<p>The basemean is described as the &quot;mean of normalized counts of all samples&quot;. My question is, how would we interpret differences in basemean between genes, pertaining to reliability and such? For example, if two genes that have similar p-values and l2fchanges, but one has a much higher basemean, would that gene's data be more dependable?</p>
<p>Sorry if this is a trivial question!</p>

<deseq2>
Use of "baseMean" in DeSEQ2
# Use of "baseMean" in DeSEQ2

(Asked by: username_0 on 2021-12-30)

The basemean is described as the "mean of normalized counts of all samples". My question is, how would we interpret differences in basemean between genes, pertaining to reliability and such? For example, if two genes that have similar p-values and l2fchanges, but one has a much higher basemean, would that gene's data be more dependable?

Sorry if this is a trivial question!

**Tags:** deseq2

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