  Epidemic outbreaks are an important healthcare challenge, especially in
developing countries where they represent one of the major causes of mortality.
Approaches that can rapidly target subpopulations for surveillance and control
are critical for enhancing containment processes during epidemics.
  Using a real-world dataset from Ivory Coast, this work presents an attempt to
unveil the socio-geographical heterogeneity of disease transmission dynamics.
By employing a spatially explicit meta-population epidemic model derived from
mobile phone Call Detail Records (CDRs), we investigate how the differences in
mobility patterns may affect the course of a realistic infectious disease
outbreak. We consider different existing measures of the spatial dimension of
human mobility and interactions, and we analyse their relevance in identifying
the highest risk sub-population of individuals, as the best candidates for
isolation countermeasures. The approaches presented in this paper provide
further evidence that mobile phone data can be effectively exploited to
facilitate our understanding of individuals' spatial behaviour and its
relationship with the risk of infectious diseases' contagion. In particular, we
show that CDRs-based indicators of individuals' spatial activities and
interactions hold promise for gaining insight of contagion heterogeneity and
thus for developing containment strategies to support decision-making during
country-level pandemics.
