reconstructed in the hadronic decay channels D0->Kpi, D+->Kpipi, and
D*+->D0pi applying a secondary decay-vertex topology. Complementary
measurements are performed by detecting electrons (muons) from semi-leptonic
decays of open heavy-flavor hadrons in the central (forward) rapidity region.
