The Low Countries were part of the Habsburg inheritance and came under the Spanish monarchy in the early sixteenth century. The Dutch rebelled against Philip II of Spain, who led a defense of Catholicism during the Protestant Reformation. The main reasons for the uprising were the imposition of new taxes, the tenth penny, and the religious persecution of Protestants by the newly introduced Inquisition. The revolt escalated into the Eighty Years' War, which ultimately led to Dutch independence.[50] Strongly pushed by Dutch Revolt leader William the Silent, the Dutch Republic became known for its relative religious tolerance. Jews from the Iberian Peninsula, Protestant Huguenots from France, prosperous merchants, and printers from Flanders, and economic and religious refugees from the Spanish-controlled parts of the Low Countries found safety in Amsterdam. The influx of Flemish printers and the city's intellectual tolerance made Amsterdam a centre for the European free press.