The first parts of the Palace were built between 1251 and 1275, during the flourishing period of the Republican history of Genoa, while the Torre Grimaldina (also named "Torre del Popolo" - Tower of the People) was completed in 1539.
Prvé časti paláca boli postavené medzi rokmi 1251 and 1275, počas rozkvetu Janovskej republiky, kým Torre Grimaldina (známa aj ako „Torre del Popolo“) bola dokončená v roku 1539.