  We report two techniques to mitigate stripe artifacts in light-sheet
fluorescence imaging. The first uses an image processing algorithm called the
multidirectional stripe remover (MDSR) method to filter stripes from an
existing image. The second uses an elliptical holographic diffuser (EHD) with
strong scattering anisotropy to prevent stripe formation during image
acquisition. These techniques facilitate accurate interpretation of image data,
especially in denser samples. They are also facile and cost-effective.
