<p>If you're building a tree of different species, it's probably better to use protein sequences. A common resource is <a href="https://www.uniprot.org/" rel="nofollow noreferrer">Uniprot</a>.</p>
<p>If you still want DNA sequences you can turn to <a href="https://www.ncbi.nlm.nih.gov/nuccore" rel="nofollow noreferrer">NCBI Nucleotide</a>.</p>
<p>Some examples that give decent trees: p53, TOP1, HBA.</p>
<p>A common way to construct a phylogenetic tree is to start with a <a href="https://en.wikipedia.org/wiki/Multiple_sequence_alignment" rel="nofollow noreferrer">multiple sequence alignment (MSA)</a>.</p>

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2021-02-25T19:53:05.400Z
2021-02-25T19:53:05.400Z
Michael
<p>As a way to exemplify how the hierarchical clustering of particular DNA sequences can be used to derive phylogenetic trees, I'm looking for a (even very small) dataset of the same genes (or other biological sequences) from different organisms (for example animals where the evolutionary tree is known). Do you have any pointers?</p>
<p>Thanks in advance</p>

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2021-02-27T18:35:32.230Z
I don't understand what the problem is. If you just want a bunch of sequences of homologous genes from different organisms, it is very easy to get them from places like NCBI or Ensembl. What is giving you trouble here? Do you need help using the standard databases, or do you need help in selecting the genes of interest? Could you please [edit] your question and explain what you are stuck on?
terdon
<gene><phylogeny><phylogenetics><clustering>
Dataset showing evolution of gene
# Dataset showing evolution of gene

(Asked by: username_0 on 2021-02-25)

As a way to exemplify how the hierarchical clustering of particular DNA sequences can be used to derive phylogenetic trees, I'm looking for a (even very small) dataset of the same genes (or other biological sequences) from different organisms (for example animals where the evolutionary tree is known). Do you have any pointers?

Thanks in advance

**Tags:** gene, phylogeny, phylogenetics, clustering
> **Comments:**
> **username_1**: I don't understand what the problem is. If you just want a bunch of sequences of homologous genes from different organisms, it is very easy to get them from places like NCBI or Ensembl. What is giving you trouble here? Do you need help using the standard databases, or do you need help in selecting the genes of interest? Could you please [edit] your question and explain what you are stuck on?  

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## 1 answers

### Answer by username_2 on 2021-02-25. Score: 0 | Accepted answer

If you're building a tree of different species, it's probably better to use protein sequences. A common resource is [Uniprot](https://www.uniprot.org/).

If you still want DNA sequences you can turn to [NCBI Nucleotide](https://www.ncbi.nlm.nih.gov/nuccore).

Some examples that give decent trees: p53, TOP1, HBA.

A common way to construct a phylogenetic tree is to start with a [multiple sequence alignment (MSA)](https://en.wikipedia.org/wiki/Multiple_sequence_alignment).


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