The Guardian, Friday 24 February 2012
A group of Mexican scientists is working on a vaccine that could reduce addiction to one of the world’s most notorious narcotics: heroin.
Researchers at the country’s National Institute of Psychiatry say they have successfully tested the vaccine on mice and are preparing to test it on humans.
The vaccine, which has been patented in the US, makes the body resistant to the effects of heroin, so users would no longer get a rush of pleasure when they smoked or injected it.
“It would be a vaccine for people who are serious addicts, who have not had success with other treatments and decide to use this application to get away from drugs,” the institute’s director Maria Elena Medina said on Thursday.
Scientists worldwide have been searching for drug addiction vaccines for several years, but none have yet been fully developed. A group at the US National Institute on Drug Abuse has reported significant progress in a vaccine for cocaine.
However, the Mexican scientists appear to be close to making a breakthrough on a heroin vaccine and have received funds from the US institute as well as the Mexican government.
During the tests, mice were given access to deposits of heroin over an extended period of time. Those given the vaccine showed a huge drop in heroin consumption, giving the institute hope that it could also work on people, Medina said.
Kim Janda, a scientist working on his own narcotics vaccines at the Scripps Research Institute in La Jolla, California, said that the Mexican vaccine could function but with some shortcomings.
“It could be reasonably effective, but maybe too general and affect too many different types of opioids as well as heroin,” Janda said.
Mexico has a growing drug addiction problem. Health secretary Jose Cordoba recently said the country now has about 450,000 hard drug addicts, particularly along the trafficking corridors of the US-Mexico border.
Mexican gangsters grow opium poppies in the Sierra Madre mountains and convert them into heroin known as Black Tar and Mexican Mud, which are smuggled over the Rio Grande.
Every year, the heroin trade provides billions of dollars to gangs such as the Sinaloa Cartel and the Zetas. Since 2006, cartel violence has claimed the lives of over 47,000 people in Mexico.