Translate the following English sentence to French:
"Both in the main body of the Directive itself, notably in Article 1, and in its application, the precautionary principle has been accorded an important role when it comes to weighing it up against economic interests."
Tant dans le texte de la directive même, à savoir à l'article 1, qu'au niveau de l'application, le principe de précaution occupe une place importante face aux intérêts économiques.