  Many recent advances in large scale probabilistic inference rely on
variational methods. The success of variational approaches depends on (i)
formulating a flexible parametric family of distributions, and (ii) optimizing
the parameters to find the member of this family that most closely approximates
the exact posterior. In this paper we present a new approximating family of
distributions, the variational sequential Monte Carlo (VSMC) family, and show
how to optimize it in variational inference. VSMC melds variational inference
(VI) and sequential Monte Carlo (SMC), providing practitioners with flexible,
accurate, and powerful Bayesian inference. The VSMC family is a variational
family that can approximate the posterior arbitrarily well, while still
allowing for efficient optimization of its parameters. We demonstrate its
utility on state space models, stochastic volatility models for financial data,
and deep Markov models of brain neural circuits.
