  Gene expression data sets are used to classify and predict patient diagnostic
categories. As we know, it is extremely difficult and expensive to obtain gene
expression labelled examples. Moreover, conventional supervised approaches
cannot function properly when labelled data (training examples) are
insufficient using Support Vector Machines (SVM) algorithms. Therefore, in this
paper, we suggest Transductive Support Vector Machines (TSVMs) as
semi-supervised learning algorithms, learning with both labelled samples data
and unlabelled samples to perform the classification of microarray data. To
prune the superfluous genes and samples we used a feature selection method
called Recursive Feature Elimination (RFE), which is supposed to enhance the
output of classification and avoid the local optimization problem. We examined
the classification prediction accuracy of the TSVM-RFE algorithm in comparison
with the Genetic Learning Across Datasets (GLAD) algorithm, as both are
semi-supervised learning methods. Comparing these two methods, we found that
the TSVM-RFE surpassed both a SVM using RFE and GLAD.
