  We discuss the role of QCD symmetries and confinement in understanding eta
and etaprime mesic nuclei. Eta and etaprime bound states in nuclei are
sensitive to the flavour-singlet component in the meson. The bigger the singlet
component, the more attraction and the greater the binding. Recent results on
the etaprime mass in nuclei from the CBELSA/TAPS collaboration are very similar
to the prediction of the Quark Meson Coupling model. In the model eta-etaprime
mixing induces a factor of two enhancement of the eta-nucleon scattering length
relative to the prediction with a pure octet eta, with real part about 0.8 fm.
