  We study the prospect of probing electroweak baryogenesis driven by an extra
bottom Yukawa coupling $\rho_{bb}$ in a general two Higgs doublet model via
electric dipole moment (EDM) measurements and at the collider experiments. The
parameter space receives meaningful constraints from 125 GeV Higgs $h$ boson
signal strength measurements as well as several heavy Higgs boson searches at
the Large Hadron Collider (LHC). In addition, we show that the asymmetry of the
CP asymmetry of inclusive $B\to X_s \gamma$ decay would provide complementary
probe. A discovery is possible at the LHC via $bg\to bA \to b Z h$ process if
$|\rho_{bb}|\sim 0.15$ and $250~\mbox{GeV}\lesssim m_A \lesssim 350$ GeV, where
$A$ is CP odd scalar. For $m_A> 2 m_t$ threshold, where $m_t$ is the top quark
mass, one may also discover $bg\to bA \to b t \bar t$ at the high luminosity
LHC run if an extra top Yukawa coupling $|\rho_{tt}|\sim0.5$, though it may
suffer from systematic uncertainties. For completeness we study $gg\to t \bar t
A \to t \bar t b \bar b $ but find it not promising.
