  The identification of the electromagnetic counterpart of the gravitational
wave event, GW170817, and discovery of neutrinos and gamma-rays from TXS
0506+056 heralded the new era of multi-messenger astrophysics. As the number of
multi-messenger events rapidly grow over the next decade, the
cyberinfrastructure requirements to handle the increase in data rates, data
volume, need for event follow up, and analysis across the different messengers
will also explosively grow. The cyberinfrastructure requirements to enhance
multi-messenger astrophysics will both be a major challenge and opportunity for
astronomers, physicists, computer scientists and cyberinfrastructure
specialists. Here we outline some of these requirements and argue for a
distributed cyberinfrastructure institute for multi-messenger astrophysics to
meet these challenges.
