  We propose a simple model for scaffold aided bone regeneration. In this
model, only macroscopic quantities, e.g., locally averaged osteoblast
densities, are considered. This allows for use of this model in an optimization
algorithm, whose outcome is an optimal scaffold porosity distribution. This
optimal scaffold naturally depends on the choice of parameters in the model,
and we provide a parameter study with a particular focus on patients with
reduced bone regeneration or reduced vascularization capacity.
