Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus
Gabriella De Rosa, Marco Piastra, Manuela Pardeo, Elena Caresta, Arnaldo Capelli
Dipartimento di Scienze della vita e sanità pubblica
Ambito disciplinare: Clinica Pediatrica
Dipartimento di Scienze biotecnologiche di base, cliniche intensivologiche e perioperatorie
Ambito disciplinare: Clinica Anestesiologica
Congenital anomalous origins of the coronary arteries represents a rare but well-described cause of myocardial ischemia and sudden death. Left coronary artery (LCA) arising from the right sinus of Valsalva is a rare congenital coronary anomaly that seems to be commonly associated with sudden death in young trained athletes. The possibility of a coronary artery anomaly should always be considered in young individuals with a history of chest pain or syncope, particularly if the episodes are triggered by exercise. We describe a case of congenital LCA anomaly in an asymptomatic 10-year-old girl with no family history of sudden death; no previous unexplained syncopal episodes or exercise-induced symptoms were reported. She experienced a cardiac arrest while she was resting at school and was not recoverable despite early emergency department admission and intensive prolonged cardiopulmonary resuscitation attempts. Post-mortem pathological findings revealed a single origin from the right sinus of Valsalva for both right and left coronary arteries. The LCA was compressed between the aorta and the pulmonary trunk. Histologic features suggested recent ischemia. Although sudden death can be the first manifestation of this condition, it is important to be particularly aware of prodromic symptoms: exertional dyspnea, chest pain, syncope or dizziness. Recognition during life of this coronary anomaly is mandatory to prevent the risk of sudden death and to plan surgical correction if clinically indicated.
left coronary artery
right aortic sinus
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Sudden Death Medicine and Dentistry 100%
Left Coronary Artery Medicine and Dentistry 83%
Coronary Artery Anomaly Medicine and Dentistry 66%
Exercise Medicine and Dentistry 50%
Faintness Medicine and Dentistry 33%
Thorax Pain Medicine and Dentistry 33%
Symptom Medicine and Dentistry 33%
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De Rosa, G., Piastra, M., Pardeo, M., Caresta, E., & Capelli, A. (2005). Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus. Journal of Emergency Medicine, 437-441.
De Rosa, Gabriella ; Piastra, Marco ; Pardeo, Manuela et al. / Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus. In: Journal of Emergency Medicine. 2005 ; pagg. 437-441.
@article{4f65fdcf8abe4b02a7ede50b236fa1fc,
title = "Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus",
abstract = "Congenital anomalous origins of the coronary arteries represents a rare but well-described cause of myocardial ischemia and sudden death. Left coronary artery (LCA) arising from the right sinus of Valsalva is a rare congenital coronary anomaly that seems to be commonly associated with sudden death in young trained athletes. The possibility of a coronary artery anomaly should always be considered in young individuals with a history of chest pain or syncope, particularly if the episodes are triggered by exercise. We describe a case of congenital LCA anomaly in an asymptomatic 10-year-old girl with no family history of sudden death; no previous unexplained syncopal episodes or exercise-induced symptoms were reported. She experienced a cardiac arrest while she was resting at school and was not recoverable despite early emergency department admission and intensive prolonged cardiopulmonary resuscitation attempts. Post-mortem pathological findings revealed a single origin from the right sinus of Valsalva for both right and left coronary arteries. The LCA was compressed between the aorta and the pulmonary trunk. Histologic features suggested recent ischemia. Although sudden death can be the first manifestation of this condition, it is important to be particularly aware of prodromic symptoms: exertional dyspnea, chest pain, syncope or dizziness. Recognition during life of this coronary anomaly is mandatory to prevent the risk of sudden death and to plan surgical correction if clinically indicated.",
keywords = "left coronary artery, right aortic sinus, sudden death, left coronary artery, right aortic sinus, sudden death",
author = "{De Rosa}, Gabriella and Marco Piastra and Manuela Pardeo and Elena Caresta and Arnaldo Capelli",
journal = "Journal of Emergency Medicine",
publisher = "Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010",
De Rosa, G, Piastra, M, Pardeo, M, Caresta, E & Capelli, A 2005, 'Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus', Journal of Emergency Medicine, pagg. 437-441.
Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus. / De Rosa, Gabriella; Piastra, Marco; Pardeo, Manuela et al.
In: Journal of Emergency Medicine, 2005, pag. 437-441.
T1 - Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus
AU - De Rosa, Gabriella
AU - Piastra, Marco
AU - Pardeo, Manuela
AU - Caresta, Elena
AU - Capelli, Arnaldo
N2 - Congenital anomalous origins of the coronary arteries represents a rare but well-described cause of myocardial ischemia and sudden death. Left coronary artery (LCA) arising from the right sinus of Valsalva is a rare congenital coronary anomaly that seems to be commonly associated with sudden death in young trained athletes. The possibility of a coronary artery anomaly should always be considered in young individuals with a history of chest pain or syncope, particularly if the episodes are triggered by exercise. We describe a case of congenital LCA anomaly in an asymptomatic 10-year-old girl with no family history of sudden death; no previous unexplained syncopal episodes or exercise-induced symptoms were reported. She experienced a cardiac arrest while she was resting at school and was not recoverable despite early emergency department admission and intensive prolonged cardiopulmonary resuscitation attempts. Post-mortem pathological findings revealed a single origin from the right sinus of Valsalva for both right and left coronary arteries. The LCA was compressed between the aorta and the pulmonary trunk. Histologic features suggested recent ischemia. Although sudden death can be the first manifestation of this condition, it is important to be particularly aware of prodromic symptoms: exertional dyspnea, chest pain, syncope or dizziness. Recognition during life of this coronary anomaly is mandatory to prevent the risk of sudden death and to plan surgical correction if clinically indicated.
AB - Congenital anomalous origins of the coronary arteries represents a rare but well-described cause of myocardial ischemia and sudden death. Left coronary artery (LCA) arising from the right sinus of Valsalva is a rare congenital coronary anomaly that seems to be commonly associated with sudden death in young trained athletes. The possibility of a coronary artery anomaly should always be considered in young individuals with a history of chest pain or syncope, particularly if the episodes are triggered by exercise. We describe a case of congenital LCA anomaly in an asymptomatic 10-year-old girl with no family history of sudden death; no previous unexplained syncopal episodes or exercise-induced symptoms were reported. She experienced a cardiac arrest while she was resting at school and was not recoverable despite early emergency department admission and intensive prolonged cardiopulmonary resuscitation attempts. Post-mortem pathological findings revealed a single origin from the right sinus of Valsalva for both right and left coronary arteries. The LCA was compressed between the aorta and the pulmonary trunk. Histologic features suggested recent ischemia. Although sudden death can be the first manifestation of this condition, it is important to be particularly aware of prodromic symptoms: exertional dyspnea, chest pain, syncope or dizziness. Recognition during life of this coronary anomaly is mandatory to prevent the risk of sudden death and to plan surgical correction if clinically indicated.
KW - left coronary artery
KW - right aortic sinus
KW - sudden death
JO - Journal of Emergency Medicine
JF - Journal of Emergency Medicine
De Rosa G, Piastra M, Pardeo M, Caresta E, Capelli A. Exercise -unrelated sudden death as the first event of anomalous origin of the left coronary artery from the right aortic sinus. Journal of Emergency Medicine. 2005;437-441.