Family members, in turn, may feel angry — with the doctors for not detecting the problem sooner, with themselves for passing on a genetic defect, with the patient for not having looked after himself properly, with Satan the Devil for causing such suffering, or even with God, feeling that he is to blame for the illness.
Pereliikmed võivad aga omakorda hakata tundma viha arstide vastu, et need haigust varem ei avastanud, enda vastu, et lapsed neilt selle geneetilise defekti pärisid, haige vastu, et ta ei kandnud enda eest piisavalt hoolt, Kurat - Saatana vastu, et ta valmistab selliseid kannatusi, või isegi Jumala vastu, et tema on selles haiguses süüdi.