  Chargaff once said that "I saw before me in dark contours the beginning of a
grammar of Biology". In linguistics, "grammar" is the set of natural language
rules, but we do not know for sure what Chargaff meant by "grammar" of Biology.
Nevertheless, assuming the metaphor, Chargaff himself started a "grammar of
Biology" discovering the so called Chargaff's rules. In this work, we further
develop his grammar. Using new concepts, we were able to discovery new genomic
rules that seem to be invariant across a large set of organisms, and show a
fractal-like property, since no matter the scale, the same pattern is observed
(self-similarity). We hope that these new invariant genomic rules may be used
in different contexts since short read data bias detection to genome assembly
quality assessment.
