Clare E Yellowley-Genetos, PhD; BSc (Hons)
UC Davis, School of Veterinary Medicine
Emailcyellowley@ucdavis.edu
Adenosine inhibition of lipopolysaccharide-induced interleukin-6 secretion by the osteoblastic cell line MG-63
Russell, J. M., Stephenson, G. S., Yellowley-genetos, C. E. & Benton, H. P., Oct 2007, In : Calcified Tissue International. 81, 4, p. 316-326 11 p.
Adenosine-5'-(N-ethylcarboxamide)
Age Dependence of Systemic Bone Loss and Recovery Following Femur Fracture in Mice
Emami, A. J., Toupadakis, C. A., Telek, S. M., Fyhrie, D. P., Yellowley-genetos, C. E. & Christiansen, B. A., Jan 1 2018, (Accepted/In press) In : Journal of Bone and Mineral Research.
Femoral Fractures
Osteoclasts
Analysis of a collagen II degradation protein C2C and a collagen II formation protein CP II in serumof Asian elephants (Elephas maximus)
Kilgallon, C. P., Larsen, R. S., Wong, A. & Yellowley-genetos, C. E., Mar 1 2015, In : Journal of Zoo and Wildlife Medicine. 46, 1, p. 146-149 4 p.
Elephas maximus
Elephantidae
protein degradation
Analysis of time-varying biological data using rainflow cycle counting
Jacobs, C. R., Yellowley-genetos, C. E., Nelson, D. V. & Donahue, H. J., 2000, In : Computer Methods in Biomechanics and Biomedical Engineering. 3, 1, p. 31-40 10 p.
Random errors
Fast Fourier transforms
Shear stress
Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells
Haut Donahue, T. L., Genetos, D. C., Jacobs, C. R., Donahue, H. J. & Yellowley-genetos, C. E., Sep 2004, In : Bone. 35, 3, p. 656-663 8 p.
Annexin A5
Circulating progenitor cells and the expression of Cxcl12, Cxcr4 and angiopoietinlike 4 during wound healing in the murine ear
Yellowley-Genetos, C. E., Toupadakis, C. A., Vapniarsky Arzi, N. & Wong, A., Jan 1 2019, In : PloS one. 14, 9, e0222462.
tissue repair
Comparison of the osteogenic potential of equine mesenchymal stem cells from bone marrow, adipose tissue, umbilical cord blood, and umbilical cord tissue
Toupadakis, C. A., Wong, A., Genetos, D. C., Cheung, W. K., Borjesson, D. L., Ferraro, G. L., Galuppo, L. D., Leach, J. K., Owens, S. D. & Yellowley-genetos, C. E., Oct 2010, In : American Journal of Veterinary Research. 71, 10, p. 1237-1245 9 p.
Mesenchymal Stromal Cells
Fetal Blood
Connexin expression by alveolar epithelial cells is regulated by extracellular matrix
Guo, Y., Martinez-Williams, C., Yellowley-genetos, C. E., Donahue, H. J. & Rannels, D. E., Feb 2001, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 280, 2 24-2
Alveolar Epithelial Cells
Connexin 43
Connexins
Extracellular Matrix
Gap Junctions
Cycle number and waveform of fluid flow affect bovine articular chondrocytes
Edlich, M., Yellowley-genetos, C. E., Jacobs, C. R. & Donahue, H. J., 2004, In : Biorheology. 41, 3-4, p. 315-322 8 p.
Chondrocytes
Fura-2
Detection of bacterial DNA by PCR in dogs with stifle pathology
Bhandal, J., Hayashi, K., Kim, S. Y., Klein, M., Wong, A., Toupadakis, C. A., Muir, P. & Yellowley-genetos, C. E., Oct 2013, In : Veterinary Surgery. 42, 7, p. 814-818 5 p.
Bacterial DNA
cranial cruciate ligament
Anterior Cruciate Ligament
Differential effect of steady versus oscillating flow on bone cells
Jacobs, C. R., Yellowley-genetos, C. E., Davis, B. R., Zhou, Z., Cimbala, J. M. & Donahue, H. J., Nov 1998, In : Journal of Biomechanics. 31, 11, p. 969-976 8 p.
Oscillating flow
Pulsatile flow
Differentiation of human fetal osteoblastic cells and gap junctional intercellular communication
Donahue, H. J., Li, Z., Zhou, Z. & Yellowley-genetos, C. E., 2000, In : American Journal of Physiology - Cell Physiology. 278, 2 47-2
DNA microarray analysis reveals a role for lysophosphatidic acid in the regulation of anti-inflammatory genes in MC3T3-E1 cells
Waters, K. M., Tan, R., Genetos, D. C., Verma, S., Yellowley-genetos, C. E. & Karin, N. J., Nov 2007, In : Bone. 41, 5, p. 833-841 9 p.
Effect of hypoxia on generation of neurospheres from adipose tissue-derived canine mesenchymal stromal cells
Chung, D. J., Wong, A., Hayashi, K. & Yellowley-genetos, C. E., Jan 2014, In : Veterinary Journal. 199, 1, p. 123-130 8 p.
stromal cells
Erythropoietin Receptors
Effects of cell swelling on intracellular calcium and membrane currents in bovine articular chondrocytes
Yellowley-genetos, C. E., Hancox, J. C. & Donahue, H. J., 2002, In : Journal of Cellular Biochemistry. 86, 2, p. 290-301 12 p.
Intracellular Membranes
Effects of fluid flow on intracellular calcium in bovine articular chondrocytes
Yellowley-genetos, C. E., Jacobs, C. R., Li, Z., Zhou, Z. & Donahue, H. J., Jul 1997, In : American Journal of Physiology - Cell Physiology. 273, 1 42-1
Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells
Batra, N. N., Li, Y. J., Yellowley-genetos, C. E., You, L., Malone, A. M., Chi, H. K. & Jacobs, C. R., Sep 2005, In : Journal of Biomechanics. 38, 9, p. 1909-1917 9 p.
Expression of angiopoietin-like protein 4 at the fracture site: Regulation by hypoxia and osteoblastic differentiation
Wilson, S. S., Wong, A., Toupadakis, C. A. & Yellowley-genetos, C. E., Sep 1 2015, In : Journal of Orthopaedic Research. 33, 9, p. 1364-1373 10 p.
Angiopoietins
Bony Callus
Osteogenesis
Expression of functional gap junctions in cultured pulmonary alveolar epithelial cells
Lee, Y. C., Yellowley-genetos, C. E., Li, Z., Donahue, H. J. & Rannels, D. E., Jun 1997, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 272, 6 16-6
Octanols
Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not
Reilly, G. C., Haut, T. R., Yellowley-genetos, C. E., Donahue, H. J. & Jacobs, C. R., 2003, In : Biorheology. 40, 6, p. 591-603 13 p.
Glycocalyx
Dinoprostone
Hyaluronoglucosaminidase
Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium
Saunders, M. M., You, J., Zhou, Z., Li, Z., Yellowley-genetos, C. E., Kunze, E. L., Jacobs, C. R. & Donahue, H. J., Apr 1 2003, In : Bone. 32, 4, p. 350-356 7 p.
Frequency dependent effects of oscillating fluid flow on bone cells
You, J., Saunders, M., Yellowley-genetos, C. E., Donahue, H. & Jacobs, C., 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1
Functional gap junctions between osteocytic and osteoblastic cells
Yellowley-genetos, C. E., Li, Z., Zhou, Z., Jacobs, C. R. & Donahue, H. J., 2000, In : Journal of Bone and Mineral Research. 15, 2, p. 209-217 9 p.
Gap junctional intercellular communication in bone
Donahue, H. J., Molen, M. A. V., Yellowley-genetos, C. E., Li, Z., Duncan, R. L. & Bidwell, J., 1996, In : Cells and Materials. 6, 1-3, p. 1-10 10 p.
HIF-1α regulates hypoxia-induced EP1 expression in osteoblastic cells
Genetos, D. C., Lee, C. M., Wong, A. & Yellowley-genetos, C. E., May 15 2009, In : Journal of Cellular Biochemistry. 107, 2, p. 233-239 7 p.
Hypoxia-Inducible Factor 1
Small Interfering RNA
Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts
Genetos, D. C., Toupadakis, C. A., Raheja, L. F., Wong, A., Papanicolaou, S. E., Fyhrie, D. P., Loots, G. G. & Yellowley-genetos, C. E., May 15 2010, In : Journal of Cellular Biochemistry. 110, 2, p. 457-467 11 p.
Catenins
Hypoxia increases Annexin A2 expression in osteoblastic cells via VEGF and ERK
Genetos, D. C., Wong, A., Watari, S. & Yellowley-genetos, C. E., Dec 2010, In : Bone. 47, 6, p. 1013-1019 7 p.
Neuropilin-2
Hypoxia regulates PGE2 release and EP1 receptor expression in osteoblastic cells
Lee, C. M., Genetos, D. C., You, Z. & Yellowley-genetos, C. E., Jul 2007, In : Journal of Cellular Physiology. 212, 1, p. 182-188 7 p.
Response Elements
Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway
Raheja, L. F., Genetos, D. C. & Yellowley-genetos, C. E., Feb 22 2008, In : Biochemical and Biophysical Research Communications. 366, 4, p. 1061-1066 6 p.
Conditioned Culture Medium
Hypoxic regulation of mesenchymal stem cell migration: The role of RhoA and HIF-1α
Raheja, L. F., Genetos, D. C., Wong, A. & Yellowley-genetos, C. E., Oct 1 2011, In : Cell Biology International. 35, 10, p. 981-989 9 p.
GTP Phosphohydrolases
Impaired osteoblast differentiation in annexin A2- And -A5-deficient cells
Genetos, D. C., Wong, A., Weber, T. J., Karin, N. J. & Yellowley-genetos, C. E., Sep 15 2014, In : PLoS One. 9, 9, e107482.
Annexins
Increases in Cytosolic Calcium, but not Fluid Flow, Affect Aggrecan mRNA Levels in Articular Chondrocytes
Alford, A. I., Yellowley-genetos, C. E., Jacobs, C. R. & Donahue, H. J., Dec 1 2003, In : Journal of Cellular Biochemistry. 90, 5, p. 938-944 7 p.
Aggrecans
Ionomycin
Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells
Li, Z., Zhou, Z., Yellowley-genetos, C. E. & Donahue, H. J., Dec 1999, In : Bone. 25, 6, p. 661-666 6 p.
Differentiation Antigens
Intracellular calcium changes in rat aortic smooth muscle cells in response to fluid flow
Sharma, R., Yellowley-genetos, C. E., Civelek, M., Ainslie, K., Hodgson, L., Tarbell, J. M. & Donahue, H. J., 2002, In : Annals of Biomedical Engineering. 30, 3, p. 371-378 8 p.
Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair
Toupadakis, C. A., Wong, A., Genetos, D. C., Chung, D. J., Murugesh, D., Anderson, M. J., Loots, G. G., Christiansen, B. A., Kapatkin, A. & Yellowley-genetos, C. E., Nov 2012, In : Journal of Orthopaedic Research. 30, 11, p. 1853-1859 7 p.
Fracture Healing
Hyaline Cartilage
Mechanisms contributing to fluid-flow-induced Ca2+ mobilization in articular chondrocytes
Yellowley-genetos, C. E., Jacobs, C. R. & Donahue, H. J., 1999, In : Journal of Cellular Physiology. 180, 3, p. 402-408 7 p.
Mechanosensitivity of bone cells to oscillating fluid flow induced shear stress may be modulated by chemotransport
Donahue, T. L. H., Haut, T. R., Yellowley-genetos, C. E., Donahue, H. J. & Jacobs, C. R., Sep 1 2003, In : Journal of Biomechanics. 36, 9, p. 1363-1371 9 p.
Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model
Toupadakis, C. A., Granick, J. L., Sagy, M., Wong, A., Ghassemi, E., Chung, D. J., Borjesson, D. L. & Yellowley-genetos, C. E., Sep 2013, In : Cytotherapy. 15, 9, p. 1136-1147 12 p.
Hematopoietic Stem Cell Mobilization
Nestin expression in mesenchymal stromal cells: Regulation by hypoxia and osteogenesis
Wong, A., Ghassemi, E. & Yellowley-genetos, C. E., Aug 5 2014, In : BMC Veterinary Research. 10, 1, 173.
Cell Hypoxia
bone formation
Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes
Genetos, D. C., Kephart, C. J., Zhang, Y., Yellowley-genetos, C. E. & Donahue, H. J., Jul 2007, In : Journal of Cellular Physiology. 212, 1, p. 207-214 8 p.
Oscillating fluid flow regulates cytosolic calcium concentration in bovine articular chondrocytes
Edlich, M., Yellowley-genetos, C. E., Jacobs, C. R. & Donahue, H. J., Jan 2001, In : Journal of Biomechanics. 34, 1, p. 59-65 7 p.
Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation
Li, Y. J., Batra, N. N., You, L., Meier, S. C., Coe, I. A., Yellowley-genetos, C. E. & Jacobs, C. R., Nov 2004, In : Journal of Orthopaedic Research. 22, 6, p. 1283-1289 7 p.
Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling
Kim, C. H., You, L., Yellowley-genetos, C. E. & Jacobs, C. R., Nov 2006, In : Bone. 39, 5, p. 1043-1047 5 p.
RANK Ligand
Osteogenic proliferation and differentiation of canine bone marrow and adipose tissue derived mesenchymal stromal cells and the influence of hypoxia
Chung, D. J., Hayashi, K., Toupadakis, C. A., Wong, A. & Yellowley-genetos, C. E., Feb 2012, In : Research in Veterinary Science. 92, 1, p. 66-75 10 p.
Osteopontin Gene Regulation by Oscillatory Fluid Flow via Intracellular Calcium Mobilization and Activation of Mitogen-activated Protein Kinase in MC3T3-E1 Osteoblasts
You, J., Reilly, G. C., Zhen, X., Yellowley-genetos, C. E., Chen, Q., Donahue, H. J. & Jacobs, C. R., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 13365-13371 7 p.
Mitogen-Activated Protein Kinases
Oxygen tension differentially influences osteogenic differentiation of human adipose stem cells in 2D and 3D cultures
He, J., Genetos, D. C., Yellowley-genetos, C. E. & Leach, J. K., May 1 2010, In : Journal of Cellular Biochemistry. 110, 1, p. 87-96 10 p.
Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells
Wong, A., Loots, G. G., Yellowley-genetos, C. E., Dosé, A. C. & Genetos, D. C., Dec 1 2015, In : Bone. 81, p. 97-103 7 p.
Luciferases
Prostaglandin E2 (PGE2) response to fluid flow is independent of intracellular calcium concentration in osteoblastic ROS 17/2.8 and RC×16 cells
Saunders, M., You, J., Yellowley-genetos, C. E., Donahue, H. & Jacobs, C., 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1
Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression
Genetos, D. C., Yellowley-genetos, C. E. & Loots, G. G., 2011, In : PLoS One. 6, 3, e17772.
Wnt Signaling Pathway
Prostaglandin expression profile in hypoxic osteoblastic cells
Lee, C. M., Genetos, D. C., Wong, A. & Yellowley-genetos, C. E., Jan 2010, In : Journal of Bone and Mineral Metabolism. 28, 1, p. 8-16 9 p.
Contact Clare E Yellowley-Genetos, PhD; BSc (Hons)