  All-dielectric nanophotonics becomes a versatile tool for various optical
applications, including nanothermometry and optical heating. Its general
concept includes excitation of Mie resonances in nonplasmonic nanoparticles.
However, the potential of resonant dielectric nanoparticles in drug delivery
applications still have not been fully realized. Here, optically resonant
dielectric iron oxide nanoparticles ($\alpha$-Fe$_2$O$_3$ NPs) are employed for
remote rupture of microcontainers used as drug delivery platform. It is
theoretically and experimentally demonstrated, that $\alpha$-Fe$_2$O$_3$ NPs
has several advantages in light-to-heat energy conversion comparing to
previously used materials, such as noble metals and silicon, due to the broader
spectral range of efficient optical heating, and in enhancement of thermally
sensitive Raman signal. The $\alpha$-Fe$_2$O$_3$ NPs embedded into the wall of
universal drug carriers, polymer capsules, are used to experimentally determine
the local temperature of the capsule rupture upon laser irradiation (170$^o$C).
As a proof of principle, we successfully show the delivery and remote release
of anticancer drug vincristine upon lowered laser irradiation
(4.0$\times$10$^4$~W/cm$^2$) using polymer capsules modified with the
$\alpha$-Fe$_2$O$_3$ NPs. The biological tests were performed on two primary
cell types: (i) carcinoma cells, as an example of malignant tumor, and (ii)
human stem cells, as a model of healthy cells. The developed delivery system
consisting of polymer capsules modified with the dielectric nanoparticles
provides multifunctional platform for remote drug release and temperature
detection.
