  The impact of recently calculated next-to-next-to-leading order QCD
corrections and soft gluon resummations on the extraction of higher twist
contributions to the deep-inelastic structure function F_2 is studied using the
BCDMS and SLAC data. It is demonstrated to which extent the need for higher
twist terms is diminishing due to these higher order effects in the kinematical
region, 0.35 \le x \le 0.85 and Q^2>1.2 GeV^2, investigated. In addition,
theoretical uncertainties in the extraction of higher twist contributions are
discussed, and comparisons to results obtained previously are made.
