Age and cell type-specific transcript profiles in the mouse prostate. A) Principal component analysis (PCA) for microdisected dorsal prostate stroma and epithelium from young and old animals. PCA discriminates epithelial and stromal samples. EO: old epithelium; EY: young epithelium; SO: old stroma; SY: young stroma. B) Transcript abundance
Age and cell type-specific transcript profiles in the mouse prostate. A ) Principal Component Analysis (PCA) for microdissected dorsal prostate stroma and epithelium from young and old animals. PCA discriminates epithelial and stromal samples. EO : old epithelium; EY : young epithelium; SO : old stroma; SY : young stroma. B ) Transcript abundance levels (Log2 Ratios) obtained from microarray-based measurements for genes known to exhibit preferentially expression in stromal or epithelial cells. Red indicates increased expression; green indicates decreased expression. C ) Heat map of age-associated transcripts in the prostate stroma (p 