  In the recently published article by T.M. Gray et al. "Microdosimetric and
radiobiological effects of gold nanoparticles at therapeutic radiation
energies" (IJRB 2023, 99(2), 308-317) results of Monte Carlo simulations and
radiobiological assays on the dosimetric effects of gold nanoparticles were
presented. This commentary points out that the results of the two parts of the
study are in contradiction and that the predicted magnitude of dose enhancement
and its dependence on the shape of the nanoparticle appear implausible.
Possible reasons for these observations are discussed.
