Artemisia was once thought to have died in 1652/1653; however, recent evidence has shown that she was still accepting commissions in 1654, although she was increasingly dependent upon her assistant, Onofrio Palumbo.
Obvykle sa uvádza, že zomrela v roku 1653, v poslednom čase sa však objavili úvahy, že žila ešte v roku 1654, a dokonca prijímala zákazky, napriek tomu, že bola stále viac závislá na svojom pomocníkovi Onofriovi Palumbovi.