  The hydrogen bond is a fundamental ingredient to stabilize the DNA and RNA
macromolecules. The main contribution of this work is to describe
quantitatively this interaction as a consequence of the quantum confinement of
the hydrogen. The results for the free and confined system are compared with
experimental data. The formalism to compute the energy gap of the vibration
motion used to identify the spectrum lines is the Variational Method allied to
Supersymmetric Quantum Mechanics.
