<p>Yes, they are base pair positions</p>

CC BY-SA 4.0
2021-11-23T14:24:56.377Z
2021-11-23T14:24:56.377Z
Emily_Ensembl
<p>HG19 refers to the <em>build</em> used as the reference genome. To extend on what @Emily_Ensembl said, base pair positions may change between different builds.</p>
<p>Please look at the following link for a more detailed explanation: <a href="https://gatk.broadinstitute.org/hc/en-us/articles/360035890951-Human-genome-reference-builds-GRCh38-or-hg38-b37-hg19" rel="nofollow noreferrer">https://gatk.broadinstitute.org/hc/en-us/articles/360035890951-Human-genome-reference-builds-GRCh38-or-hg38-b37-hg19</a></p>

CC BY-SA 4.0
2021-11-23T16:27:39.170Z
2021-11-23T16:27:39.170Z
h3ab74
<p>I am looking at genomic data (HG19). I have many SNPs, their chromosomes and positions.
I want to look at certain SNP (suppose its chromosome is 1 and position 77,226,919), and extract all SNPs in distance 1mb from that SNP.</p>
<p>Are the HG19 position in terms of base-pairs? Meaning that I need to take all SNPs in position <span class="math-container">$77,226,919 \pm100,000$</span>? Or is it something else?</p>

CC BY-SA 4.0
2021-11-24T13:47:01.680Z
A megabase is 1_000_000; not 100_000.
Wouter De Coster
<snp><gwas><hg19>
HG19 Position meaning
# HG19 Position meaning

(Asked by: username_0 on 2021-11-23)

I am looking at genomic data (HG19). I have many SNPs, their chromosomes and positions.
I want to look at certain SNP (suppose its chromosome is 1 and position 77,226,919), and extract all SNPs in distance 1mb from that SNP.

Are the HG19 position in terms of base-pairs? Meaning that I need to take all SNPs in position $77,226,919 \pm100,000$? Or is it something else?

**Tags:** snp, gwas, hg19
> **Comments:**
> **username_1**: A megabase is 1_000_000; not 100_000.  

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## 2 answers

### Answer by username_2 on 2021-11-23. Score: 2

Yes, they are base pair positions


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### Answer by username_3 on 2021-11-23. Score: 1

HG19 refers to the *build* used as the reference genome. To extend on what @Emily\_Ensembl said, base pair positions may change between different builds.

Please look at the following link for a more detailed explanation: <https://gatk.broadinstitute.org/hc/en-us/articles/360035890951-Human-genome-reference-builds-GRCh38-or-hg38-b37-hg19>


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