  The Intelligent Transportation System (ITS) is an important part of modern
transportation infrastructure, employing a combination of communication
technology, information processing and control systems to manage transportation
networks. This integration of various components such as roads, vehicles, and
communication systems, is expected to improve efficiency and safety by
providing better information, services, and coordination of transportation
modes. In recent years, graph-based machine learning has become an increasingly
important research focus in the field of ITS aiming at the development of
complex, data-driven solutions to address various ITS-related challenges. This
chapter presents background information on the key technical challenges for ITS
design, along with a review of research methods ranging from classic
statistical approaches to modern machine learning and deep learning-based
approaches. Specifically, we provide an in-depth review of graph-based machine
learning methods, including basic concepts of graphs, graph data
representation, graph neural network architectures and their relation to ITS
applications. Additionally, two case studies of graph-based ITS applications
proposed in our recent work are presented in detail to demonstrate the
potential of graph-based machine learning in the ITS domain.
