Does Botulinum toxin cause botulism?
Botulism
Botulism is a rare and potentially fatal illness caused by a toxin produced by the bacterium Clostridium botulinum.[1] The disease begins with weakness, blurred vision, feeling tired, and trouble speaking.[1] This may then be followed by weakness of the arms, chest muscles, and legs.[1] Vomiting, swelling of the abdomen, and diarrhea may also occur.[1] The disease does not usually affect consciousness or cause a fever.[1]
Botulinum toxin
The seven toxin types (A-G) have different tertiary structures and sequence differences.[36][37] While the different toxin types all target members of the SNARE family, different toxin types target different SNARE family members.[35] The A, B, and E serotypes cause human botulism, with the activities of types A and B enduring longest in vivo (from several weeks to months).[36]