The researchers, however, point out that the effects of hopelessness often vary among individuals, depending on such factors as childhood experiences, depression, cultural background, and economic security.
Teadlased aga juhivad tähelepanu ka sellele, et lootusetus mõjub inimestele sageli eri moodi, olenevalt lapsepõlvekogemustest, depressioonist, kultuurilisest taustast ja majanduslikust kindlustatusest.