  We present the first results of an ongoing variability monitoring program of
active galactic nuclei (AGNs) using the 46\,cm telescope of the Wise
observatory in Israel. The telescope has a field of view of $1.25^{\circ}
\times 0.84^{\circ}$ and is specially equipped with five narrow band filters at
4300, 5200, 5700, 6200 and 7000\,\AA\, in order to perform photometric
reverberation mapping studies of the central engine of AGNs. The program aims
to observe a sample of 27 AGNs (V $<17$ mag) selected according to tentative
continuum and line time delay measurements obtained in previous works. We
describe the autonomous operation of the telescope together with the fully
automatic pipeline used to achieve high-performance unassisted observations,
data reduction, and light curves extraction using different photometric
methods. The science verification data presented here, demonstrates the
performance of the monitoring program in particular for efficiently photometric
reverberation mapping of AGNs with additional capabilities to carry out
complementary studies of other transient and variable phenomena such as
variable stars studies.
