  In this article, a new conceptual biomedical engineering strategy to tackle
modern disease challenges, termed as liquid metal enabled electrobiology, is
proposed. This generalized and easy going way is based on the physiological
fact that specially administrated electricity would induce a series of
subsequent desired biological effects, either shortly, transitional or
permanently. Owing high compliance within any part of the biological tissues,
the liquid metal would aid to mold a pervasive way to treat physiological or
psychological diseases. As highly conductive and non-toxic multifunctional
flexible materials, such liquid metals (LMs) consist of the core to generate
any requested electric treating fields (ETFields) which can adapt to various
sites inside the human body. The basic mechanisms of electrobiology in
delivering electricity to the target tissues and then inducing expected outputs
for disease treatment are interpreted. The methods toward realizing soft and
conformable electronics based on liquid metal are illustrated. Further, a group
of typical disease challenges were taken to illustrate the basic strategies to
perform liquid metal electrobiology therapy, which include but are not limited
to: tissue electronics, brain disorder, immunotherapy, neural functional
recovery, muscle stimulation, skin rejuvenation, cosmetology and dieting,
artificial organs, cardiac pacing and cancer therapy etc. Some practical issues
involved in the electrobiology for future disease therapy were discussed.
Perspective along this direction to incubate an easy-going biomedical tool for
health care was pointed out.
