<p>Maybe can try the ComBat to remove the batch effect</p>

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2021-02-18T07:21:30.483Z
2021-02-18T07:21:30.483Z
LeadingBiology
<p><em>This question has also been asked on <a href="https://www.biostars.org/p/491078/" rel="nofollow noreferrer">Biostars</a></em></p>
<p>I have a challenge in analyzing GSE34941( It has 4 platforms) according to the expression of a specific gene in R. First, which is the best way to group my patients according to the expression of a gene to high- and low-expression? Second, which is the best way to remove the batch effect of multi-platform analysis here?</p>
<p>I really appreciate any help you can provide.</p>

<r><microarray><geo>
multi--platform GEO analysis based in expression of single gene
# multi--platform GEO analysis based in expression of single gene

(Asked by: username_0 on 2021-02-15)

*This question has also been asked on [Biostars](https://www.biostars.org/p/491078/)*

I have a challenge in analyzing GSE34941( It has 4 platforms) according to the expression of a specific gene in R. First, which is the best way to group my patients according to the expression of a gene to high- and low-expression? Second, which is the best way to remove the batch effect of multi-platform analysis here?

I really appreciate any help you can provide.

**Tags:** r, microarray, geo

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## 1 answers

### Answer by username_1 on 2021-02-18. Score: -1

Maybe can try the ComBat to remove the batch effect


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