My work seeks to break new ground in personalized treatment of sleep apnea.
recognizing these causes clinically, and to find out what factors predict individual patient responses to treatments.
American Heart Association, PI: Scott Sands, Title: Sleep apnea phenotyping for personalized therapy using clinical polysomnography.
Edwards BA, Sands SA, Skuza EM, Stockx EM, Brodecky V, Wilkinson MH, Berger PJ. Increased peripheral chemosensitivity via dopaminergic manipulation promotes respiratory instability in lambs. Respiration Physiology & Neurobiology, 2008; 164: 419-428.
Sands SA, Edwards BA, Kelly VJ, Skuza EM, Davidson MR, Wilkinson MH, Berger PJ. Mechanism underlying accelerated arterial oxygen desaturation during recurrent apnea. American Journal of Respiratory and Critical Care Medicine, 2010; 182: 961-969.
Vlahandonis A, Yiallourou SR, Sands SA, Nixon GM, Walter LM, Horne RSC. Response to ''The unnormalized spectral indices of heart rate variability should be presented in conjunction with normalized versions of the same variables.'' Sleep Medicine. 2014; 15: 843-4.
Owens RL, Eckert DJ, Jordan AS, Edwards BA, Sands SA, Malhotra A, White DP, Wellman A. An integrative model of physiological traits can be used to predict obstructive sleep apnea and response to non positive airway pressure therapy. SLEEP. 2015; 38:961-70.
Marques M, Genta PR, Sands SA, Azarbarzin A, de Melo CM, Taranto-Montemurro L, White DP, Wellman A. Effect of sleeping position on upper airway patency in obstructive sleep apnea is determined by the pharyngeal structure causing collapse. SLEEP. 2017 (Mar); 1: 40(3): zsx005.
Genta PR, Sands SA, Butler JP, Loring SH, Katz ES, Demko BG, Kezirian EJ, White DP, Wellman A. Airflow shape is associated with the pharyngeal structure causing obstructive sleep apnea. Chest. In Press.
Joosten SA. Landry SA, Sands SA, Terrill PI, Mann D, Andara C, Skuza EM, Turton A, Berger, PJ, Hamilton GS, Edwards BA. Dynamic loop gain increases upon adopting the supine body position during sleep in patients with obstructive sleep apnoea. Respirology. In Press.