  In this paper, we study the complex symmetry of weighted
composition-differentiation operator $D_{n, \psi, \phi}$ on weighted Bergman
spaces $\mathcal{A}^2_{\alpha}$ with respect to the conjugation $C_{\mu, \eta}$
for $\mu, \eta \in \{z\in \mathbb{C}:|z|=1\}$. We obtain explicit conditions
for which the operator $D_{n, \psi, \phi}$ is Hermitian and normal. We also
characterize the complex symmetric weighted composition-differentiation
operator for derivative Hardy spaces.
