  The TYPHOON program is producing an atlas of spectroscopic data cubes of 44
large-angular-sized galaxies with complete spatial coverage from 3650-9000 A.
This survey provides an unparalleled opportunity to study variations in the
interstellar medium (ISM) properties within individual HII regions across the
entire star-forming disks of nearby galaxies. This can provide key insights
into the spatial distribution and resolved properties of the ISM to understand
how efficiently metals are mixed and redistributed across spirals and dwarf
galaxies. In this Proceeding, we present early science results from six nearby
spiral galaxies as part of the TYPHOON program from Grasha et al. (2022). We
use HIIPhot to identify the HII regions within the galaxy based on the surface
brightness of the H-alpha emission line and measure variations of the HII
region oxygen abundance. In this initial work, we find that while the spiral
pattern plays a role in organizing the ISM, it alone does not establish the
relatively uniform azimuthal variations we observe across all the galaxies.
Differences in the metal abundances are more likely driven by the strong
correlations with the local physical conditions. We find a strong and positive
correlation between the ionization parameter and the local abundances as
measured by the relative metallicity offset $\Delta$(O/H), indicating a tight
relationship between local physical conditions and their localized enrichment
of the ISM. These variations can be explained by a combination of localized,
star formation-driven self-enrichment and large-scale mixing-driven dilution
due to the passing of spiral density waves.
