  The first measurement of the top quark pair ($\mathrm{t\bar{t}}$) production
cross section in proton-proton collisions at $\sqrt{s}$ = 13.6 TeV is
presented. Data recorded with the CMS detector at the CERN LHC in Summer 2022,
corresponding to an integrated luminosity of 1.21 fb$^{-1}$, are analyzed.
Events are selected with one or two charged leptons (electrons or muons) and
additional jets. A maximum likelihood fit is performed in event categories
defined by the number and flavors of the leptons, the number of jets, and the
number of jets identified as originating from b quarks. An inclusive
$\mathrm{t\bar{t}}$ production cross section of 881 $\pm$ 23 (stat+syst) $\pm$
20 (lumi) pb is measured, in agreement with the standard model prediction of
924 $^{+32}_{-40}$ pb.
