McConaughey plays a Texas electrician diagnosed with AIDS who began smuggling alternative drugs into the U.S. to help himself and other AIDS patients. His actions put him on a collision course with the F.D.A..

Garcia Bernal will play an effeminate member of the club and a fellow AIDS patient who meets Woodroof in the hospital. Craig Borten and Melisa Wallack adapted the script and shooting kicks off next month in New Orleans.