- The use of several DNA sequence polymorphisms (normal variants)
that are near or within a gene of interest to track within a family the inheritance
of a disease-causing mutation in that gene
Definition from: GeneReviews
from the University of Washington and the National Center for Biotechnology Information
- A gene-hunting technique that traces patterns of heredity in large, high-risk families, in an attempt to locate a disease-causing gene mutation by identifying traits that are co-inherited with it.
Definition from: Office of Rare Diseases
at the National Institutes of Health
See also Understanding Medical Terminology.