Antipyretics are drugs that prevent or reduce fever by lowering the body temperature from a raised state. However, they will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. Most are also used for other purposes. For example, the most common antipyretics in the United States are aspirin and acetaminophen, which are used primarily as pain relievers. There is some debate over the appropriate use of such medications: fever is part of the body's immune response to infection. Herbal remedies with a fever-reducing effect are called febrifuges, and include catnip, chamomile, sage and yarrow. However, the term "febrifuge" can also refer to a refrigerant, such as topical alcohol, which cools the body by physically removing heat rather than modifying the body's responses. ...more on Wikipedia about "Antipyretic"
Nimesulide is a prescription non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. ...more on Wikipedia about "Nimesulide"
Paracetamol ( INN) or acetaminophen ( USAN) is a common analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. It is a major ingredient in numerous cold and flu medications and many prescription analgesics. It is remarkably safe in standard doses, but, because of its wide availability, deliberate or accidental overdoses are not uncommon. ...more on Wikipedia about "Paracetamol"
Phenacetin, introduced in 1887, is used principly as a analgesic. Typical doses of 300mg to 500mg a day result in an analgesic effect. Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action of the heart, where it acts as a negative inotrope. It also is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type), intercostal neuralgia, and some forms of ataxia. ...more on Wikipedia about "Phenacetin"
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