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Among the attendees of a DIY biology meeting in Seattle was Sandra Porter, who writes at her blog that the meeting focused on legal and safety concerns. The biggest legal problem, they think, would be to be sure that no one is making anything illegal -- and that the neighbors don't think it's a meth lab. As for safety, Porter says it varies depending on the organism being used and that yeast, though more difficult to work with, is probably the safest.