  Proton decay, and the decay of nucleons in general, constitutes one of the
most sensitive probes of high-scale physics beyond the Standard Model. Most of
the existing nucleon decay searches have focused primarily on two-body decay
channels, motivated by Grand Unified Theories and supersymmetry. However, many
higher-dimensional operators violating baryon number by one unit, $\Delta B =
1$, induce multi-body nucleon decay channels, which have been only weakly
constrained thus far. While direct searches for all such possible channels are
desirable, they are highly impractical. In light of this, we argue that
inclusive nucleon decay searches, $N \rightarrow X +$anything (where $X$ is a
light Standard Model particle with an unknown energy distribution), are
particularly valuable, as are model-independent and invisible nucleon decay
searches such as $n \rightarrow$ invisible. We comment on complementarity and
opportunities for such searches in the current as well as upcoming large-scale
experiments Super-Kamiokande, Hyper-Kamiokande, JUNO, and DUNE. Similar
arguments apply to $\Delta B >1$ processes, which kinematically allow for even
more involved final states and are essentially unexplored experimentally.
