  This work presents a contemporary treatment of Krein's entire operators with
deficiency indices $(1,1)$ and de Branges' Hilbert spaces of entire functions.
Each of these theories played a central role in the research of both renown
mathematicians. Remarkably, entire operators and de Branges spaces are
intimately connected and the interplay between them has had an impact in both
spectral theory and the theory of functions. This work exhibits the
interrelation between Krein's and de Branges' theories by means of a functional
model and discusses recent developments, giving illustrations of the main
objects and applications to the spectral theory of difference and differential
operators.
