  Recent advances in brain organoid technology are exciting new ways, which
have the potential to change the way how doctors and researchers understand and
treat cerebral diseases. Despite the remarkable use of brain organoids derived
from human stem cells in new drug testing, disease modeling, and scientific
research, it is still heavily time-consuming work to observe and analyze the
internal structure, cells, and neural inside the organoid by humans,
specifically no standard quantitative analysis method combined growing AI
technology for brain organoid. In this paper, an automated computer-assisted
analysis method is proposed for brain organoid slice channels tagged with
different fluorescent. We applied the method on two channels of two group
microscopy images and the experiment result shows an obvious difference between
Wild Type and Mutant Type cerebral organoids.
