<p>I am trying to build a model for variant calling,but I am a bit confused how to pre-process the reads that has insertion and deletion and align them with reference?</p>
<p>Should I add something to the location of insertion or deletion to reference or should I just delete from read?</p>

CC BY-SA 4.0
2022-05-23T15:34:57.477Z
Can you provide some reference for why you think preprocessing is necessary?
Maximilian Press
CC BY-SA 4.0
2022-05-23T17:56:41.093Z
Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.
Community
CC BY-SA 4.0
2022-05-24T03:59:19.613Z
Are you building a model specifically for deep variant, or trying to create your own model via a different algorithm?
gringer
<variant-calling>
How deep variant and others preprocessed insertion and deletion for extracting candidate variant?
# How deep variant and others preprocessed insertion and deletion for extracting candidate variant?

(Asked by: username_0 on 2022-05-23)

I am trying to build a model for variant calling,but I am a bit confused how to pre-process the reads that has insertion and deletion and align them with reference?

Should I add something to the location of insertion or deletion to reference or should I just delete from read?

**Tags:** variant-calling
> **Comments:**
> **username_1**: Can you provide some reference for why you think preprocessing is necessary?  
> **username_2**: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.  
> **username_3**: Are you building a model specifically for deep variant, or trying to create your own model via a different algorithm?  

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## 0 answers

