  Within the context of vector mediators, is a new signal observed in flavor
changing interactions, particularly in the neutral mesons systems
$K^{0}-\bar{K}^{0}$, $D^{0}-\bar{D}^{0}$ and $B^0-\bar{B^0}$, consistent with
dilepton resonance searches at the LHC? In the attempt to address this very
simple question, we discuss the complementarity between flavor changing neutral
current (FCNC) and dilepton resonance searches at the LHC run 2 at $13$TeV with
$3.2\, {\rm fb^{-1}}$ of integrated luminosity, in the context of vector
mediators at tree level. Vector mediators, are often studied in the flavor
changing framework, specially in the light of the recent LHCb anomaly observed
at the rare B decay. However, the existence of stringent dilepton bound
severely constrains flavor changing interactions, due to restrictive limits on
the $Z^{\prime}$ mass. We discuss this interplay explicitly in the well
motivated framework of a 3-3-1 scheme, where fermions and scalars are arranged
in the fundamental representation of the weak SU(3) gauge group. Due to the
paucity of relevant parameters, we conclude dilepton data leave little room for
a possible new physics signal stemming from these systems, unless a very
peculiar texture parametrization is used in the diagonalization of the CKM
matrix. In other words, if a signal is observed in such flavor changing
interactions, it is unlikely comes from a 3-3-1 model.
