  All of the present methods for calibration and monitoring of TOF-PET scanner
detectors utilize radioactive isotopes such as e.g. $^{22}$Na or $^{68}$Ge,
which are placed or rotate inside the scanner. In this article we describe a
novel method based on the cosmic rays application to the PET calibration and
monitoring methods. The concept allows to overcome many of the drawbacks of the
present methods and it is well suited for newly developed TOF-PET scanners with
a large longitudinal field of view. The method enables also monitoring of the
quality of the scintillator materials and in general allows for the continuous
quality assurance of the PET detector performance.
