  In this work, the impact of recent measurements of heavy-flavour production
in $pp$ collisions on parton distribution functions (PDFs) and their
uncertainties is studied. In this regard, the absolute and normalised cross
sections of beauty hadron production measured by LHCb at center-of-mass energy
of 7 TeV and 13 TeV are separately included in the next-to-leading order (NLO)
global QCD analysis together with the measurements of the inclusive and
heavy-flavour production cross sections at HERA. It is illustrated that the
heavy-flavour data of the LHCb experiment impose additional constraints on the
PDFs, especially on the gluon distribution at low partonic fractions $x$ of the
proton momentum. One of the most important results of the present analysis is
the significant reduction of the gluon uncertainties in the region less than
$x=10^{-4}$ that can play a crucial rule in many areas of high energy physics
investigations.
