  I report B physics results from the CLEO collaboration, highlighting
measurements of the Cabibbo-Kobayashi-Maskawa matrix elements |Vcb| and |Vub|.
I report a recent measurement of |Vub| through study of the q^2 dependence of B
-> pi l nu and B -> rho l nu. I also describe new measurements of the inclusive
semileptonic branching fraction BF(B -> X e nu) and of moments of the hadronic
invariant mass spectrum in B -> X l nu, with impact on |Vcb|.
