<p>Most <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=qtl+mapping+gwas" rel="nofollow noreferrer">papers</a> that I've looked at distinguish between looking for genotype/trait associations in mapping populations created by experimental crosses (QTL mapping) and looking for genotype/trait associations in populations of unrelated individuals (GWAS). No distinction is made between susceptibility to disease (often referred to as a case-control GWAS) and continuous traits (all of the big studies on genetic associations with <a href="https://www.nature.com/articles/ng.3097" rel="nofollow noreferrer">height</a> use the term GWAS, for example).</p>

<p>Many of the papers in my first link use both methods, so you can take a look at them to get an idea of the advantages and limitations of each.</p>

CC BY-SA 3.0
2017-12-11T15:24:31.860Z
2017-12-11T15:24:31.860Z
heathobrien
<p>What are the differences between the two methods? </p>

<p>What advantages does one have over the other, and what are their limitations relative to one another?</p>

CC BY-SA 3.0
2017-12-09T19:46:13.647Z
This question is too broad, and is prone to subjective answers that aren't very helpful. Please try to narrow your question, preferably thinking about a specific task that you would like to carry out.
gringer
<genomics><gwas>
What are the differences between GWAS and QTL mapping?
# What are the differences between GWAS and QTL mapping?

(Asked by: username_0 on 2017-12-09)

What are the differences between the two methods?

What advantages does one have over the other, and what are their limitations relative to one another?

**Tags:** genomics, gwas
> **Comments:**
> **username_1**: This question is too broad, and is prone to subjective answers that aren't very helpful. Please try to narrow your question, preferably thinking about a specific task that you would like to carry out.  

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## 1 answers

### Answer by username_2 on 2017-12-11. Score: 2

Most [papers](https://www.ncbi.nlm.nih.gov/pubmed/?term=qtl+mapping+gwas) that I've looked at distinguish between looking for genotype/trait associations in mapping populations created by experimental crosses (QTL mapping) and looking for genotype/trait associations in populations of unrelated individuals (GWAS). No distinction is made between susceptibility to disease (often referred to as a case-control GWAS) and continuous traits (all of the big studies on genetic associations with [height](https://www.nature.com/articles/ng.3097) use the term GWAS, for example).

Many of the papers in my first link use both methods, so you can take a look at them to get an idea of the advantages and limitations of each.


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