The role of AEP in immunity is not clear, but it seems that it is connected with checkpoint inhibitors such as PD-1, which downregulates AEP which is key to shifting the balance between cancer fighting cells and regulatory T cells.
Úloha AEP v imunite nie je jasná alebo vyzerá to tak, že je spojená s checkpointovými inhibítormi ako PD-1, ktorý znižuje expresiu AEP, čo je nevyhnutné pre posunutie rovnováhy medzi bojom proti rakovine a regulačnými T-bunkami.