  We argue that the entanglement of purification for two dimensional
holographic CFT can be obtained from conformal blocks with internal twist
operators. First, we explain our formula from the view point of tensor network
model of holography. Then, we apply it to bipartite mixed states dual to
subregion of AdS${}_3$ and the static BTZ blackhole geometries. The formula in
CFT agrees with the entanglement wedge cross section in the bulk, which has
been recently conjectured to be equivalent to the entanglement of purification.
