  Synthetic materials and heterostructures obtained by the controlled stacking
of exfoliated monolayers are emerging as attractive functional materials owing
to their highly tunable properties. We present a detailed scanning tunneling
microscopy and spectroscopy study of single layer MoS$_2$-on-gold
heterostructures as a function of twist angle. We find that their electronic
properties are determined by the hybridization of the constituent layers and
are modulated at the moir\'e period. The hybridization depends on the layer
alignment and the modulation amplitude vanishes with increasing twist angle. We
explain our observations in terms of a hybridization between the nearest sulfur
and gold atoms, which becomes spatially more homogeneous and weaker as the
moir\'e periodicity decreases with increasing twist angle, unveiling the
possibility of tunable hybridization of electronic states via twist angle
engineering.
