  Density perturbations at the decoupling epoch produce angular fluctuations in
the temperature of the Cosmic Microwave Background (CMB) radiation that may
appear as hot and cold spots. Observational data of the CMB includes
instrumental noise in addition to the cosmological signal. One would like to
determine which of the observed spots are produced by the noise and which
correspond to signal. In this work we first present a statistical analysis of
the first plus second year COBE/DMR map at 53 GHz that reveals the presence of
cosmological signal in the data. The analysis is based on Harrison-Zeldovich
Monte Carlo realizations and utilizes a generalized $\chi^2$ statistic. The
method is applied to the number of spots and the fraction of the total area
that appear above/below a certain value of the dispersion of the noise,
including and excluding the quadrupole, giving $Q_{rms-PS}=15^{+3}_{-6}$,
$18^{+5}_{-7} \mu K$ and $Q_{rms-PS}=18^{+3}_{-4}$, $21\pm6 \mu K$, at the
$95\%$ confidence level, respectively. The data taken by the COBE/DMR
experiment during the first two years at three different frequencies (31, 53
and 90 GHz) are used to determine which of the spots observed at 53 GHz appear
simultaneously in the other two channels. The significance of those spots is
determined by comparison of their area and signal-to-noise with noise Monte
Carlo simulations. We point out two cold spots and one hot spot at positions
$(l,b)\approx (-99^{\circ},57^{\circ}),(-21^{\circ},-45^{\circ}),
(-81^{\circ},-33^{\circ})$ respectively, at the $95 \%$ confidence level.
