RANDY LINDE, M.D.; HARRISON J. SHULL, M.D.; SAM MARNEY, M.D.; PETER W. STACPOOLE, PH.D., M.D.; DAVID RABIN, M.D.
PETER W. STACPOOLE, PH.D., M.D.
To the editor: Recent reports have detailed the effectiveness of H2 receptor antagonist therapy (1, 2) in the treatment of gastric hypersecretion and diarrhea in systemic mastocytosis. We report another such case in which normal bowel habits returned after treatment with H1 and H2 blocking agents, suggesting that her diarrhea was due to excessive release of mast-cell histamine.
Published: Ann Intern Med. 1980;92(5):716.