  A novel Monte Carlo technique of simulation of spatial fluorescence
distribution within the human skin is presented. The computational model of
skin takes into account the spatial distribution of fluorophores, which would
arise due to the structure of collagen fibres, compared to the epidermis and
stratum corneum where the distribution of fluorophores is assumed to be
homogeneous. The results of simulation suggest that distribution of auto-
fluorescence is significantly suppressed in the near-infrared spectral region,
whereas the spatial distribution of fluorescence sources within a sensor layer
embedded in the epidermis is localized at an effective depth.
