  The genes of eukaryotes are characterized by protein coding fragments, the
exons, interrupted by introns, i.e. stretches of DNA which do not carry any
useful information for the protein synthesis. We have analyzed the melting
behavior of randomly selected human cDNA sequences obtained from the genomic
DNA by removing all introns. A clear correspondence is observed between exons
and melting domains. This finding may provide new insights in the physical
mechanisms underlying the evolution of genes.
