  Amino acids occurring in proteins are, with rare exceptions, exclusively of
the L-configuration. Among the many scenarios put forward to explain the origin
of this chiral homogeneity (i.e., homochirality), one involves the asymmetric
photolysis of amino acids present in space, triggered by circularly polarized
UV radiation. The recent observation of circularly polarized light (CPL) in the
Orion OMC-1 star-forming region (Bailey et al. 1998, Science 281, 672) has been
presented as providing a strong validation of this scenario. The present paper
reviews the situation. It is stressed for example that one important condition
for the asymmetric photolysis by CPL to be at the origin of the terrestrial
homochirality of natural amino acids is generally overlooked, namely, the
asymmetric photolysis should favour the L-enantiomer for ALL the primordial
amino acids involved in the genesis of life (i.e., biogenic amino acids).
Although this condition is probably satisfied for aliphatic amino acids, some
non-aliphatic amino acids like tryptophan and proline may violate the condition
and thus invalidate the asymmetric photolysis scenario, assuming they were
among the primordial amino acids. Alternatively, if CPL photolysis in space is
indeed the source of homochirality of amino acids, then tryptophan and proline
may be crossed out from the list of biogenic amino acids.
