When that marriage was no longer politically expedient, a pretext was found to annul it, and Lucrezia was wed to a member of a rival dynasty, Alfonso of Aragon.
Kui nende abielu polnud enam poliitiliselt kasulik, leiti ettekääne selle tühistamiseks ja Lucrezia laulatati rivaalitseva dünastia liikme Aragóni Alfonsoga.