Fusion

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:query proteins and first shell of interactors

white nodes:second shell of interactors

Node Content

empty nodes:proteins of unknown 3D structure

filled nodes:some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Phatr48133

Predicted protein (360 aa)

Predicted Functional Partners:

SKT1

Succinyl-coenzyme A-3-oxo-acid coenzyme a-transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (511 aa)

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1

node2

node1 accession

node2 accession

node1 annotation

node2 annotation

score

FAO1

NRPS

Phatr55069

Phatr47104

Peroxisomal bifunctional enzyme

Non ribosomal peptide synthase

0.443

FAO1

Phatr29702

Phatr55069

Phatr29702

Peroxisomal bifunctional enzyme

Predicted protein

0.468

FAO1

Phatr31367

Phatr55069

Phatr31367

Peroxisomal bifunctional enzyme

Predicted protein

0.822

FAO1

Phatr35240

Phatr55069

Phatr35240

Peroxisomal bifunctional enzyme

Predicted protein

0.925

FAO1

Phatr48133

Phatr55069

Phatr48133

Peroxisomal bifunctional enzyme

Predicted protein

0.477

FAO1

Phatr49253

Phatr55069

Phatr49253

Peroxisomal bifunctional enzyme

Predicted protein

0.773

FAO1

SKT1

Phatr55069

Phatr23365

Peroxisomal bifunctional enzyme

Succinyl-coenzyme A-3-oxo-acid coenzyme a-transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate

0.826

NRPS

FAO1

Phatr47104

Phatr55069

Non ribosomal peptide synthase

Peroxisomal bifunctional enzyme

0.443

NRPS

Phatr29702

Phatr47104

Phatr29702

Non ribosomal peptide synthase

Predicted protein

0.440

NRPS

Phatr31367

Phatr47104

Phatr31367

Non ribosomal peptide synthase

Predicted protein

0.594

NRPS

Phatr35240

Phatr47104

Phatr35240

Non ribosomal peptide synthase

Predicted protein

0.443

NRPS

Phatr48133

Phatr47104

Phatr48133

Non ribosomal peptide synthase

Predicted protein

0.530

NRPS

Phatr49253

Phatr47104

Phatr49253

Non ribosomal peptide synthase

Predicted protein

0.506

Phatr10378

Phatr41807

Phatr10378

Phatr41807

Predicted protein

Predicted protein

0.996

Phatr10378

Phatr48133

Phatr10378

Phatr48133

Predicted protein

Predicted protein

0.651

Phatr29702

FAO1

Phatr29702

Phatr55069

Predicted protein

Peroxisomal bifunctional enzyme

0.468

Phatr29702

NRPS

Phatr29702

Phatr47104

Predicted protein

Non ribosomal peptide synthase

0.440

Phatr29702

Phatr31367

Phatr29702

Phatr31367

Predicted protein

Predicted protein

0.441

Phatr29702

Phatr35240

Phatr29702

Phatr35240

Predicted protein

Predicted protein

0.468

Phatr29702

Phatr48133

Phatr29702

Phatr48133

Predicted protein

Predicted protein

0.461

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Network Stats

Network Stats analysis is still ongoing, please wait ...

Functional enrichments in your networkNote: some enrichments may be expected here (why?)

Enrichment analysis is still ongoing, please wait ...

Statistical background

For the above enrichment analysis, the following statistical background is assumed: