Birth defects are structural or functional abnormalities present at birth that cause physical or mental disability. Researchers have identified thousands of different birth defects. Some may be fatal.
About two to three percent of babies born have some type of major birth defect. The risk of some problems, due to abnormal separation of genetic material (chromosomes), increases with the mother’s age. Currently, birth defects are the leading cause of death for infants during the first year of life.
Birth defects have a variety of causes, including the following:
There are two main types of birth defects: structural and functional. Structural birth defects are related to a problem with body parts. Functional birth defects are related to a problem with how a body part or body system works.
Some structural problems include cleft lip or cleft palate, heart defects such as missing or misshaped valves, and abnormal limbs, such as a club foot. They also include neural tube defects such as spina bifida – problems that are related to the growth and development of the brain and spinal cord.
Functional problems often lead to developmental disabilities and can include things such as:
In some cases, birth defects are caused by a combination of factors. Some recognized patterns of birth defects affect many parts or processes in the body, leading to both structural and functional problems.
National Institute of Child Health & Human Development, www.nichd.nih.gov, February 28, 2011.
The Society of Obstetricians and Gynaecologists of Canada (SOGC), www.sogc.org, February 28, 2011.
Treatments for birth defects vary by disorder. Some NTDs can be detected before birth (see below). Some can also be prevented. For example, ensuring sufficient intake of folic acid 3 months before pregnancy and throughout the first trimester can significantly reduce the risks associated with certain neural tube defects, including spina bifida.
For more information, review this website, visit www.sbhao.on.ca and other links on this site, and be sure to talk with your healthcare provider.
Neural tube defects are birth defects that affect the brain (anencephaly) and/or spinal cord (spina bifida). NTDs occur when the tissues that form the brain and spinal cord fail to develop properly. These defects occur in the first four weeks after conception – usually before a woman even knows she is pregnant.
Any woman who could become pregnant is at risk of having a baby with a neural tube defect. About 1 in every 1,300 pregnancies in Canada is affected by NTDs.
High-risk women include those women who:
Some NTDs can be detected before birth. Talk to your healthcare provider if you wish to know more about the prenatal blood test (maternal serum screening, triple test) or ultrasound test that can give you more information about whether your developing baby has a neural tube defect.
The mission of the Spina Bifida & Hydrocephalus Association of Ontario is “to build awareness and drive education, research, support, care and advocacy to help find a cure while always continuing to improve the quality of life of all individuals with spina bifida and/or hydrocephalus.”
Our Folic Acid: It’s never too early… campaign is designed to increase the number of women taking a daily multivitamin containing folic acid and ultimately to prevent the occurence of NTDs.