Although mastic trees grow all along the Mediterranean Coast, since about 50 C.E., the production of mastic has been confined almost exclusively to Chios.
Kuigi mastiksipistaatsiaid kasvab kõikjal piki Vahemere rannikut, toodetakse mastiksit alates umbes meie ajaarvamise 50. aastast enamasti vaid Chiose saarel.