Payette visited the space station again in 2009 as a mission specialist aboard Space Shuttle Endeavour during mission STS-127 from July 15 to 31, 2009, and was the flight engineer and lead robotic operator during the mission.
Payettová navštívila stanicu znovu v roku 2009 ako letová špecialistka na palube raketoplánu Endeavour počas misie STS-127 prebiehajúcej 15. až 31. jôla 2009, bola letovou inžinierkou a hlavnou operátorkou robotov počas tejto misie.