<p>I have microRNA (miRNA) expression data in RPM. I would like to do differential gene expression between two groups.</p>
<p>How can I do this?</p>
<p>I have considered edgeR and DESeq2 in R, but it looks like they require counts and I cannot use RPM in these. Or can I convert RPM to counts?</p>
<p>Can anyone help?</p>

CC BY-SA 4.0
2021-08-24T03:37:16.953Z
Thank you. I will try that.
Sylvia Rodriguez
<r><differential-expression><deseq2><gene-expression><edger>
Differential miRNA expression using RPM
# Differential miRNA expression using RPM

(Asked by: username_0 on 2021-08-23)

I have microRNA (miRNA) expression data in RPM. I would like to do differential gene expression between two groups.

How can I do this?

I have considered edgeR and DESeq2 in R, but it looks like they require counts and I cannot use RPM in these. Or can I convert RPM to counts?

Can anyone help?

**Tags:** r, differential-expression, deseq2, gene-expression, edger
> **Comments:**
> **username_0**: Thank you. I will try that.  

---

## 0 answers

