  Recently, Molecular Communication (MC) has been recognized as an enabling
technology for nanonetworks where MC is envisioned to enable nanorobots to
achieve sophisticated and complex tasks in the human body for promising medical
applications. Many MC methods that can be applied in the human body have been
proposed and modeled in the literature. However, none of them can be used to
convey information between distant points that are separated by body fluids,
tissues, or placed in different organs. In this paper, we propose a new method
and system for Molecular Communication in the Body, denoted MoSiMe and MoCoBo,
respectively. The method takes advantage of how the absorption, distribution,
metabolization, and elimination (ADME) bodily processes affects drugs, referred
to as Pharmacokinetics (PK) in pharmacology, to enable MC between any points of
the human body regardless of their distance even if they are in different parts
of the body and separated by tissues and fluids. The architecture, design and
components of the MoCoBo system and MoSiMe method are described and different
transmitter designs, including a novel passive transmitter design for the first
time in telecommunications, are introduced. An analytical model for the body
channel is derived and validated with respect to existing human and animal
tests. The model captures the ADME bodily processes that affect the kinetics of
substances administered to the body. Additionally, an experimental MoCoBo proof
of concept platform, capable of reliably sending and receiving a stream of bits
between a transmitter and a receiver, is built and validated against clinical
trials, animal tests and analytical models. The introduced platform can also be
utilized to test modulation techniques and designs for new MoCoBo transmitters
and receivers.
