SAN BERNARDINO >> The city saw its 21st and 22nd homicide victims Wednesday afternoon — killed in the second deadly shooting here in 24 hours

Police officers responded around 3:15 p.m. to a deadly car-to-car shooting in the 2900 block of North Pershing Avenue, where a man was dead inside a vehicle and a woman was taken to a local hospital where she died.

There are suspects, but police do not have a good description, said Eileen Hards, San Bernardino police spokeswoman.

• Video: Police investigate double homicide

Officers were canvassing the neighborhood for witnesses into the evening. The shooter’s white vehicle is still outstanding, police officials said.

Although the victims have not been identified, neighbors said they did not believe they lived in the area. Their brown older model Honda crashed into the carport of a home at the corner of 29th Street and Pershing Avenue, south of the 210 Freeway.

Residents of the neighborhood were shocked by the shooting.

• Photos: San Bernardino shooting is city’s 21st and 22nd homicides this year

“Nothing like this ever happens here,” said Jesse Alcantar, 68. “You know that saying ‘not in my neighborhood?’ Well … not anymore.”

Alcantar said he heard five shots, “like semi-automatic fire, bam bam bam!”

A woman near the scene, who said she feared the shooter could come after her, saw two cars, side-by-side, driving west on 29th Street and heard at least five rapidly fired shots.

At that point, the Honda veered off into a yard, hit the tree and a shed, she said.

With a view of the crime scene, Isabel Ruiz, 32, holding her 2-year-old son, said she was concerned for her safety. “I feel scared,” she said. “I called my husband and told him to come home (from work).

“We don’t see something like this around here,” said Ruiz, who lives less than a quarter-mile south where the shooting occurred.

• Video: Police spokeswoman discusses city’s latest homicides

The fatal shooting was the city’s second in the past 24 hours and marks the 21st and 22nd homicides in the city this year. There were 13 homicides in San Bernardino during the same time last year and 44 homicides in all 2015.

Just before 9:30 p.m. Tuesday, San Bernardino police were called to Blair Park, 1466 W. Marshall Blvd., to respond to a shooting, according to a police statement.

Officers found the wounded woman outside a white Mercedes sport utility vehicle yelling for help and a 47-year-old San Bernardino man dead inside the vehicle, officials said.

According to authorities, the two were drinking while parked in the SUV when someone approached them and began firing into the vehicle.

These recent shooting deaths come on the heels of a violent weekend where six people were wounded, two fatally, in five separate shootings.

Photo editor Rick Sforza contributed to this report.