Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass
Bethany C. Sacks, Samer Mattar, Faisal G. Qureshi, George M. Eid, Joy L. Collins, Emma J. Barinas-Mitchell, Philip R. Schauer, Ramesh C. Ramanathan
Objectives: A precipitating factor for marginal ulcer formation after Roux-en-Y gastric bypass may be the prolonged irritation by foreign material, such as nonabsorbable suture at the gastrojejunostomy. This study examines the incidence of marginal ulcers before and after a change was made from using nonabsorbable suture to using absorbable suture for the inner layer of the anastomosis. Methods: A total of 3285 laparoscopic Roux-en-Y gastric bypass operations were performed during a 5-year period. The gastrojejunostomy technique was modified in August 2002. Those patients who developed a marginal ulcer postoperatively were identified, and their charts were retrospectively analyzed for the operative technique, patient age, history of previous gastric surgery, presence of preoperative diabetes, coronary artery disease, or peptic ulcer disease, and use of nonsteroidal anti-inflammatory medications or tobacco. Results: The incidence of marginal ulceration after Roux-en-Y gastric bypass decreased significantly from 2.6% (28/1095) with the use of nonabsorbable suture to 1.3% (29/2190) after the change to absorbable suture for the inner layer of the gastrojejunal anastomosis (P <.001). The incidence of visible suture adjacent to the ulcer on endoscopy was also significantly reduced (64.3% vs 3.4%; P <.001). When the results were corrected for length of follow-up, the difference in the incidence of ulcers occurring within 1 year of surgery remained significant between the two groups (P = .002). There were no other significant differences in the factors analyzed. Conclusions: The use of nonabsorbable sutures for the inner layer of the gastrojejunal anastomosis is associated with an increased incidence of marginal ulcers, and the adoption of absorbable suture material has reduced this incidence.
Surgery for Obesity and Related Diseases
https://doi.org/10.1016/j.soard.2005.10.013
Precipitating Factors
Anastomosis
Laparoscopic gastric bypass
Marginal ulcer
Morbid obesity
Roux-en-Y
Sacks, B. C., Mattar, S., Qureshi, F. G., Eid, G. M., Collins, J. L., Barinas-Mitchell, E. J., ... Ramanathan, R. C. (2006). Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass. Surgery for Obesity and Related Diseases, 2(1), 11-16. https://doi.org/10.1016/j.soard.2005.10.013
Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass. / Sacks, Bethany C.; Mattar, Samer; Qureshi, Faisal G.; Eid, George M.; Collins, Joy L.; Barinas-Mitchell, Emma J.; Schauer, Philip R.; Ramanathan, Ramesh C.
In: Surgery for Obesity and Related Diseases, Vol. 2, No. 1, 01.2006, p. 11-16.
Sacks, BC, Mattar, S, Qureshi, FG, Eid, GM, Collins, JL, Barinas-Mitchell, EJ, Schauer, PR & Ramanathan, RC 2006, 'Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass', Surgery for Obesity and Related Diseases, vol. 2, no. 1, pp. 11-16. https://doi.org/10.1016/j.soard.2005.10.013
Sacks BC, Mattar S, Qureshi FG, Eid GM, Collins JL, Barinas-Mitchell EJ et al. Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass. Surgery for Obesity and Related Diseases. 2006 Jan;2(1):11-16. https://doi.org/10.1016/j.soard.2005.10.013
Sacks, Bethany C. ; Mattar, Samer ; Qureshi, Faisal G. ; Eid, George M. ; Collins, Joy L. ; Barinas-Mitchell, Emma J. ; Schauer, Philip R. ; Ramanathan, Ramesh C. / Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass. In: Surgery for Obesity and Related Diseases. 2006 ; Vol. 2, No. 1. pp. 11-16.
@article{9b04f6e4d6da4aeb87b2ef3d8f977099,
title = "Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass",
abstract = "Objectives: A precipitating factor for marginal ulcer formation after Roux-en-Y gastric bypass may be the prolonged irritation by foreign material, such as nonabsorbable suture at the gastrojejunostomy. This study examines the incidence of marginal ulcers before and after a change was made from using nonabsorbable suture to using absorbable suture for the inner layer of the anastomosis. Methods: A total of 3285 laparoscopic Roux-en-Y gastric bypass operations were performed during a 5-year period. The gastrojejunostomy technique was modified in August 2002. Those patients who developed a marginal ulcer postoperatively were identified, and their charts were retrospectively analyzed for the operative technique, patient age, history of previous gastric surgery, presence of preoperative diabetes, coronary artery disease, or peptic ulcer disease, and use of nonsteroidal anti-inflammatory medications or tobacco. Results: The incidence of marginal ulceration after Roux-en-Y gastric bypass decreased significantly from 2.6{\%} (28/1095) with the use of nonabsorbable suture to 1.3{\%} (29/2190) after the change to absorbable suture for the inner layer of the gastrojejunal anastomosis (P <.001). The incidence of visible suture adjacent to the ulcer on endoscopy was also significantly reduced (64.3{\%} vs 3.4{\%}; P <.001). When the results were corrected for length of follow-up, the difference in the incidence of ulcers occurring within 1 year of surgery remained significant between the two groups (P = .002). There were no other significant differences in the factors analyzed. Conclusions: The use of nonabsorbable sutures for the inner layer of the gastrojejunal anastomosis is associated with an increased incidence of marginal ulcers, and the adoption of absorbable suture material has reduced this incidence.",
keywords = "Anastomosis, Bariatric surgery, Laparoscopic gastric bypass, Marginal ulcer, Morbid obesity, Postoperative complications, Roux-en-Y",
author = "Sacks, {Bethany C.} and Samer Mattar and Qureshi, {Faisal G.} and Eid, {George M.} and Collins, {Joy L.} and Barinas-Mitchell, {Emma J.} and Schauer, {Philip R.} and Ramanathan, {Ramesh C.}",
doi = "10.1016/j.soard.2005.10.013",
journal = "Surgery for Obesity and Related Diseases",
T1 - Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass
AU - Sacks, Bethany C.
AU - Mattar, Samer
AU - Qureshi, Faisal G.
AU - Eid, George M.
AU - Collins, Joy L.
AU - Barinas-Mitchell, Emma J.
AU - Schauer, Philip R.
AU - Ramanathan, Ramesh C.
N2 - Objectives: A precipitating factor for marginal ulcer formation after Roux-en-Y gastric bypass may be the prolonged irritation by foreign material, such as nonabsorbable suture at the gastrojejunostomy. This study examines the incidence of marginal ulcers before and after a change was made from using nonabsorbable suture to using absorbable suture for the inner layer of the anastomosis. Methods: A total of 3285 laparoscopic Roux-en-Y gastric bypass operations were performed during a 5-year period. The gastrojejunostomy technique was modified in August 2002. Those patients who developed a marginal ulcer postoperatively were identified, and their charts were retrospectively analyzed for the operative technique, patient age, history of previous gastric surgery, presence of preoperative diabetes, coronary artery disease, or peptic ulcer disease, and use of nonsteroidal anti-inflammatory medications or tobacco. Results: The incidence of marginal ulceration after Roux-en-Y gastric bypass decreased significantly from 2.6% (28/1095) with the use of nonabsorbable suture to 1.3% (29/2190) after the change to absorbable suture for the inner layer of the gastrojejunal anastomosis (P <.001). The incidence of visible suture adjacent to the ulcer on endoscopy was also significantly reduced (64.3% vs 3.4%; P <.001). When the results were corrected for length of follow-up, the difference in the incidence of ulcers occurring within 1 year of surgery remained significant between the two groups (P = .002). There were no other significant differences in the factors analyzed. Conclusions: The use of nonabsorbable sutures for the inner layer of the gastrojejunal anastomosis is associated with an increased incidence of marginal ulcers, and the adoption of absorbable suture material has reduced this incidence.
AB - Objectives: A precipitating factor for marginal ulcer formation after Roux-en-Y gastric bypass may be the prolonged irritation by foreign material, such as nonabsorbable suture at the gastrojejunostomy. This study examines the incidence of marginal ulcers before and after a change was made from using nonabsorbable suture to using absorbable suture for the inner layer of the anastomosis. Methods: A total of 3285 laparoscopic Roux-en-Y gastric bypass operations were performed during a 5-year period. The gastrojejunostomy technique was modified in August 2002. Those patients who developed a marginal ulcer postoperatively were identified, and their charts were retrospectively analyzed for the operative technique, patient age, history of previous gastric surgery, presence of preoperative diabetes, coronary artery disease, or peptic ulcer disease, and use of nonsteroidal anti-inflammatory medications or tobacco. Results: The incidence of marginal ulceration after Roux-en-Y gastric bypass decreased significantly from 2.6% (28/1095) with the use of nonabsorbable suture to 1.3% (29/2190) after the change to absorbable suture for the inner layer of the gastrojejunal anastomosis (P <.001). The incidence of visible suture adjacent to the ulcer on endoscopy was also significantly reduced (64.3% vs 3.4%; P <.001). When the results were corrected for length of follow-up, the difference in the incidence of ulcers occurring within 1 year of surgery remained significant between the two groups (P = .002). There were no other significant differences in the factors analyzed. Conclusions: The use of nonabsorbable sutures for the inner layer of the gastrojejunal anastomosis is associated with an increased incidence of marginal ulcers, and the adoption of absorbable suture material has reduced this incidence.
KW - Anastomosis
KW - Bariatric surgery
KW - Laparoscopic gastric bypass
KW - Marginal ulcer
KW - Morbid obesity
KW - Postoperative complications
KW - Roux-en-Y
U2 - 10.1016/j.soard.2005.10.013
DO - 10.1016/j.soard.2005.10.013
JO - Surgery for Obesity and Related Diseases
JF - Surgery for Obesity and Related Diseases
10.1016/j.soard.2005.10.013