  We consider a class of degenerate Ornstein-Uhlenbeck operators in
$\mathbb{R}^{N}$, of the kind \[
\mathcal{A}\equiv\sum_{i,j=1}^{p_{0}}a_{ij}\partial_{x_{i}x_{j}}^{2}
+\sum_{i,j=1}^{N}b_{ij}x_{i}\partial_{x_{j}}% \] where $(a_{ij}) ,(b_{ij}) $
are constant matrices, $(a_{ij}) $ is symmetric positive definite on
$\mathbb{R} ^{p_{0}}$ ($p_{0}\leq N$), and $(b_{ij}) $ is such that
$\mathcal{A}$ is hypoelliptic. For this class of operators we prove global
$L^{p}$ estimates ($1<p<\infty$) of the kind:% \[ \Vert
\partial_{x_{i}x_{j}}^{2}u\Vert_{L^{p}(\mathbb{R}% ^{N})}\leq c\{\Vert
\mathcal{A}u\Vert_{L^{p}(\mathbb{R}^{N})}+\Vert u\Vert_{L^{p}(\mathbb{R}%
^{N})}\} \text{for}i,j=1,2,...,p_{0}% \] and corresponding weak (1,1)
estimates. This result seems to be the first case of global estimates, in
Lebesgue $L^{p}$ spaces, for complete H\"{o}rmander's operators $ \sum
X_{i}^{2}+X_{0},$ proved in absence of a structure of homogeneous group. We
obtain the previous estimates as a byproduct of the following one, which is of
interest in its own:% \[ \Vert \partial_{x_{i}x_{j}}^{2}u\Vert_{L^{p}(S)}\leq
c\Vert Lu\Vert_{L^{p}(S)}% \] for any $u\in C_{0}^{\infty}(S) ,$ where $S$ is
the strip $\mathbb{R}^{N}\times[ -1,1] $ and $L$ is the
Kolmogorov-Fokker-Planck operator $\mathcal{A}-\partial_{t}.$
