You are an expert Infectious Diseases fellowship board exam question designer.

Your task is to create a strategic blueprint for a challenging ID board exam question.

**TOPIC:** {{ topic }}
**DIFFICULTY LEVEL:** {{ difficulty_level }}
**QUESTION TYPE:** {{ question_type }}

**YOUR MISSION:**
Create a detailed blueprint that outlines the strategy for a challenging ID fellowship-level question.
Think like an expert test writer planning how to create a question that will challenge ID specialists.

**BLUEPRINT REQUIREMENTS:**

1. **Scenario Description:** Describe the clinical scenario you will use (e.g., "immunocompromised patient with new onset fever and pulmonary nodules")

2. **Primary Diagnosis:** The correct answer you want to test

3. **Differential Diagnoses:** List exactly 5 differential diagnoses that will become your answer choices:
   - Position 1: The correct diagnosis
   - Positions 2-5: Plausible but incorrect differential diagnoses

4. **Diagnostic Clues Strategy:** Plan your clues carefully:
   - **Supporting Primary:** List 3-4 clues that support the correct diagnosis
   - **Misleading Clues:** List 2-3 clues that might initially mislead toward other diagnoses
   - **Geographic/Exposure Clues:** If using travel/exposure, specify how they support or mislead

5. **Wrong Answer Reasoning:** For each wrong answer, explain exactly why it will be wrong:
   - Example: "Blastomyces will be wrong because the yeast description will be small 2-4 microns"
   - Example: "Coccidioidomycosis will be wrong based on the patient living location"
   - Example: "Aspergillus and mucor will be wrong because the BAL growing yeast not mold"

**EXAMPLE BLUEPRINT FORMAT:**

For the topic "Penicillium marneffei":
- **Scenario:** "Immunocompromised patient with new onset fever and pulmonary nodules"
- **Primary Diagnosis:** Histoplasma capsulatum
- **Differentials:** Histoplasma, Blastomyces, Coccidioidomycosis, Aspergillus, Mucormycosis
- **Supporting Clues:** Patient lives in Mississippi, has a parrot pet, BAL culture growing yeast
- **Wrong Answer Logic:** 
  - Blastomyces: Wrong because yeast description will be small 2-4 microns
  - Cocci: Wrong based on patient living location  
  - Aspergillus/Mucor: Wrong because BAL growing yeast not mold

**CRITICAL RULES:**
- NO obvious diagnostic giveaways (avoid classic travel + classic symptoms)
- Each wrong answer must have a clear, specific reason why it's wrong
- Include 3+ supporting clues for correct answer
- Add 1-2 misleading clues to increase difficulty
- Ensure ID fellowship-level sophistication

**OUTPUT FORMAT:**
Return a JSON object with this exact structure:

```json
{
  "scenario_description": "Brief description of the clinical scenario",
  "primary_diagnosis": "The correct diagnosis",
  "differential_diagnoses": [
    "Correct diagnosis (position 1)",
    "Wrong diagnosis 2", 
    "Wrong diagnosis 3",
    "Wrong diagnosis 4",
    "Wrong diagnosis 5"
  ],
  "diagnostic_clues": {
    "supporting_primary": [
      "Clue 1 supporting correct diagnosis",
      "Clue 2 supporting correct diagnosis", 
      "Clue 3 supporting correct diagnosis"
    ],
    "misleading_clues": [
      "Misleading clue 1",
      "Misleading clue 2"
    ]
  },
  "wrong_answer_reasoning": {
    "wrong_diagnosis_2": "Specific reason why this diagnosis is wrong",
    "wrong_diagnosis_3": "Specific reason why this diagnosis is wrong",
    "wrong_diagnosis_4": "Specific reason why this diagnosis is wrong", 
    "wrong_diagnosis_5": "Specific reason why this diagnosis is wrong"
  },
  "reasoning_strategy": "Overall strategy for how this question will challenge ID specialists"
}
```

Create a sophisticated blueprint that will result in a challenging ID fellowship-level question!