Chronic impairment of bile flow due to blockage and dysfunctional bile transport (cholestasis) causes progressive biliary fibrosis and ultimately biliary cirrhosis and liver failure.
Chronické poškodenie prúdenia žlče v dôsledku blokácie a dysfunkcie transportu žlče (cholestáza) spôsobuje progresívnu biliárna fibrózu a nakoniec biliárnu cirhózu a zlyhanie pečene .