  Safety assurance is of paramount importance across various domains, including
automotive, aerospace, and nuclear energy, where the reliability and
acceptability of mission-critical systems are imperative. This assurance is
effectively realized through the utilization of Safety Assurance Cases. The use
of safety assurance cases allows for verifying the correctness of the created
systems capabilities, preventing system failure. The latter may result in loss
of life, severe injuries, large-scale environmental damage, property
destruction, and major economic loss. Still, the emergence of complex
technologies such as cyber-physical systems (CPSs), characterized by their
heterogeneity, autonomy, machine learning capabilities, and the uncertainty of
their operational environments poses significant challenges for safety
assurance activities. Several papers have tried to propose solutions to tackle
these challenges, but to the best of our knowledge, no secondary study
investigates the trends, patterns, and relationships characterizing the safety
case scientific literature. This makes it difficult to have a holistic view of
the safety case landscape and to identify the most promising future research
directions. In this paper, we, therefore, rely on state-of-the-art bibliometric
tools(e.g., VosViewer) to conduct a bibliometric analysis that allows us to
generate valuable insights, identify key authors and venues, and gain a birds
eye view of the current state of research in the safety assurance area. By
revealing knowledge gaps and highlighting potential avenues for future
research, our analysis provides an essential foundation for researchers,
corporate safety analysts, and regulators seeking to embrace or enhance safety
practices that align with their specific needs and objectives.
