  Inverse spectroscopic optical coherence tomography (IS-OCT) methods apply
inverse problem formulations to acquired spectra to estimate depth-resolved
sample properties. In the current study, we modelled the
time-frequency-distributions using Lambert-Beer law and implemented IS-OCT
using backscattering spectra calculated from Mie theory, then demonstrated the
algorithm on polystyrene microspheres under idealized conditions. The results
are significant because the method generates depth dependent estimates of both
the concentration and diameter of scattering particles.
