  The coding sequence in DNA molecule is considered as a message to be
transferred to receiver, the proteins, through a noisy information channel and
each nucleotide is assigned a respective information weight. With the help of
the nucleotide substitution matrix we estimated the lower bound of the amount
of information carried out by nucleotides which is not subject of mutations. We
used the calculated weights to reconstruct k-oligomers of genes from the
Borrelia burgdorferi genome. We showed, that to this aim there is sufficient a
simple rule, that the number of bits of the carried information cannot exceed
some threshold value. The method introduced by us is general and applies to
every genome.
