  The time-dependent density functional theory (TDDFT) provides a unified
description of the structure and reaction. The linear approximation leads to
the random-phase approximation (RPA) which is capable of describing a variety
of collective motion in a harmonic regime. Beyond the linear regime, we present
applications of the TDDFT to nuclear fusion and fission reaction. In
particular, the extraction of the internuclear potential and the inertial mass
parameter is performed using two different methods. A fusion hindrance
mechanism for heavy systems is investigated from the microscopic point of view.
The canonical collective variables are determined by the adiabatic
self-consistent collective coordinate method. Preliminary results of the
spontaneous fission path, the potential, and the collective mass parameter are
shown for 8Be --> alpha+alpha.
