  Cancer is a complex disease that is characterized by uncontrolled growth and
division of cells. It involves a complex interplay between genetic and
environmental factors that lead to the initiation and progression of tumors.
Recent advances in molecular dynamics simulations have revolutionized our
understanding of the molecular mechanisms underlying cancer initiation and
progression. Molecular dynamics simulations enable researchers to study the
behavior of biomolecules at an atomic level, providing insights into the
dynamics and interactions of proteins, nucleic acids, and other molecules
involved in cancer development. In this review paper, we provide an overview of
the latest advances in molecular dynamics simulations of cancer cells. We will
discuss the principles of molecular dynamics simulations and their applications
in cancer research. We also explore the role of molecular dynamics simulations
in understanding the interactions between cancer cells and their
microenvironment, including signaling pathways, proteinprotein interactions,
and other molecular processes involved in tumor initiation and progression. In
addition, we highlight the current challenges and opportunities in this field
and discuss the potential for developing more accurate and personalized
simulations. Overall, this review paper aims to provide a comprehensive
overview of the current state of molecular dynamics simulations in cancer
research, with a focus on the molecular mechanisms underlying cancer initiation
and progression.
