  We discuss the Yukawa coupling unification, a very interesting prediction of
the grand unified theory, in the context of scenarios with more than one pair
of Higgs doublet since the current LHC constraint has become a problem for the
Yukawa unification scenarios with just one pair of Higgs doublet. More than one
pair of Higgs doublets can easily arise in missing partner mechanism which
solves the doublet-triplet splitting problem. In such a scenario, the Yukawa
unification occurs at a medium $\tan\beta$ value, e.g., $\sim$ 30, which
corresponds to much smaller threshold corrections compared to usual large
$\tan\beta$ scenario for $t-b-\tau$ unification in the context of SO(10) and
$b-\tau$ unification in the context of SU(5) models. Further, we show that an
additional Higgs doublet pair lowers the sensitivity of the radiative symmetry
breaking of the electroweak vacuum.
