  Despite its endemic nature as well as the recent outbreaks, information on
the opportunistic DENV in Anambra state has been sparse. This study thus aimed
to give seroepidemiological evidence of past dengue virus infection among
HIV-infected patients in Onitsha, Anambra State, Nigeria. Plasma from 94
HIV-infected patients who were attending Saint Charles Borromeo Hospital,
Onitsha in Anambra State, Nigeria was tested for IgG antibodies specific to the
dengue virus by IgG ELISA assay. The prevalence of past dengue virus infection
was 61.7% (n = 58/94). This study showed age group 0-15 years (77.30%), female
gender (65.1%), married (63.9%) and no formal level (100.0 %) as the highest
seropositivity among the study participants. In terms of immunological and
virological markers, greater IgG seroprevalence was observed in individuals
with a viral load of <40 copies/ml (64.0%) and a CD4 count of >350 cells/ul
(63.2%). The high IgG seropositivity of Dengue Virus (DENV) among HIV-infected
individuals on Onitsha is cause for concern.
