  Scientific computing often requires the availability of a massive number of
computers for performing large scale experiments. Traditionally, these needs
have been addressed by using high-performance computing solutions and installed
facilities such as clusters and super computers, which are difficult to setup,
maintain, and operate. Cloud computing provides scientists with a completely
new model of utilizing the computing infrastructure. Compute resources, storage
resources, as well as applications, can be dynamically provisioned (and
integrated within the existing infrastructure) on a pay per use basis. These
resources can be released when they are no more needed. Such services are often
offered within the context of a Service Level Agreement (SLA), which ensure the
desired Quality of Service (QoS). Aneka, an enterprise Cloud computing
solution, harnesses the power of compute resources by relying on private and
public Clouds and delivers to users the desired QoS. Its flexible and service
based infrastructure supports multiple programming paradigms that make Aneka
address a variety of different scenarios: from finance applications to
computational science. As examples of scientific computing in the Cloud, we
present a preliminary case study on using Aneka for the classification of gene
expression data and the execution of fMRI brain imaging workflow.
