When was sjögren syndrome first identified?
Sjögren syndrome
The disease was described in 1933 by Henrik Sjögren, after whom it is named; however, a number of earlier descriptions of people with the symptoms exist.[3] Between 0.2% and 1.2% of the population are affected, with half having the primary form and half the secondary form.[7] Females are affected about ten times as often as males and it commonly begins in middle age;[2][3] however, anyone can be affected.[2] Among those without other autoimmune disorders, life expectancy is unchanged.[6]
Pancreatic cancer
Regarding the recognition of PanNETs, the possibility of cancer of the islet cells was initially suggested in 1888. The first case of hyperinsulinism due to a tumor of this type was reported in 1927. Recognition of a non-insulin-secreting type of PanNET is generally ascribed to the American surgeons, R. M. Zollinger and E. H. Ellison, who gave their names to Zollinger–Ellison syndrome, after postulating the existence of a gastrin-secreting pancreatic tumor in a report of two cases of unusually severe peptic ulcers published in 1955. In 2010, the WHO recommended that PanNETs be referred to as "neuroendocrine" rather than "endocrine" tumors.