  In these proceedings we review the flavour phenomenology of 2HDMs with
generic Yukawa structures. We first consider the quark sector and find that
despite the stringent constraints from FCNC processes large effects in tauonic
B decays are still possible. We then consider lepton flavour observables, show
correlations between \mu -> e\gamma and \mu^- -> e^-e^+e^- in the 2HDM of type
III and give upper bounds on the lepton flavour violating B decay B_d -> \mu e.
