  A new generation of molecular tools for analyzing neural activity has been
contributing to elucidate classical open questions in neuroscience. With
enhanced GEVIs and advanced optical imaging techniques, voltage-imaging
technologies have been increasingly used to observe the dynamics of large
circuits. In this chapter, we describe how to combine cortical wide-field
voltage imaging with hippocampal electrophysiology in awake behaving mice.
Furthermore, we highlight how this method can be useful for different possible
investigations.
