  We consider supersymmetric deformations of gauge theories in various
dimensions obtained from a String Theory realisation of branes embedded in flux
backgrounds. In particular we obtain deformations which take the form of Wilson
line defects, where the R-symmetry is twisted into the gauge symmetry.
Furthermore we construct higher-order generalisations, also expressed a
twisting of the R-symmetry, that have symmetries associated to co-dimension two
and three defects.
