<p>I assume by &quot;blood contamination&quot; you are interested in tumor purity and immune cell infiltration. For that you can use a deconvolution tool for bulk RNA-seq like <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895181/" rel="noreferrer">CIBERSORT</a> or <a href="https://icbi.i-med.ac.at/software/quantiseq/doc/" rel="noreferrer">quanTIseq</a></p>

CC BY-SA 4.0
2023-01-31T08:22:49.797Z
2023-01-31T08:22:49.797Z
Chris_Rands
<p>I have tumor rna seq samples. I want to find out percentage of blood contamination within these samples. What is the best possible way to find % of blood contamination within the rna seq samples?</p>

<rna-seq>
blood contamination rna seq
# blood contamination rna seq

(Asked by: username_0 on 2023-01-31)

I have tumor rna seq samples. I want to find out percentage of blood contamination within these samples. What is the best possible way to find % of blood contamination within the rna seq samples?

**Tags:** rna-seq

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## 1 answers

### Answer by username_1 on 2023-01-31. Score: 5

I assume by "blood contamination" you are interested in tumor purity and immune cell infiltration. For that you can use a deconvolution tool for bulk RNA-seq like [CIBERSORT](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895181/) or [quanTIseq](https://icbi.i-med.ac.at/software/quantiseq/doc/)


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