<p>They are two very different things. Your genome is a large section of about 3 billion DNA nucleotide bases. It has no concept of exon and introns.</p>

<p>Transcriptome is a study of <a href="https://en.wikipedia.org/wiki/Transcription_(biology)" rel="noreferrer">transcriptions</a>. You have introns and exons. We can now talk about alternative splicing and gene expression.</p>

<p>You can think your genome is like a cooking recipe. While it's good to have a good recipe, you can't do much if you don't use it for cooking. </p>

CC BY-SA 4.0
2019-04-04T08:02:05.130Z
I like to compare the genome with the cookbook, the transcriptome with your shopping lists, the proteome with your groceries.
Wouter De Coster
CC BY-SA 4.0
2022-04-08T18:32:12.787Z
wouldn't the proteome be the cooked food?
CelineDion
CC BY-SA 3.0
2017-05-17T05:13:07.323Z
2017-05-17T05:13:07.323Z
SmallChess
<p>In brief, the  “genome”  is the collection of all  DNA  present  in  the  nucleus  and  the  mitochondria of a  somatic  cell. The initial product of genome expression is the “transcriptome”, a collection of RNA molecules derived from those genes.</p>

CC BY-SA 3.0
2017-06-02T03:26:13.117Z
This is a good concise answer.
EMiller
CC BY-SA 3.0
2017-05-17T05:37:31.687Z
If you want to learn more about relationships between these terms, see this [Wikipedia page](https://en.wikipedia.org/wiki/Central_dogma_of_molecular_biology).
CloudyGloudy
CC BY-SA 3.0
2017-05-17T04:52:48.293Z
2017-05-18T00:01:35.137Z
2017-05-18T00:01:35.137Z
Prradep
<p>I have a computer engineering background, not biology.</p>

<p>I started working on a bioinformatics project recently, which involves <em>de-novo</em> assembly. I came to know the terms <code>Transcriptome</code> and <code>Genome</code>, but I cannot identify the difference between these two.</p>

<p>I know a transcriptome is the set of all messenger RNA molecules in a cell, but am not sure how this is different from a genome.</p>

CC BY-SA 3.0
2017-05-17T08:04:24.967Z
What information have you researched ? Did Wikipedia pages of Transcriptome and Genome helped you? If not where they didn't help you
llrs
CC BY-SA 3.0
2017-05-17T08:04:59.150Z
This is a rather basic question and I don't think it's a good one for the site, in the message from stack exchange it says "if you ask beginner questions, survey questions, or social-conversation questions, experts and pros will not be interested"
Chris_Rands
CC BY-SA 3.0
2017-05-17T08:27:14.107Z
You can vote to close the question
llrs
<genome><transcriptome>
What is the difference between a transcriptome and a genome?
# What is the difference between a transcriptome and a genome?

(Asked by: username_0 on 2017-05-17)

I have a computer engineering background, not biology.

I started working on a bioinformatics project recently, which involves *de-novo* assembly. I came to know the terms `Transcriptome` and `Genome`, but I cannot identify the difference between these two.

I know a transcriptome is the set of all messenger RNA molecules in a cell, but am not sure how this is different from a genome.

**Tags:** genome, transcriptome
> **Comments:**
> **username_1**: What information have you researched ? Did Wikipedia pages of Transcriptome and Genome helped you? If not where they didn't help you  
> **username_2**: This is a rather basic question and I don't think it's a good one for the site, in the message from stack exchange it says "if you ask beginner questions, survey questions, or social-conversation questions, experts and pros will not be interested"  
> **username_1**: You can vote to close the question  

---

## 2 answers

### Answer by username_6 on 2017-05-17. Score: 18 | Accepted answer

In brief, the “genome” is the collection of all DNA present in the nucleus and the mitochondria of a somatic cell. The initial product of genome expression is the “transcriptome”, a collection of RNA molecules derived from those genes.

> **Comments:**
> **username_8**: If you want to learn more about relationships between these terms, see this [Wikipedia page](https://en.wikipedia.org/wiki/Central_dogma_of_molecular_biology).  
> **username_7**: This is a good concise answer.  

---

### Answer by username_3 on 2017-05-17. Score: 5

They are two very different things. Your genome is a large section of about 3 billion DNA nucleotide bases. It has no concept of exon and introns.

Transcriptome is a study of [transcriptions](https://en.wikipedia.org/wiki/Transcription_(biology)). You have introns and exons. We can now talk about alternative splicing and gene expression.

You can think your genome is like a cooking recipe. While it's good to have a good recipe, you can't do much if you don't use it for cooking.

> **Comments:**
> **username_4**: I like to compare the genome with the cookbook, the transcriptome with your shopping lists, the proteome with your groceries.  
> **username_5**: wouldn't the proteome be the cooked food?  

---

