  We report SInC (SNV, Indel and CNV) simulator and read generator, an
open-source tool capable of simulating biological variants taking into account
a platform-specific error model. SInC is capable of simulating and generating
single- and paired-end reads with user-defined insert size with high efficiency
compared to the other existing tools. SInC, due to its multi-threaded
capability during read generation, has a low time footprint. SInC is currently
optimised to work in limited infrastructure setup and can efficiently exploit
the commonly used quad-core desktop architecture to simulate short sequence
reads with deep coverage for large genomes. Sinc can be downloaded from
https://sourceforge.net/projects/sincsimulator/.
