  We analyze response of a macromolecule near to a substrate; the substrate is
tiled in the sequential and specific manner so that repeat units of the
macromolecule may have different response on its adsorption in different
directions onto the substrate. The lattice model of random walk has been used
to analyze the adsorption-desorption behavior of an infinitely long
homo-polymer molecule on a sequentially tiled substrate in three dimensions.
The lattice model for the Gaussian chain and directed self-avoiding chain has
been solved analytically. It has been emphasized on the basis of analytical
estimates that a suitable coating may modify affinity of the macromolecule on
the living surfaces and on the non living substrates in the complex manner
which may be suitable means to control growth and also a route to restrict the
spread of the deadly microbes.
