APC anti-mouse CD48 Antibody
HM48-1 (See other available formats)
BCM1, SLAMF2, Blast-1
Armenian Hamster IgG
C57BL/6 mouse splenocytes stained with HM48-1 APC
103411 25 µg 68,00€
103412 100 µg 212,00€
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.
Mouse T lymphoma MBL-2
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
The HM48-1 antibody is useful for blocking in vitro and in vivo CD48 mediated interactions. Additional reported applications (for the relevant formats) include: immunoprecipitation1, costimulation of T cell proliferation1,2, blocking of CD48-CD2 interaction1, and inhibition of CTL activity and graft rejection1,2. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. Nos. 103452-103456) with a lower endotoxin limit (Endotoxin < 0.01 EU/µg).
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AB_571996 (BioLegend Cat. No. 103411)
Ig superfamily, 45 kD
T cells and B cells, monocytes/macrophages
Adhesion, T cell recognition
CD2, CD244
B cells, Macrophages, Monocytes, T cells
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