Image copyright EPA Image caption Anti-government protesters in Caracas on Wednesday were met with tear gas and rubber bullets
Venezuela says it will withdraw from Organization of American States (OAS), accusing the Washington-based grouping of meddling in its internal affairs.
The government made the announcement after the OAS voted to hold an meeting of foreign ministers to discuss the spiralling crisis in Venezuela.
Neighbours have expressed concern at mounting unrest in the country.
Violent protests against the government continued in the capital Caracas on Wednesday. One protester was killed.
He was hit by a tear gas canister during clashes with police.
Nearly 30 people have been killed since the wave of protests against President Nicolas Maduro began last month.
Image copyright EPA Image caption The security forces had to defend themselves against stone throwers and petrol bombs
Image copyright EPA Image caption Lilian Tintori (above), the wife of opposition leader Leopoldo Lopez, participated in Wednesday's protests
Image copyright Reuters Image caption The opposition wants early elections and the release of politicians arrested since the president took office in 2013
The Venezuelan government has accused the US trying to undermine Mr Maduro's Socialist Party.
On Wednesday, Ms Rodriguez said the protests were part of an organised effort to defeat Venezuela's Bolivarian Revolution.
"Tomorrow [Thursday] we will present a letter of complaint to the OAS and we will begin a process that will take 24 months," she announced in a televised statement.
Image copyright AFP Image caption Venezuelan Foreign Minister Delcy Rodriguez (right) and OAS Secretary General Luis Almagro (left) have rarely seen eye to eye
BBC Latin America correspondent Will Grant says the move comes as little surprise.
Tensions in the organisation - and among Venezuela's neighbours - have grown over what is seen by several member states as the government's disregard for democracy amid mounting unrest.
Ms Rodriguez accused the OAS of having double standards by concentrating on what was happening in her country while ignoring alleged democracy violations in Brazil.
President Maduro has often strongly denounced the grouping.
Economic meltdown
Venezuela, an oil-rich nation, is going through a serious economic crisis.
Inflation is expected to reach 700% this year, according to the International Monetary Fund, and there is shortage of many basic goods, including medicines.
The opposition blames the socialist policies of Mr Maduro and his predecessor, Hugo Chavez, for the economic meltdown.
But the government says the country is suffering from the effects of economic sabotage carried out by the business elite.
Image copyright Reuters Image caption Some of the protesters on Wednesday used catapults to target the security forces
Image copyright AFP Image caption Government supporters also marching through the streets of Caracas on Wednesday
The latest series of protests began after the Supreme Court took over powers from the opposition-controlled National Assembly on 29 March.
It reversed its decision three days later, but opposition protesters were already on the streets in large numbers, seizing the opportunity to strike against Mr Maduro's government.
The opposition wants early elections and the release of politicians arrested since the president took office in 2013.
Thousands of his supporters held a counter-rally in Caracas on Wednesday.
La Ministra de Relaciones Exteriores de  anunció que su país se retirará de la , OEA, poco después de que 19 países del grupo continental acordaran convocar a una reunión de cancilleres para tratar la situación de crisis en la nación .

En declaraciones en la , Rodríguez dijo que el proceso para abandonar la OEA, que tarda 24 meses, se iniciará el jueves con una carta de denuncia del presidente  a la organización.

La canciller señaló que la nación no participará más en "ninguna actividad de ningún evento donde se pretenda posicionar el intervencionismo y el injerencismo de este grupo de países que solo buscan perturbar la estabilidad y la paz", en Venezuela.

La resolución para convocar a consulta a los cancilleres de la OEA fue aprobada por , , , , , , , , , , , , , ,  y .

La ministra Rodríguez acusó a esos países de ser "mercenarios de la política para coartar el derecho al futuro del pueblo de Venezuela, para coartar y afectar el derecho a la patria, el derecho a vivir tranquilamente".

La diplomática venezolana explicó que la retirada de su nación de la OEA "tiene que ver con la dignidad de nuestro pueblo, con la doctrina bolivariana que promueve el no intervencionismo, que defiende la igualdad soberana de los estados, el multilateralismo en igualdad jurídica".

Rodríguez pronosticó el fracaso de lo que llamó, las "pretensiones de aislar a Venezuela " bajo lo que denunció como la implementación de un "guión preestablecido" como ocurrió con  en 1962, y que determinó la salida de esta nación del organismo continental.

La jefa de la diplomacia venezolana acusó a los países que votaron para aprobar la resolución de la OEA el miércoles, de ser un "cónclave de gobiernos mercenarios" que han estimulado la ola de violencia en Venezuela en el último mes, en el que decenas de protestas antigubernamentales han dejado al menos 29 muertos, unos 500 heridos y más de 1.000 detenidos.

Rodríguez advirtió que la decisión en la OEA hará que continúen las protestas porque "los violentos...se sienten apoyados, porque creen que cuentan con el apoyo de la comunidad internacional".