Francisco "Isco" Alarcon, little-used defender Achraf Hakimi, and Toni Kroos added on, along with an own goal by Celta's Sergi Gomez, to ease to the big win.
Real Madrid's Gareth Bale (R) celebrates his goal with teammates.
Madrid plays Villarreal in the final round of the Liga season before the Champions League final on May 26 in Kiev.
Manager Zinedine Zidane left Ronaldo off his squad a week after a right ankle injury caused Madrid's star to be substituted last weekend against Liga champions Barcelona.
However, he also scored in the 1-0 victory in the second leg of the Europa League semi-final against Arsenal, earning Atletico a place in Wednesday's final and ending Arsene Wenger's last hopes of European glory with the Gunners.
"Costa came back here for nights like this; to be important, to lead from the front", said Simeone.
Bale struck the first goal of Real's thrashing of Celta with a surging run forward and low finish. Jorge "Koke" Resurreccion scores from a pass by Antoine Griezmann in the eighth minute.
"We cannot control things like this, all we can do is help him to feel good with us", said Atletico captain Gabi.
Team mate Saul Niguez, however, believes only one thing will be on Griezmann's mind in Lyon. "We're going to try and make the most competitive team possible against an opponent that is having a fantastic season".
Real Betis drew an exciting local derby with Sevilla 2-2 to a Europa League place and they will finish above their city rivals for the first time in five seasons, although the point assured Sevilla of seventh spot and a playoff berth for Europe's secondary competition.
Sociedad's players wore shirts that included an image of Prieto in the center of the club's badge to honor his 500-plus appearances.
Atletico released a statement last week saying they were "fed up with Barcelona's attitude" after president Josep Maria Bartomeu admitted he had spoken with Griezmann's agent and striker Luis Suarez said he welcomed the Frenchman's imminent arrival at the Nou Camp.
Other actresses including Hazel Keech, Sagarika Ghatge and Sonam Kapoor chose to wear red on their wedding day itself. Sonam Kapoor known not just for her powerful on-screen performances but also for her great taste in fashion.
The reason being, the network related infrastructure for pairing the Watch with iPhone isn't set inside India. After the revision of the Airtel prepaid plan 149, the plan now competes with the Reliance Jio Plan 149.
The four-legged robot extends its mechanical arm, turns the door handle and opens it, letting both robots through. It's unclear how much the robots will cost or who will be eligible to purchase them.
Prince Harry and Meghan Markles relationship is transatlantic, and now their wedding ceremony will be too. Welby said on Twitter that he was thrilled the couple selected Curry to give the address.
Former Borussia Monchengladbach coach Lucien Favre is tipped to leave French side Nice to replace him. Peter Stoger was a surprising choice by Dortmund but only time will tell if it was the right one.