<p><a href="https://www.cellphonedb.org" rel="nofollow noreferrer">CellPhoneDB</a> is a publicly available repository of <em>curated</em> receptors, ligands and their interactions.</p>

<p>The interactions can be searched or downloaded.</p>

CC BY-SA 4.0
2018-10-22T11:05:31.313Z
2018-10-22T11:05:31.313Z
Peter
<p>Have you tried <a href="https://string-db.org/cgi/input.pl?sessionId=QLEnNyQMCbBE&amp;input_page_show_search=on" rel="nofollow noreferrer">STRING</a>? </p>

<p>It's a publicly available protein-protein interaction database, so it won't be a complete picture. </p>

<p><a href="https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/" rel="nofollow noreferrer">Ingenuity Pathways Analysis (IPA)</a> is really nice but is a paid service. Ask your institution if they have a license for one. </p>

CC BY-SA 4.0
2018-10-22T13:43:17.997Z
Can you include a link to IPA please.
Bioathlete
CC BY-SA 4.0
2018-10-22T17:47:29.283Z
https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/
Yuka Takemon
CC BY-SA 4.0
2018-10-22T12:21:14.633Z
2018-10-22T14:20:02.333Z
2018-10-22T14:20:02.333Z
Yuka Takemon
<p><a href="http://tcm.zju.edu.cn/celltalkdb/search.php" rel="nofollow noreferrer">CellTalkDB</a> is another option for a searchable ligand-receptor database. According to the webpage it is curated from other databases and the literature. Details are available in the <a href="https://academic.oup.com/bib/advance-article-abstract/doi/10.1093/bib/bbaa269/5955941" rel="nofollow noreferrer">publication</a>.</p>

CC BY-SA 4.0
2020-12-09T02:23:26.690Z
2020-12-09T02:23:26.690Z
Tapper
<p>How can I find ligands of receptors (or <em>vice versa</em>)?</p>

<p>For example, I want to find the receptors of IL-8 (CXCL8).</p>

<database><public-databases><protein-protein-interaction>
Receptor-ligand database
# Receptor-ligand database

(Asked by: username_0 on 2018-10-22)

How can I find ligands of receptors (or *vice versa*)?

For example, I want to find the receptors of IL-8 (CXCL8).

**Tags:** database, public-databases, protein-protein-interaction

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## 3 answers

### Answer by username_0 on 2018-10-22. Score: 3 | Accepted answer

[CellPhoneDB](https://www.cellphonedb.org) is a publicly available repository of *curated* receptors, ligands and their interactions.

The interactions can be searched or downloaded.


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### Answer by username_1 on 2018-10-22. Score: 2

Have you tried [STRING](https://string-db.org/cgi/input.pl?sessionId=QLEnNyQMCbBE&input_page_show_search=on)?

It's a publicly available protein-protein interaction database, so it won't be a complete picture.

[Ingenuity Pathways Analysis (IPA)](https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/) is really nice but is a paid service. Ask your institution if they have a license for one.

> **Comments:**
> **username_2**: Can you include a link to IPA please.  
> **username_1**: https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/  

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### Answer by username_3 on 2020-12-09. Score: 0

[CellTalkDB](http://tcm.zju.edu.cn/celltalkdb/search.php) is another option for a searchable ligand-receptor database. According to the webpage it is curated from other databases and the literature. Details are available in the [publication](https://academic.oup.com/bib/advance-article-abstract/doi/10.1093/bib/bbaa269/5955941).


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