  We explicitly test the asymptotic grand unification of a minimal
5-dimensional model with SO(10) gauge theory compactified on an
$S^{1}/Z_{2}\times Z^{\prime}_{2}$ orbifold. We consider all matter fields as
propagating in the bulk and show that the gauge couplings asymptotically run to
a fixed point in the UV. However, the Yukawa couplings will typically hit a
Landau pole right above the compactification scale in this class of SO(10)
models.
