His uncle Alfonso de Borgia, bishop of Valencia, guided his nephew’s education and saw to it that while still in his teens, Rodrigo was endowed with ecclesiastical benefices (ecclesiastical offices with revenue attached). At age 18, under the protection of Alfonso, by now a cardinal, Rodrigo moved to Italy, where he studied law.
Tema onu, Valencia piiskop Alfonso de Borgia hoolitses oma õepoja koolituse eest ja kindlustas, et veel teismeeas Rodrigo saaks kiriklikke benefiitse (tasustatud kiriklikke ametikohti). 18 - aastaselt kolis Rodrigo Alfonso soosikuna, kes oli sel ajal juba kardinal, Itaaliasse õigusteadust õppima.