  We discussed neutrino masses and mixings in SUSY SO(10) model where quarks
and leptons have Yukawa couplings to at least two 10 and one $\bar{126}$ Higgs
scalars. In this model, the Dirac and the right-handed Majorana mass terms are
expressed by linear combinations of quark and charged lepton mass matrices,
which then determine the neutrino mass matrix by the see-saw mechanism. We show
that there are various solutions to reproduce a large mixing angle for
$\nu_\mu-\nu_\tau$ and a small mixing angle for $\nu_e-\nu_\mu$, as well as the
hierarchical mass spectrum of neutrinos.
