  Mechanical single molecule experiments probe the energy profile of
biomolecules. We show that in the case of a profile with two minima (like
folded/unfolded) periodic driving leads to a stochastic resonance-like
phenomenon. We demonstrate that the analysis of such data can be used to
extract four basic parameters of such a transition and discuss the statistical
requirements of the data acquisition. As advantages of the proposed scheme, a
polymeric linker is explicitly included and thermal fluctuations within each
well need not to be resolved.
