There has been growing anger in Pakistan against US aerial attacks [EPA]
The attack on Saturday occurred in an area 35km west of the region's main town of Miranshah.
Up to 13 people have been killed in a suspected US drone attack in Pakistan's North Waziristan region near the Afghan border, security officials say.
The death toll is 13, including some foreigners, but information is very sketchy because it's a town which is very remote," one security official said on condition of anonymity.
Pakistani officials use the word "foreigner" to refer to suspected al-Qaeda and Taliban fighters, but the precise identities of the dead was not confirmed.
A local official said the compound that was hit belonged to Tariq Khan, who was described as a "facilitator of the Taliban".
Amir Shah, a resident of Waziristan, said drones were still flying over the area several hours after the attack.
'Safe haven'
With violence intensifying in Afghanistan, the US has launched more drone attacks on the Pakistani side of the border to destroy what it describes as "safe havens" for anti-government fighters.
The Pakistani government has protested to Washington against the drone strikes, saying they violated its territorial sovereignty.
But the US has kept up with its aerial attacks, accusing Islamabad of not doing enough to crack down on fighters who cross the border to attack US and Nato troops in Afghanistan.
Hundreds of Taliban and al-Qaeda fighters sought refuge in Pakistan's northwest tribal region after the US-led invasion of Afghanistan toppled the Taliban regime in late 2001.
Map of Waziristan, PakistanA suspected United States drone missile attack in northwestern Pakistan has left 13 people dead, local security officials say.

The strike hit a town in the tribal area of North Waziristan, near the Afghan border, an apparent stronghold of Al-Qaeda militants.

"Thirteen people were killed. Ten of them are militants and the identity of the other three — whether they are militants or civilians — is not yet confirmed," a local official told AFP, asking to remain anonymous. 

"The missile hit a house where some guests were staying. We have information that 13 people were killed including some guests," an intelligence official stated.

The apparent target was the home of Tariq Khan, a local Wazir tribesman, who has been described as a 'facilitator of the Taliban'.

Pakistan has repeatedly condemned the U.S. drone attacks. Just two days prior to this latest attack, foreign ministry spokesman Abdul Basit told a press briefing that "they are violations of our sovereignty and secondly they are counterproductive. They are not helpful in our efforts to win hearts and minds. So we cannot accept drone attacks," he said.

US special envoy Richard Holbrooke is scheduled to visit Pakistan next week and this issue will be discussed, according to Basit.

More than 35 suspected drone attacks have killed over 340 people since August last year.