Case Western Reserve University was founded in 1826 in Hudson, Ohio.
The college, which was the first in northern Ohio, took its name from the surrounding region (known at that time as the Western Reserve of Connecticut).
As a result of the prosperity of the late 19th century, the city of Cleveland, Ohio, was on the rise and it needed a university.
With funding from American industrialist Amasa Stone, the college moved in 1882 to "uptown" Cleveland.
Case Institute of Technology, a school of science and engineering, and Western Reserve University, known for its strong liberal arts and professional programmes, came together in 1967 to form Case Western Reserve University.
In U.S. News & World Report's 2013 rankings, Case Western Reserve's undergraduate programme ranked 37th among national universities.