The most serious form is called diffuse or systemic and is characterized by rapid development of a thickening of the skin, beginning with the hands and face and extending to the arms and trunk.
Raskeimat vormi nimetatakse süsteemseks sklerodermiaks, millele on iseloomulik naha kiire paksenemine, mis algab kätest ja näost ning laieneb üle käsivarte ja rindkere.