  Modulating extracellular matrix (ECM) elasticity with fibrillar collagen
offers great potential for regenerative medicine, drug discovery, and disease
modeling by replicating invivo mechanical signals. This enhances understanding
of cellular responses and fosters therapeutic innovation. However, precise ECM
elasticity measurements are still lacking. This study couples time-resolved
Brillouin spectroscopy and pulsed laser-induced Scholtes wave generation. We
measure how collagen fibrillation affects sound velocity and refractive index.
These insights are advancing tissue engineering and cellular biomechanics.
