Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-4, Mouse Monoclonal Antibody.
c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.
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