Q: no changes to deploy android studio 2.1 Android Studio 2.1 instant run is not updating the app on the device
I observed an issue with AndroidStudio 2.1. When I run the app with small java code changes, it doesn't update app on the device sometimes. Instead it shows a message 

No changes to deploy // (Don't show again)

Am I missing any thing here?
As a work around I do clean build every time in order to reflect the changes in app.

A: Upgrade Android studio version to 3 or more. this bug is resolved.
This was a bug on version 2.0 instant run and issues were reported check these links 
https://code.google.com/p/android/issues/detail?id=199884 https://code.google.com/p/android/issues/detail?id=195062
https://code.google.com/p/android/issues/detail?id=206698
https://code.google.com/p/android/issues/detail?id=209413
https://code.google.com/p/android/issues/detail?id=206627
thing to do would be to disable Instant Run entirely by 

Settings > Build, Execution, Deployment > Instant Run > Enable
  Instant Run

You can file a bug at this link: Google Issue Tracker
please check this answer https://stackoverflow.com/a/35169716/2826147 to turn it off.

A: Thats a bug in Android Studio, I noticed it in build 2.0 sometimes it failed to update, so what i do is I rebuild the entire project, one more thing, if you have multidex enabled and your device is not running 5 <it will not work, make sure its disabled and rebuild your project. 

A: I have just noticed that whenever i closed my app and then run it worked. See my post here. 
https://stackoverflow.com/a/37357665/5923606
