<p>I would suggest looking into <a href="https://www.gencodegenes.org/human/" rel="nofollow noreferrer">GFF3 annotations</a> of the human genome.</p>
<p>If what you want is <em>protein domain annotations</em>, you may be more interested in the <a href="https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/" rel="nofollow noreferrer">UniProt database</a> which does seem to include <a href="https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/UP000000589_10090_beds/" rel="nofollow noreferrer">genome annotation tracks</a> for different protein functional regions.</p>
<p>I am unclear if uniprot directly has the gene names but this would be trivial to generate with a <code>bedtools intersect</code> operation.</p>

CC BY-SA 4.0
2024-02-01T21:06:40.457Z
2024-02-01T21:06:40.457Z
Maximilian Press
<p>I'm visualizing where mutations occur in a gene, and would like to add functional domains to the plots.</p>
<p>I have some trouble locating sources to download data on functional domains.</p>
<p>The dataset should contain:</p>
<ul>
<li>Functional domain name</li>
<li>Start position in gene</li>
<li>End position in gene</li>
<li>Gene symbol name</li>
</ul>
<p>Any tips kindly appreciated!</p>

CC BY-SA 4.0
2024-01-08T15:31:27.507Z
Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.
Community
<genome><database><data-download><public-dataset><functional-annotation>
Where can you download functional domain labels of the human genome?
# Where can you download functional domain labels of the human genome?

(Asked by: username_0 on 2024-01-08)

I'm visualizing where mutations occur in a gene, and would like to add functional domains to the plots.

I have some trouble locating sources to download data on functional domains.

The dataset should contain:

* Functional domain name
* Start position in gene
* End position in gene
* Gene symbol name

Any tips kindly appreciated!

**Tags:** genome, database, data-download, public-dataset, functional-annotation
> **Comments:**
> **username_1**: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.  

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## 1 answers

### Answer by username_2 on 2024-02-01. Score: 0

I would suggest looking into [GFF3 annotations](https://www.gencodegenes.org/human/) of the human genome.

If what you want is *protein domain annotations*, you may be more interested in the [UniProt database](https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/) which does seem to include [genome annotation tracks](https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/UP000000589_10090_beds/) for different protein functional regions.

I am unclear if uniprot directly has the gene names but this would be trivial to generate with a `bedtools intersect` operation.


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