(CNN) The Anti-Defamation League, a prominent Jewish advocacy group, slammed former Arkansas Gov. Mike Huckabee's comments Sunday that Obama is marching Israelis to "the door of the oven" by agreeing to the Iran nuclear deal.

Jonathan A. Greenblatt, the national director of the organization, issued a statement, calling the Republican 2016 hopeful's comments invoking the Holocaust "completely out of line and unacceptable."

"Israeli military and security officials have repeatedly said the Obama Administration has been as strong as any other American administration in keeping Israel secure," Greenblat writes.

"To hear Mr. Huckabee invoke the Holocaust when America is Israel's greatest ally and when Israel is a strong nation capable of defending itself is disheartening," Greenblat continues.

Huckabee, a Repbulican presidential candidate, used social media Sunday to stand by his comments, tweeting "Tell Congress to do their constitutional duty & reject the Obama-Kerry #IranDeal" as well as quotes from the Ayatollah Khamenei making threats against Israel.

Tell Congress to do their constitutional duty & reject the Obama-Kerry #IranDeal --> http://t.co/SaIyuq4w01 pic.twitter.com/2rFJgdDHhV — Gov. Mike Huckabee (@GovMikeHuckabee) July 26, 2015

Ayatollah Khamenei's Iranian Martyr Foundation rep: "We have manufactured missiles that allow us...to replace Israel...with a big holocaust" — Gov. Mike Huckabee (@GovMikeHuckabee) July 27, 2015

"It is the mission of the Islamic Republic of Iran to erase Israel from the map of the region." - Ayatollah Khamenei http://t.co/tMBfHPHZk2 — Gov. Mike Huckabee (@GovMikeHuckabee) July 27, 2015

"If they [Jews] all gather in Israel, it will save us the trouble of going after them worldwide." - Hassan Nasrallah, Hezbollah leader — Gov. Mike Huckabee (@GovMikeHuckabee) July 27, 2015

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