  In this article I study the distribution of spiral galaxies in the Sloan
Digital Sky Survey (SDSS) to investigate whether the universe has an overall
handedness. A preference for spiral galaxies in one sector of the sky to be
left-handed or right-handed spirals would indicate a preferred handedness. The
SDSS data show a strong signal for such an asymmetry with a probability <0.2%.
The asymmetry axis is at (RA,dec) ~(202 deg,25 deg) with an uncertainty ~15
deg. The axis appears to be correlated with that of the quadrupole and octopole
moments in the WMAP microwave sky survey, an unlikely alignment that has been
dubbed "the axis of evil". Our Galaxy is aligned with its spin axis along the
same direction as the majority of the spirals.
